Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

What are the main types of cancer that affect humans, Q. What are the main ...

Q. What are the main types of cancer that affect humans? An Excluding skin cancer, that are the more easily detected and so cases are registered in larger number, the main type

What are the main constituents of the earth atmosphere, What are the main c...

What are the main constituents of the earth's atmosphere in our time? The present atmosphere of the earth is constituted mostly of molecular nitrogen (N2) and molecular oxygen

Illustrate about the complex partial seizures, State about the Complex part...

State about the Complex partial seizures Complex partial seizures, another type of focal seizure, originate most commonly in the temporal lobe. Complex partial seizures are cha

Rassenkreis and speciation, According to the current concept of speciation,...

According to the current concept of speciation, a widely distributed species should break up into partially isolated rule species. The different subspecies become differentiated fu

What is population density, Q. What is population density? The Populati...

Q. What is population density? The Population density is the relation between the number of individuals of a population and the area or volume they occupy. For instance, in 200

Why influenza activity is mandatory in the united states, Healthcare provid...

Healthcare provider reporting of influenza activity is mandatory in the United States.

What is connective tissue proper, What is connective tissue proper? The...

What is connective tissue proper? The name connective tissue proper is used to assign the connective tissue that fills interstitial spaces as opposed to the specialized connect

Classification scheme of protozoa, Classification Scheme of Protozoa ...

Classification Scheme of Protozoa Phylum Myxozoa Parasites of lower vertebrates especially fish and invertebrates. Phylum Microspora Parasites of inv

What are muscle tissues, What are muscle tissues? How is the function of th...

What are muscle tissues? How is the function of this tissue related to the typical characteristics of its cells? Muscle tissues are tissues made of cells able to perform contr

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd