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Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might be advisable to allocate patients randomly in the other ratios when comparing a new treatment with the old one, or when one treatment is quite difficult or expensive to administer. The chance of detecting the real difference between the two treatments is not reduced much as long as the m ratio is not more extreme than 2:1.
This is extension of the EM algorithm which typically converges more slowly than EM in terms of the iterations but can be much faster in the whole computer time. The general idea o
Genetic algorithms: The optimization events motivated by the biological analogies. The prime idea is to try to mimic the 'survival of the fittest' rule of the genetic mutation in
The procedure for clustering variables in the multivariate data, which forms the clusters by performing one or other of the below written three operations: * combining two varia
i have an assignment for experimental design which is must done by SAS program can you help me also i need to hand in the assignment till thursday shall i send it for you ?
It is the art of attempting to exchange something quite small and certain, for something which are large and uncertain. Gambling is big business; in the US, for instance, it is at
Matching distribution is a probability distribution which arises in the following manner. Suppose that the set of n subjects, numbered 1; . . . ; n respectively, are arranged in
Models which make use of the smoothing techniques such as locally weighted regression to identify and represent the possible non-linear relationships between the explanatory and th
Confidence interval : A range of the values, calculated from the sample observations which is believed, with the particular probability, to posses the true parameter value. A 95% c
Clinical vs. statistical significance : The distinction among results in terms of their possible clinical importance rather than simply in terms of their statistical importance. Wi
It is an informal method of assessing the effect of the publication bias, generally in the context of the meta-analysis. The effect measures from each of the reported study are plo
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