Transcription factors have multiple domains, Biology

Assignment Help:

In most cases, the transcription factors in eukaryotes which bind to promoter   or enhancer sequences   are activator   proteins   which induce   transcription.   That proteins generally have at least two distinct domains of protein structure, a DNA- binding  domain  which identify  the specific DNA sequence  to bind to and an activation  domain responsible  for bringing  about the transcriptional  activation by  interaction  with  other  transcription   factors  and the  RNA  polymerase molecule. Various transcription factors operate as dimers, either homodimers (identical subunits) or heterodimers (dissimilar subunits) with the subunits held together through dimerization domains. The DNA dimerization domains and binding domains have characteristic protein structures (motifs) which are explained2440_22.png

Figure: Looping out of DNA permitting the interaction of enhancer-bound factor(s) with the transcription initiation complex.

below. At last, some transcription factors example for steroid hormone receptors are responsive  to specific  short  molecules  (ligands)  that  regulate  the activity  of the  transcription  factor.  In these cases, the ligand binds at a ligand-binding domain.


Related Discussions:- Transcription factors have multiple domains

Explain triangular full mucoperiosteal flaps, Explain Triangular Full Mucop...

Explain Triangular Full Mucoperiosteal Flaps - Endodontic Surgery      - Only vertical releasing incision with the Horizontal incision, -Used at the area of important anatom

Photosynthetic function, Photosynthetic function Structural organisa...

Photosynthetic function Structural organisation of the leaf is suitable to perform the process of photosynthesis. Hence leaf is called as a food factory. The leaf has a l

Describe the implant in an infected socket, Placement of the Implant in an ...

Placement of the Implant in an Infected Socket or a Pathologic Lesion Dental implants may fail due to: 1) Placement of the implant fixture into an infected socket (during im

Cloning, Cloning Cloning is the procedure of creating an identical copy...

Cloning Cloning is the procedure of creating an identical copy of something. It together refers to procedures used to form copies of DNA fragments (molecular cloning), cells (c

What is portal and rental circulation, What is Portal and Rental Circulatio...

What is Portal and Rental Circulation ? The body has other circulation systems that do not return blood directly to the heart. For instance, the blood that drains from the abdo

RESPIRATION, I HAVE TO MAKE A ASSIGNMENT ON RESPIRATION

I HAVE TO MAKE A ASSIGNMENT ON RESPIRATION

What is polysaccharides, What is Polysaccharides? Polysaccharides:  M...

What is Polysaccharides? Polysaccharides:  Many monosaccharide subunits can be joined to form long, complex polysaccharide molecules. These complex sugars are often used to s

Statements concerning the inheritance of a dominant trait, Which of the fol...

Which of the following statements concerning the inheritance of a dominant trait is true? Every affected person must have at least one affected parent. The trait is observed to ski

Advantages of stage two done with tissue punch, Advantages of Stage two don...

Advantages of Stage two done with tissue punch - Less traumatic to surrounding tissue - Faster progress to the impression procedure - No sutures required

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd