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Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might be advisable to allocate patients randomly in the other ratios when comparing a new treatment with the old one, or when one treatment is quite difficult or expensive to administer. The chance of detecting the real difference between the two treatments is not reduced much as long as the m ratio is not more extreme than 2:1.
Isobologram is a diagram used to characterize the interactions among jointly administered drugs or the chemicals. The contour of the constant response (that is the isobole), which
Suppose we estimate the following model: Passengersi = 1 + 2Populationi + ui a) Generate a scatter plot with passengers on the vertical axis and population on the horizonta
This is the powerful visualization tool for studying how the response relies on an explanatory variable given the values of other explanatory variables. The plot comprises of a num
This term sometimes is applied to the model for explaining the differences found between naturally happening groups which are greater than those observed on some previous occasion;
Median is the value in a set of the ranked observations which divides the data into two parts of equal size. When there are an odd number of observations the median is middle v
Consolidated Standards for Reporting Trials (CONSORT) statement : The protocol for reporting the results of the clinical trials. The core contribution of the statement comprises of
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The Null Hypothesis - H0: β0 = 0, H0: β 1 = 0, H0: β 2 = 0, Β i = 0 The Alternative Hypothesis - H1: β0 ≠ 0, H0: β 1 ≠ 0, H0: β 2 ≠ 0, Β i ≠ 0 i =0, 1, 2, 3
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Goodmanand kruskal measures of association is the measures of associations which are useful in the situation where two categorical variables cannot be supposed to be derived from
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