Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

What is the phase of the menstrual cycle, Q. In general what is the phase o...

Q. In general what is the phase of the menstrual cycle when copulation may lead to fecundation? Although this is not a rule, to be effective fecundation in general must occur w

Genotype for each individual, The allele that causes albinism (p) is recess...

The allele that causes albinism (p) is recessive to the allele for normal pigmentation (P). A normal woman whose father is an albino marries an albino man whose parents are both no

What are the genotype and phenotype of the unknown male, For Dalmation dog,...

For Dalmation dog, the spotted condition is dominant to non-spotted. a) Using a Punnet square, show a cross between two heterozygous parents. b) A spotted female Dalmation dog is m

How would contrast single covalent bonds, 1. In modern blimps, the gas of c...

1. In modern blimps, the gas of choice used to inflate them is helium rather than hydrogen. Hydrogen would be lighter, but helium is safer. Compare and contrast the atomic structur

Explain the micronutrients requirements during sepsis, Explain the Micronut...

Explain the Micronutrients Requirements during Sepsis Micronutrients: The requirement of almost all vitamins and certain mineral increases due to infection and inflammation. In

Hypoglycaemic treatment, Hypoglycaemic coma is a medical emergency. A loss ...

Hypoglycaemic coma is a medical emergency. A loss of consciousness is due to low sugar level. Patient should immediately be given biscuits, chocolates, sweet, fruit. If unconscious

Taxonomic key, I need help with making a taxonomic key

I need help with making a taxonomic key

Starr-edward silastic ball valve prosthesis-types of valves, Starr-Edward ...

Starr-Edward (S-E) Silastic Ball Valve Prosthesis : This was introduced in 1961 by Albert Stm and has different models for mitral and aortic positions. It is a cage and b

Define the utilization of most probable number techniques, Define the Utili...

Define the Utilization of Most Probable Number Techniques? The MPN technique (multiple tube technique) can be used to determine the presumptive coliform count in the food. The

Discuss various methods of dry heat sterilization, Question 1 List the dif...

Question 1 List the differential staining techniques used in microbiology laboratory. Explain Gram staining technique in detail. Add a note on modifications of Gram staining and a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd