Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Difference between spermatid and spermatocyte ii, Q. What is the difference...

Q. What is the difference between spermatid and spermatocyte II? The spermatids (n) are the products of the second division of meiosis (meiosis II) in the male gametogenesis an

How to use atp to make reactions go, What do enzymes do, and how? How is en...

What do enzymes do, and how? How is enzyme activity regulated in cells? How do ATPases u se ATP to make reactions go?

Define age as a determinants of nutrient requirements, Define Age as a dete...

Define Age as a determinants of nutrient requirements? Age: Requirements change with increasing age between birth and maturity. Nutrient requirements per unit body weight are h

Explain the human body system and organs, Body systems and organs and their...

Body systems and organs and their functions The human body is a large structural unit made up of many smaller parts. There are four kinds of smaller units - cells, tissues, org

Golgi apparatus, GOLGI APPARATUS Camillo Golgi in 1898 discovered a retic...

GOLGI APPARATUS Camillo Golgi in 1898 discovered a reticular structure in the cytoplasm of nerve cells with the help of metal impregnation technique using silver nitrate for whic

Egestion, After the food intake is over, the food gets digested, assimilate...

After the food intake is over, the food gets digested, assimilated and finally egested through the kidneys and anus. The urinary system: • Filters waste materials from the blood

Describe in detail about the huntington''s disease, Describe in detail abou...

Describe in detail about the Huntington's disease The brain of a person who has died as a result of Huntington's disease or Alzheimer's disease will look abnormal even to the

Explain about the weight imbalance, Explain about the Weight Imbalance? ...

Explain about the Weight Imbalance? You are aware that obesity is one of the major public health problems of the world, Earlier a problem of the developed nations; it is now in

Explain about microbial polysaccharides, Microbial polysaccharides Many...

Microbial polysaccharides Many microorganisms produce polysaccharides that either remain attached to the cell wall (capsular polysaccharides) or are  secreted into the extracel

Determine guidelines to lower risk and wise use of drugs, Determine Guideli...

Determine Guidelines to Lower Risk and Wise Use of Drugs? There can be no two views regarding the act that the management of many diseases require drug therapy. However, they m

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd