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Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might be advisable to allocate patients randomly in the other ratios when comparing a new treatment with the old one, or when one treatment is quite difficult or expensive to administer. The chance of detecting the real difference between the two treatments is not reduced much as long as the m ratio is not more extreme than 2:1.
Computer-assisted interviews : A method or technique of interviewing subjects in which the interviewer reads the question from the computer screen instead of the printed page, and
Collapsing categories : A procedure generally applied to contingency tables in which the two or more row or column categories are combined, in number of cases so as to yield the re
Relative risk is the measure of the association between the exposure to a particular factor and the risk or probability of a convinced outcome, calculated as follows therefor
Case series : It is the series of reports on the condition of the individual patients made by treating physician. Such reports might be helpful and informative for the rare disease
Coincidences : Astonishing concurrence of the events, perceived as meaningfully related, with no apparent causal connection. Such type of events abounds in everyday life and is oft
Multi-hit model is the model for a toxic response which results from the random occurrence of one or the more fundamental biological events. A response is supposed to be induced o
Conditional logistic regression : The form of logistic regression designed to work with the clustered data, such as data including matched pairs of the subjects, in which subject-s
Matching coefficient is a similarity coefficient for data consisting of the number of binary variables which is often used in cluster analysis. It can be given as follows he
Behrens Fisher problem : The difficulty of testing for the equality of the means of the two normal distributions which do not have the equal variance. Various test statistics have
Last observation carried forward is a technique for replacing the observations of the patients who drop out of the clinical trial carried out over a time period. It consists of su
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