Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Explain digestion system, DIGESTION Digestive enzymes break down food p...

DIGESTION Digestive enzymes break down food particles into smaller units. You will see  that the final breakdown products of protein digestion are single amino acids or small c

Phylum protozoa, what are the classfication and members af phylum protozoa

what are the classfication and members af phylum protozoa

Explain delayed loading implant exposure, Q. Explain Delayed Loading Implan...

Q. Explain Delayed Loading Implant Exposure? The philosophy that has been described has its main objectives in the predictable achievement of osseointegration and the creation

Illustrate production of red blood cells, Q. What is the substance that sti...

Q. What is the substance that stimulates the production of red blood cells? Which is the organ that secretes it? Under what conditions does this secretion increase? The substan

Vitamins and minerals requirement in chronic diarrhoea, Q. Vitamins and min...

Q. Vitamins and minerals requirement in chronic diarrhoea? Loss of vitamins is related to the degree of mucosal damage in chronic diarrhoea, which in turn impairs absorption an

Define the parts of specific immune or defense mechanisms, The specific imm...

The specific immune (defense mechanisms) response can be broadly classified into two types: a)  Cell mediated immune response: This  is achieved through large number of acti

Blood pressure with the phenomena of systole and diastole, Q. What is the r...

Q. What is the relation between the maximum and the minimum blood pressure with the phenomena of systole and diastole? A minimum blood pressure is the pressure on the wall of t

Explain the bunsen burner, Explain the Bunsen Burner? It is a type of g...

Explain the Bunsen Burner? It is a type of gas burner that gives very hot flame by allowing air to enter at the base and mix with the gas. It is used - (a) For sterilizing i

Define regulation of water balance - for digestive process, Define Regulati...

Define Regulation of Water Balance - For the Digestive Process? For the digestive process alone, the estimated daily volume of fluid that enters and leaves the gastrointestinal

Proximal convoluted, Normal 0 false false false EN-IN ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd