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In most cases, the transcription factors in eukaryotes which bind to promoter or enhancer sequences are activator proteins which induce transcription. That proteins generally have at least two distinct domains of protein structure, a DNA- binding domain which identify the specific DNA sequence to bind to and an activation domain responsible for bringing about the transcriptional activation by interaction with other transcription factors and the RNA polymerase molecule. Various transcription factors operate as dimers, either homodimers (identical subunits) or heterodimers (dissimilar subunits) with the subunits held together through dimerization domains. The DNA dimerization domains and binding domains have characteristic protein structures (motifs) which are explained
Figure: Looping out of DNA permitting the interaction of enhancer-bound factor(s) with the transcription initiation complex.
below. At last, some transcription factors example for steroid hormone receptors are responsive to specific short molecules (ligands) that regulate the activity of the transcription factor. In these cases, the ligand binds at a ligand-binding domain.
Define about the term Indicators? The easiest way to determine when the reaction is complete is by using indicators. An indicator is a compound that has a physical property (us
what is micelle
Steps for Prevention Industrial Accidents These steps are as follow: Substitute a less hazardous equivalent. Remove worker from hazard (e.g. automate the sys
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Which of the following is true for the sodium-glucose co-transporter? A. The net flux of sodium ions is from a region of high sodium ion concentration to a region of low sodium
The metabolism of phenylalanine will now be taken in some detail, as two inborn errors of metabolism are known which affect this pathway. The Phenylalanine is 1st hydroxylated by p
#question.characteristics of coelenterata?.
Explain Rifabutin Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor lev
VACUOLES They are of 4 types - 1. Sap Vacuole - Outer membrane of sap vacuole is called T onoplast . Sap vacuole contains amino sugars, carotenoids, proteins, m
1.How does the skin on your palm differ from that on the back (posterior) of your hand? 2.Describe the differences observed in the type and distribution of hair on the front (anter
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