Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Determine the organs of female reproductive system, What are the anatomical...

What are the anatomical relationships between the organs of the female reproductive system from the external vulva to the ovaries? The external female genitalia is called the v

Explain the compartments of body water, Explain the Compartments of Body Wa...

Explain the Compartments of Body Water? Within the body, water is found in two major compartments. These are: - The intracellular compartment (inside the cell) - The extr

Explain surlyn film, Q. Explain Surlyn film? Surlyn films: Surlyn (SU) ...

Q. Explain Surlyn film? Surlyn films: Surlyn (SU) is a versatile film which is sometimes favoured over polyethylene due to some unique properties such as excellent moisture b

Describe in detail - nacreous layer., Describe in detail - Nacreous layer. ...

Describe in detail - Nacreous layer. The innermost of the three layers of a mollusc shell. It is also referred to as mother-of-pearl, it comprises thin layers or calcium carbon

Modern infection control recommendations, Q. Modern infection control recom...

Q. Modern infection control recommendations? Concern about transmission of disease has been expressed for thousand of years. Written guidelines for "disease control" are found

Introduction to transgenic animals, Transgenic Animal Over the centurie...

Transgenic Animal Over the centuries, animals with new combinations of genes have been produced using conventional breeding methods by means of careful selection of particular

Levels of biodiversity, There are three levels of diversity viz. genetic, ...

There are three levels of diversity viz. genetic, species and ecosystem diversity. In effect, these levels cannot be separated. Each is important, interacting with a nd influencin

What are the three major types of passive transport, Q. What are the three ...

Q. What are the three major types of passive transport? The three main types of passive transport are simple osmosis, diffusion and facilitated diffusion.

Dry stigma - category of stigma, Dry Stigma - Category of Stigma The C...

Dry Stigma - Category of Stigma The Cotton (Gossypium hirsutum) stigma is covered with long unicellular hairs. At the time of pollination, the stigmatic hairs show a distinct

Wbcs types, mode of action of wbcs types

mode of action of wbcs types

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd