Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Disorder of adrenal function, Disorder  of Adrenal Function: The diso...

Disorder  of Adrenal Function: The disorders of  adrenal function may lead  to acute and chronic  .adrenocortical insufficiency. Let  us briefly  describe each  one as follows

Is reproduction in sponges asexual or sexual, Q. Is reproduction in sponges...

Q. Is reproduction in sponges asexual or sexual? Reproduction in sponges can be asexual by budding, fragmentation or gemmation (regeneration) or sexual with larval stage a cili

Mountain forest ecosystem as life support systems, Mountains and their fore...

Mountains and their forest ecosystems are regarded as the water towers of the world. A good example is the extraordinarily massive Himalayan Mountains which have shaped the climate

Pollination, Pollination Many flowering plants rely on animals such as b...

Pollination Many flowering plants rely on animals such as bees, butterflies, moths, wasps, beetles, birds, and bats for pollination to produce fruit. Thirty percent of our food

Which kind of circulatory system do molluscs have, Q. Which kind of circula...

Q. Which kind of circulatory system do molluscs have? How can it be compared to the respiratory system of annelids? Molluscs, with the exception of cephalopods, have an open ci

Incomplete digestive and a complete digestive system system, Q What is the ...

Q What is the difference between an incomplete digestive and a complete digestive system system? How are these types of digestive tubes associated or not to extracellular digestion

What is sodium bicarbonate, What is Sodium Bicarbonate? The administrat...

What is Sodium Bicarbonate? The administration of bicarbonate may be considered if the pH remains below 7.1 or if hyperkalemia or tricyclic antidepressant overdose is suspected

Can a chemical reaction the free energy change to mol, In a chemical reacti...

In a chemical reaction the free energy change (/\Go') is -40 jk/mol and the entropy factor T/\S is 15 kj/mol. the enthalpy change /\H for the reaction is a. 25 kj/mol b.-25 k

Two traits are involved in a genetic cross, In his experiments, Mendel note...

In his experiments, Mendel noted that when two traits are involved in a genetic cross, they are inherited independently of each other. The reason for this is that A. genes on the s

Lymphatic vessels, Lymphatic Vessels The function of lymphatic vessel...

Lymphatic Vessels The function of lymphatic vessels is to aid in the return of interstitial fluid to intra-vascular volume. They assist with transport of lipids from th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd