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The original DNA sequence when ,transcribed and translated would yield five successive valine residues. But the altered sequence would correspondingly read one aspartate and four serine residues. Mutations resulting from the addition or deletion of base pairs are called frameshift mutations. So far we have discussed the several ways in which the genetic material could be altered. Mutations could be either spontaneous or induced. In recent years there has been a more clear understanding of the causes of mutational process. Tautomeric shifts, ultraviolet radiations, chemicals such as hydroxylarnine, nitrous acid and a variety of alkylating agents can cause permanent alterations of nitrogenous bases. Aromatic compounds such as acridines can cause addition or deletion of one to more than twenty bases in DNA. We have briefly discussed mutations, a way or source of variability in natural populations. Together with recombinations occurring'at the tjnie of meiosis they form the raw materials for selection to act on. Before we discuss briefly about recombination, let us have a quick look at mutation rates in organisms.
Determine the Fransworth 100 Hue Panel Test This is a simple and useful test using colour chips arranged in a particular sequence. Colour deficient patients make errors in arra
Zone of Polarizing Activity (ZPA) The A-P axis is the 1 st axis to be fixed in the presumptive limb mesoderm at a very early stage. On the basis of results of a series of cur
activity
Explain Interaction of pyridoxine with Carbohydrates? Pyridoxine is involved in glyconeogenesis through its action in transaminase reactions. Low levels of pyridoxine impair gl
Give the introduction to Cardiac rehabilitation? Cardiac rehabilitation services are comprehensive, long-term programs involving medical evaluation, prescribed exercise, cardia
Antibodies Antibodies are important.tools for detecting and localising specific molecules in the cells due to their high specificity. The first requirement for this is to produ
Explain the different types of cells in cell structure ? Types of Cells : Cells can be classified as being either prokaryotic or eukaryotic depending on whether or not a mem
what is skeleton?
What is Prokaryotic Gene Expression ? Control of prokaryotic gene expression occurs primarily at the level of transcription. Prokaryotic genes are arranged in units consisting
Explain the Liver Biopsy Assays? These are used to measure the total vitamin A stores, as well us, the response in levels of vitamin A relative to different dosages of the vita
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