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Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might be advisable to allocate patients randomly in the other ratios when comparing a new treatment with the old one, or when one treatment is quite difficult or expensive to administer. The chance of detecting the real difference between the two treatments is not reduced much as long as the m ratio is not more extreme than 2:1.
Chi-squared distribution : It is the probability distribution, f (x), of the random variable de?ned as the sum of squares of the number (v) of independent standard normal variables
The probability distribution, f (x), of largest extreme can be given as The location parameter, α is the mode and β is the scale parameter. The mean, variance skewn
Bimodal distribution : The probability distribution, or we can simply say the frequency distribution, with two modes. Figure 15 shows the example of each of them
Clinical trials : Medical experiments designed to assess which of two or more treatments is much more effective. It is based on one of the oldest philosophy of the scienti?c resear
Inliers is the term used for the observations most likely to be subject to error in situations where the dichotomy is developed by making a ‘cut’ on an ordered scale, and where th
Mauchly test is a test which a variance-covariance matrix of pair wise differences of responses in the set of longitudinal data is the scalar multiple of identity matrix, a proper
Comparative exposure rate : A measure of alliance for use in a matched case-control study, de?ned as the ratio of the number of case-control pairs, where the case has greater expos
Matching is the method of making a study group and a comparison group comparable with respect to the extraneous factors. Generally used in the retrospective studies when selecting
Quality control procedures is the statistical process designed to ensure that the precision and accuracy of, for instance, a laboratory test, are maintained within the acceptable
Kendall's tau statistics : The measures of the correlation between the two sets of rankings. Kendall's tau itself (τ) is the rank correlation coefficient based on number of inversi
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