Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Explain absorption and metabolism of minerals, Explain Absorption and Metab...

Explain Absorption and Metabolism of Minerals? All minerals in the diet are not equally absorbed. Also different compounds and complexes of same mineral are absorbed with diffe

What is the formation of atherosclerosis plaques, Which of the following le...

Which of the following leads to the formation of atherosclerosis plaques? -uptake of oxidized LDL particles by macrophase -non specific interactions between LDL particles

Define type of chemical reaction used in volumetric analysis, Define the Ty...

Define the Type of chemical reaction used in volumetric analysis? The titration has to be based on some rapid chemical reaction. Although any type of chemical reactions may be

What are the factors to measure such a prediction, You are interested in pl...

You are interested in plant life history evolution, you come across a population of the California poppy that i spolymorphic (mixed) for both iteroparous ans semeparous individuals

Protozoa, What are the disadvantages of protozoa

What are the disadvantages of protozoa

What is sustainability, What is sustainability? Sustainability is the a...

What is sustainability? Sustainability is the ability to meet human needsin a way that will allow a human population to survive indefinitely.

What would the result of a haploid egg, If a diploid sperm fertilized a hap...

If a diploid sperm fertilized a haploid egg, what would the result be? a.Haploid (n) b.Diploid (2n) c.A mixture of diploid (2n) and haploid (n) d.Triploid (3n)

What is supraventricular arrhythmias, Q. What is Supraventricular Arrhythmi...

Q. What is Supraventricular Arrhythmias? Such arrhythmia tend to be reduced by the vagal withdrawal accompanying the onset of exercise.This and wandering pacemakers tend to rec

Hormones secreted by pituitary gland, (a) Hormones of the Anterior lobe - ...

(a) Hormones of the Anterior lobe - The anteriorIobe of the pituitary gland secretes the following hormones, most of them are trophic hormones. (i ) Somatotropic hormone o

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd