Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Rapport building of counselling process of diabetic patient, Q. Rapport Bui...

Q. Rapport Building of Counselling process of diabetic patient? 1. Rapport Building - Introduce yourself to the counsellee. - Get the introduction of counsellee. - Sit

Life style modification in management of diabetes mellitus, Life style modi...

Life style modification in the management of diabetes mellitus All of us have our own way of living. It becomes a routine when we do things in the same way. But when one falls

Single pair of alleles, Give three examples of human disorders which are ca...

Give three examples of human disorders which are caused by the action of a single pair of alleles. In every case say whether the harmful allele is dominant or recessive to the non-

Define poverty and ignorance - cause of anaemia is dietary, Define Poverty ...

Define Poverty and ignorance - cause of anaemia is dietary? Low purchasing power of the communities and their consequent inability to meet the nutrient requirements, even after

Epithelial Cells, What are all teh parts of a simple ciliated columnar epit...

What are all teh parts of a simple ciliated columnar epithilial cell?

Blood formation, why are blood formed at bones or joints

why are blood formed at bones or joints

Show water permeability of the luminal membranes, Healthy Person H takes a ...

Healthy Person H takes a new drug named ANTICAMPCOLLDUCT that blocks the production of cyclic AMP (cAMP) in collecting duct epithelial cells in response to vasopressin binding to V

Genetics, Considering a pair of homologous chromosomes containing a gene ha...

Considering a pair of homologous chromosomes containing a gene having two different alleles how many different genotypes can the individual present?

Nutrition, The oxidation of sugar in the cell of higher organisms takes pla...

The oxidation of sugar in the cell of higher organisms takes place in the ?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd