Thalassemia, Biology

Assignment Help:

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  


Related Discussions:- Thalassemia

Bones, which bone forms the non-moving muscle attachment in the hip joint

which bone forms the non-moving muscle attachment in the hip joint

Name the classes of biomaterials, Explain the classes of biomaterials W...

Explain the classes of biomaterials When an artificial material is placed in the human body, tissue reacts in a variety of ways depending on the material type thereby, affectin

Structures in the Dermis, list of the structures you would expect to find i...

list of the structures you would expect to find in the dermis.

Cells, List structures found in unicellular organisms that are an adaptatio...

List structures found in unicellular organisms that are an adaptation to their free-living life and are not usually found in the cells of multicellular organisms.

How does the inflammation mechanism work, Q. How does the inflammation mech...

Q. How does the inflammation mechanism work? When some tissue injury other vasoactive and occurs histamine substances (called mediators of inflammation) are released, they caus

Hypocoagulation disorder and vitamin k deficiency, Which of the following p...

Which of the following patients likely faces the highest risk of an acquired hypocoagulation disorder and vitamin K deficiency? Answer A. A patient who is immunocompromised as a re

Horse diseases-equine viral arteritis, Equine viral arteritis Equine v...

Equine viral arteritis Equine viral arteritis (EVA) is a highly contagious disease of equines and is caused by equine arteritis virus (EAV), a RNA virus belonging to the genus

Define method for radiographic evaluation of the outcome, Method for Radiog...

Method for Radiographic evaluation of the outcome or RCT Ørstavik and associates suggest the use of the periapical index (PAI) for radiographic evaluation of the outcome of roo

Determine about the diseases sleep attacks, Determine about the diseases Sl...

Determine about the diseases Sleep attacks These are brief, often irresistible, episodes of sleep, probably slow wave, NREM, naplike sleep that last about 15 minutes and can oc

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd