Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Explain the development of cancer, Explain the Development of Cancer? A...

Explain the Development of Cancer? Are you interested in knowing how cancer develops? Well here it is. The cancer development is a process involving initiation, promotion and p

What are the dietary guidelines for gastritis, Q. What are the dietary guid...

Q. What are the dietary guidelines for gastritis? Energy: Give adequate calories through frequent feedings or else proteins would be utilized for energy of repair work. P

Concerning the number of hosts how are parasites classified, Q. Concerning ...

Q. Concerning the number of hosts how are parasites classified? The Parasites that require only one host are called as monoxenous parasites. The Parasites that need more than o

What do digestive enzymes do to food, What do digestive enzymes do to food?...

What do digestive enzymes do to food? Digestive enzymes suspend food; make food soluble, break large insoluble food molecules into smaller, soluble molecules

Scentific american article suggests some improvements, The human skeleton h...

The human skeleton has evolved from that of four-legged animals. Unfortunately, the adaptation is far from perfect; thus, our upright posture causes problems like backage and the k

What are the indications of cardiac transplantation, What are the indicatio...

What are the indications of Cardiac Transplantation ? Indication :  Patients in NYHA class IV with heart failure, refractory to medical management caused by end stage corona

Explain other lipids in biological compound, Explain Other lipids in biolog...

Explain Other lipids in biological compound? Other Lipids :  Another important type of lipids are the steroids, with a basic structure consisting of four interconnecting carb

Explain the numerical taxonomy, Explain the Numerical Taxonomy? Numeric...

Explain the Numerical Taxonomy? Numerical methods in taxonomy are not new. Simple statistical methods like standard deviations, t-tests and chi-squared have been used for sever

What are the approaches to the design of retaining walls, What are the appr...

What are the approaches to the design of retaining walls? The approach to the design of retaining walls can be started as follows: a. Chosse a trial dimension of the wall

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd