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Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might be advisable to allocate patients randomly in the other ratios when comparing a new treatment with the old one, or when one treatment is quite difficult or expensive to administer. The chance of detecting the real difference between the two treatments is not reduced much as long as the m ratio is not more extreme than 2:1.
Historical controls : The group of patients treated in the past with the standard therapy, taken in use as the control group for evaluating the new treatment on the present patient
Latent class analysis is a technique of assessing whether the set of observations including q categorical variables, in specific, binary variables, consists of the number of diffe
The graphical method for studying the behavior of the seasonal time series. In such a plot, the January values of seasonal component are graphed for the upcoming years, then the
Quality-adjusted survival analysis is a method for evaluating the effects of treatment on survival which allows the consideration of quality of life as well as the quantity of lif
Interim analyses : An analysis made before the planned end of a clinical trial, typically with the aim of detecting the treatment differences at the early stage and thus preventing
The Current status data arise in the survival analysis if the observations are limited to the indicators of whether or not the event of interest has happened at the time the sample
Non linear mapping (NLM ) is a technique for obtaining a low-dimensional representation of the set of multivariate data, which operates by minimizing a function of the differences
Maximum likelihood estimation is an estimation procedure involving maximization of the likelihood or the log-likelihood with respect to the parameters. Such type of estimators is
Chernoff's faces : A method or technique for representing the multivariate data graphically. Each observation is represented by the computer-created face, the features of which are
Categorizing continuous variables : A practice which involves the conversion of the continuous variables into the series of the categories, which is common in the field of medical
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