Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Hemoglobins - process of respiration, Hemoglobins - Process of Respiration ...

Hemoglobins - Process of Respiration Hemoglobins are the very well known of all respiratory pigments. The basic molecular unit of Hemoglobin contains a haem group bound to a

Carbohydrate required for underweight - nutritional care, Explain the Carbo...

Explain the Carbohydrate required for underweight - Nutritional Care? Liberal amounts of easy to digest carbohydrates should be included in the diet. The intake of dietary fibr

Describe the supra cardiac type of tapvc, Describe the Supra Cardiac Type o...

Describe the Supra Cardiac Type of TAPVC ? After connecting the baby to cnrdiopulmonary bypass, the common pulmonary venous channel is dissected. This lies behind the left atr

Define microscopical examination of starch granules, Define Microscopical E...

Define Microscopical Examination of Starch Granules? Take a slide and make a thin film of a suspension of starch granules from different sources and examine under a microscope.

Ancillary and sanitary accomodation, Ancillary Accomodation: Ward Kit...

Ancillary Accomodation: Ward KitchenIPantry:  It should have large sink and drain board along with fly proof door. If  the food is received from central kitchen and tray pre

Homo sapiens sapiens (modern man), Hom o sapiens sapiens (MODER N MA...

Hom o sapiens sapiens (MODER N MAN) - Developed from Cro-Magnon about 10,000 years ago after last glacial period in the regions of Caspian and Mediterranean seas.

What are the two divisions of the autonomic nervous system, Q. What are the...

Q. What are the two divisions of the autonomic nervous system? The autonomic nervous system is divided into the parasympathetic nervous system and the sympathetic nervous syste

Explain homologous and heterologous immunoglobulins, What is the difference...

What is the difference between homologous and heterologous immunoglobulins? Homologous immunoglobulin is the human (from the similar species) immunoglobulin. In case of inocula

.photosynthesis, what additional substance does a plant need to male amino ...

what additional substance does a plant need to male amino acids and proteins from glucose

Canine distemper, Canine distemper Canine distemper, a highly contagio...

Canine distemper Canine distemper, a highly contagious disease of dogs, is caused primarily by air- borne virus which belongs to the genus Morbillivirus in family Paramyxoviri

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd