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The quartenary structure of a holoenzyme contains four long polypeptide subunits composed of non-polar, polar and charged amino acids. All subunits are properly folded and functional in a water environment. Hydrogen bonds formed with the subunit polypeptides might likely be found:
I. between atoms that comprise the repetitive backbone
II between atoms that comprise the R-groups sidechains in each subunit polypeptides
III between water in the environment and the amino and carboxyl (C-terminal) ends of the polypeptides
In high altitudes is it necessary for the blood to have more or less hemoglobin? In high altitudes the air is rarefied and oxygen concentration is lower than in low altitudes.
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