Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Explain disease motion sickness, Motion Sickness  The pathogenesis of m...

Motion Sickness  The pathogenesis of motion sickness is poorly under- stood. The prescription cholinergic blocker scopolamine in a patch or oral formulation can decrease sympto

Define single beam and double beam optical path, Define Single Beam and Dou...

Define Single Beam and Double Beam Optical Path? In simpler instruments, a single beam of light passes through the cuvettes and reaches the detector whereas in the double beam

What is insect killing jar, Insect killing jar Secure a wide-mouth glas...

Insect killing jar Secure a wide-mouth glass jar with a screw top or single which closes very tightly. Place a wad of cotton in the bottom and cover it with a round piece of ca

Pseudopodia – protozoans, Pseudopodia – Protozoans Pseudopodia are flo...

Pseudopodia – Protozoans Pseudopodia are flowing cytoplasmic protrusions of the cell causing amoeboid movement. In protozoans pseudopodia exist in several forms. The most fami

Define determinants of food security - food access, Define Determinants of ...

Define Determinants of Food Security - Food Access? Food access is linked to its affordability. Food access is ensured when households and all individuals within them have adeq

Agro industrial-enrichment of soil, Enrichment of soil Indirect provis...

Enrichment of soil Indirect provision of minerals to grazing livestock includes mineral fertilization of  pasture and altering soil pH, however this may not be always feasible

Physical concepts of plant water relation - diffusion, Physical Concepts of...

Physical Concepts of Plant Water Relation - Diffusion Diffusion is a spontaneous process that leads to net movement of a substance from a region of higher concentration to a r

Closed heart surgery, Closed Heart Surgery Blind operations and access...

Closed Heart Surgery Blind operations and access is obtained into the heart through incision on the ventricular or atrial wall. Commonest closed heart surgery done is m

Oogenesis., write breif notes on oogenesis

write breif notes on oogenesis

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd