Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Explain counseling strategies, Counseling Strategies The counseling str...

Counseling Strategies The counseling strategies which may serve  lo be useful are described herewith. Individual Counseling: Individual counseling is personal counseling.  T

Shock, S h o c k It is defined as a generalized acute reduction in ...

S h o c k It is defined as a generalized acute reduction in the perfusion of tissues by which there is oxygen deficiency in the cells. It is characterized by reduction in e

Explain calvin cycle, Calvin cycle (the aka Calvin-Benson Cycle or the Car...

Calvin cycle (the aka Calvin-Benson Cycle or the Carbon Fixation) is the series of biochemical, enzyme-mediated reactions during which the atmospheric carbon dioxide is reduced an

The deficiency in hepatic glucose 6 phosphatase, Under fasting conditions, ...

Under fasting conditions, individuals with a deficiency in hepatic glucose 6 phosphatase cannot dephosphorylate glucose 6 phosphate generated from liver glycogenolysis. As a result

Effects on health - consequences of air pollution, Effects on Health - Cons...

Effects on Health - Consequences of Air Pollution Since the air pollutants are inhaled they attack various parts of the respiratory system on their route to air sacs. Once the

What is polyembryony, Q. What is polyembryony? Polyembryony is the phen...

Q. What is polyembryony? Polyembryony is the phenomenon in which a single embryo in its initial embryonic stage divides itself forming many new individuals of genetically ident

Why the depicted food web is not complete, The depicted food web is not com...

The depicted food web is not complete, mainly because:  a. The number of producers is less than the number of consumers. b. There are no decomposers. c. Only secondary co

What are the substances that are constitute the chromatin, Q. What are the ...

Q. What are the substances that are constitute the chromatin? What is the difference between chromosome and chromatin? The chromatin, dispersed in the nucleus, is a set of fila

What carbohydrate characteristic chemical features include, Carbohydrate ch...

Carbohydrate characteristic chemical features include: Select one: a. the potential to form multiple hydrogen bonds. b. the existence of one or more asymmetric centers.

Why does thymine replace uracil in dna, Q. Why does thymine replace uracil ...

Q. Why does thymine replace uracil in DNA? The difference between DNA and RNA is existence of a hydroxyl (-OH) group on 2' carbon of the ribose sugar in the backbone. Removal o

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd