Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

What is dengue, What is dengue? Dengue, or dengue fever, is an epidemic...

What is dengue? Dengue, or dengue fever, is an epidemic disease in some countries (for instance, in Brazil), and its most dangerous form is hemorrhagic dengue. It is caused by

Explain about the diabetes mellitus, Explain about the Diabetes mellitus? ...

Explain about the Diabetes mellitus? You are aware that diabetes may be diagnosed as an exaggerated response in blood glucose concentration following ingestion of a fixed amou

What is the probability the child will have pku, PKU is a recessive disorde...

PKU is a recessive disorder. Suppose two people who were heterozygous for PKU married and had a child. What is the probability that the child will have PKU?

What are muscle tissues, Q What are muscle tissues? How is the function of ...

Q What are muscle tissues? How is the function of this tissue related to the typical characteristics of its cells? Muscle tissues are that tissues which are made of cells able

How do grasslands differ from savannas, How do grasslands differ from Savan...

How do grasslands differ from Savannas? Name the two main categories of plant forms that dominate the desert vegetation.

Soil temperature, Soil Temperature Soil temperature is known to influe...

Soil Temperature Soil temperature is known to influence water absorption and ultimately transpiration to a considerable extent. In many plants water absorption is reduced shar

What is microtubules, What is Microtubules? Microtubules are the largest...

What is Microtubules? Microtubules are the largest intracellular fibers, with a diameter of about 25 nm (2.5 x 10-8 meters). They consist of hollow fibers composed of a protein

Explain what is class osteichthyes , Explain what is Class Osteichthyes ? ...

Explain what is Class Osteichthyes ? Class Osteichthyes takes its name from the Greek root "osteo," referring to bone, and "ichthys," referring to fish. The bony fish have a sk

Explain about suspensions, Explain about Suspensions Sol is a colloidal...

Explain about Suspensions Sol is a colloidal system, in which solid particles are dispersed in a liquid. When the particles of a solid are separated into large aggregates of pa

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd