Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Neurotransmitters to neuromuscular junctions, Blood functions to maintain h...

Blood functions to maintain homeostasis in the human body through all but which of the following: Answer moving carbon dioxide away from cells following completion of aerobic metab

Skeletal tissue - bone, BON E - Bone is the hardest tissue in the ...

BON E - Bone is the hardest tissue in the body and supports various organs. The inorganic salts present in the matrix are calcium phosphate, calcium carbonate, calci

Class of mollusca - monoplacophora, Class of Mollusca - Monoplacophora ...

Class of Mollusca - Monoplacophora Bilaterally symmetrical, with broad flat foot and single shell, mantle cavity has five to six pairs of gills; six pairs of nephridia of whi

A healthy potted pitcher plant, A healthy potted pitcher plant when kept in...

A healthy potted pitcher plant when kept in a green house with favourable conditions of light, temperature, soil and water showed poor growth although there was no infection. Give

Respiration in annelids, Describe the different types of respiratory organs...

Describe the different types of respiratory organs found in annelids.

Define the carbohydrate utilization pattern test, Define the Carbohydrate U...

Define the Carbohydrate Utilization Pattern Test? Carbohydrates are composed of carbon, hydrogen and oxygen. These organic molecules are catabolized by large number of microorg

Fdas post marketing surveillance system works, Problem 1: How does the ...

Problem 1: How does the FDA's post marketing surveillance system works? Show FDA's post marketing surveillance system Explain about Adverse Event reporting system and

What anatomical direction with respect to occipital cortex, The frontal cor...

The frontal cortex is in what anatomical direction with respect to the occipital cortex? a. anterior b. posterior c. sagittal d. inferior

Mechanism of maturation, Mechanism of Maturation The basic mechanism o...

Mechanism of Maturation The basic mechanism of maturation of ovum is more or less similar in all organisms. The primordial germ cells that enter into the ovary divide mitotica

What is the process of breathing, What is the process of Breathing? Oxy...

What is the process of Breathing? Oxygen is supplied to the blood, and carbon dioxide is removed from the blood by the process known as breathing. Air is moved into an exchan

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd