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The original DNA sequence when ,transcribed and translated would yield five successive valine residues. But the altered sequence would correspondingly read one aspartate and four serine residues. Mutations resulting from the addition or deletion of base pairs are called frameshift mutations. So far we have discussed the several ways in which the genetic material could be altered. Mutations could be either spontaneous or induced. In recent years there has been a more clear understanding of the causes of mutational process. Tautomeric shifts, ultraviolet radiations, chemicals such as hydroxylarnine, nitrous acid and a variety of alkylating agents can cause permanent alterations of nitrogenous bases. Aromatic compounds such as acridines can cause addition or deletion of one to more than twenty bases in DNA. We have briefly discussed mutations, a way or source of variability in natural populations. Together with recombinations occurring'at the tjnie of meiosis they form the raw materials for selection to act on. Before we discuss briefly about recombination, let us have a quick look at mutation rates in organisms.
Explain the Bioavailability of Thiamin? Thiamin is readily available from the gut from food sources (as thiamin phosphate esters). Drugs and alcohol abuse may interfere with th
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Why can it be said that a recessive allele can remain hidden in the phenotype of an individual and revealed only when manifested in homozygosity in the offspring? A recessive a
Availability of ADP When the ADP levels increase due to hydrolysis ofATP in various biosynthetic reactions, the rate of reaction to generate ATP is accelerated and this i
Define Isotope Dilution Method? The measurement of total body water (TBW) is based on the principle of hydrometry. You must be aware that water is the most abundant substance i
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Barriers to Fertilisation Incompatibility can occur anywhere from pollination to syngamy and consequently obstructing fertilisation. The pollen fails to germinate or the polle
Define Food Sources of Calcium? Dairy products are of course the primary source of calcium followed by grains and pulses. Among the millets, ragi contains substantial amount of
The agouti locus in mice has three alleles: A is recessive and confers a black coat, A is dominant to a and confers an agouti coat, and AY is dominant to both and confers a yellow
a) A cat has just arrived to the veterinary clinic with low blood pressure. The cat weighs 5 kg, and as the on call Vet you want to use a bag of saline to prepare a dopamine drip f
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