Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Secretory proteins, Proteins destined to be secreted from the eukaryotic ce...

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is transloca

Retention of water by kidneys, Retention of water by the kidneys is regulat...

Retention of water by the kidneys is regulated by a part of the brain, called the hypothalamus, that controls the secretion of antidiuretic hormone (ADH).An increased secretion of

General guidelines of maintaining records of patients, General Guidelines ...

General Guidelines While working in the ward, you are always required to record. You should follow the general guidelines while recording which are as follows: All entri

Hetero trophic mode of nutrition, what is heterotroophic mode of nutrition?...

what is heterotroophic mode of nutrition?give some information about heterotrophic mode of nutrition?

How are the fruits formed, How are the fruits formed? The fecundation i...

How are the fruits formed? The fecundation is in angiosperms triggers the release of hormones that act upon the ovaries. The ovary wall after that it develops into a fruit that

Social health insurance systems, Normal 0 false false false...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

The wall of left ventricle of an infants heart, Because of developmental ab...

Because of developmental abnormality, the wall of left ventricle of an infant's heart is as thin as that of right ventricle. What would be its explicit effect on circulation of blo

Name the hormone that makes the plants more tolerant, In humans, starch dig...

In humans, starch digestion begins in the buccal cavity but stops in the Stomach. Why? Name the two most biodiversity-rich zones of India. Name the hormone that makes the p

Functions of insulin, Following are the functions of Insulin: 1) Insulin...

Following are the functions of Insulin: 1) Insulin controls the level of the sugar (glucose) in the blood. 2) Insulin permits cells to use sugar (glucose) for energy. Cells c

Clinical manifestations of infective endocarditis, Clinical Manifestations ...

Clinical Manifestations i) Evidence of Systemic Infection Fever, chills, rigor, night sweat, loss of weight, arthralgia, arthritis, backache, muscle pain.  ii) Ev

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd