Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Subphylum uniramia, Subphylum Uniramia Uniramia, the largest subphylu...

Subphylum Uniramia Uniramia, the largest subphylum of phylum Arthropods includes myriapods and insects. Due to the unbranched nature of the appendages of its members, the sub

Describe class holothuroidea in details, Describe Class Holothuroidea in de...

Describe Class Holothuroidea in details? Members of this Class resemble soft and squishy cucumbers lying on their sides on the bottom of the sea. On first glance, they appear n

What is molecular weight, What is molecular weight? Molecular Weight ...

What is molecular weight? Molecular Weight :  The molecular weight of a molecule refers to the sum of the atomic weights of all the atoms making up the molecule. The gram mol

Simple proteins, SIMPL E PROTEINS The proteins are made of amino acids...

SIMPL E PROTEINS The proteins are made of amino acids only. Additional chemicals are absent. These are of two types -    (i) Fibrous        (ii) Globular ( i )

Body musculature - locomotion, Body Musculature - Locomotion The layou...

Body Musculature - Locomotion The layout of the muscle layers surrounding the coelom is necessarily the same in all the major classes of Annelida. The body wall has a layer of

Soil temperature, Soil Temperature Soil temperature is known to influe...

Soil Temperature Soil temperature is known to influence water absorption and ultimately transpiration to a considerable extent. In many plants water absorption is reduced shar

Explain the flow phase of stress response, Explain the Flow Phase of Stress...

Explain the Flow Phase of Stress Response? This is a neuro-endocrine response to physiological stress following the ebb phase. This phase is characterized by: Normal or

Phototropic curvature is the result of uneven distribution, Phototropic cur...

Phototropic curvature is the result of uneven distribution of : 1. Gibberellin 2. Phytochrome 3. Cytokinins 4. Auxin Auxin

Different modes of nutrition, Explain different modes nutrition like Autotr...

Explain different modes nutrition like Autotroph,hetrotroph,saprotroph,holozoic

Determine about the term - neuropsychology, Determine about the term - neur...

Determine about the term - neuropsychology The clinical practice of neuropsychology involves an integration of knowledge bases from the disciplines of psychology, psychometrics

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd