Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

The genetic code is degenerate, Because RNA is composed  of four parts of n...

Because RNA is composed  of four parts of nucleotides,  there are 43 =  64 possible codons,  which  is  64  possible  triplets  of  nucleotides   with  several  sequences. Furtherm

What are the major cellular features of fungi, Q. What are the major cellul...

Q. What are the major cellular features of fungi? There are pluricellular and unicellular fungi. All fungi are heterotrophs and eukaryotes. Fungi have cells with cell wall m

Pulsatile perfusion-type of blood pump, Pulsatile Perfusion: Conventional...

Pulsatile Perfusion: Conventional pumps give continuous flow with very little pulsatile property. Pulsatile perfusion is likely to result in better post operative renal and cardi

Polymerase chain reaction, The PCR (polymerase chain reaction) is a biochem...

The PCR (polymerase chain reaction) is a biochemical technology in molecular biology to intensify a one or a little copies of a piece of DNA across several orders of magnitude gene

What are the endocrine functions of the placenta, What are the endocrine fu...

What are the endocrine functions of the placenta? The placenta has endocrine function since it secretes the hormones progesterone and estrogen that maintain the endometrium (in

Unitary explanation for protein synthesis, Q. Why is the concept of a singl...

Q. Why is the concept of a single gene as ultimateunit of inheritance inadequate to provide a unitary explanation for protein synthesis, recombination and mutation? Answer:

Describe what types of results describe hypothesis, Why did giraffes develo...

Why did giraffes develop long necks? 1) Describe an experiment to test this hypothesis. Be explicit about the methods you will use, the setting, the time that the experiment wil

Amoeboid movement, Normal 0 false false false EN-IN X...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Glucagon and glucocorticoids, Important  aspects  related to regulation inc...

Important  aspects  related to regulation include: 1)  The hormones glucagon and glucocorticoids  which are  secreted  during  starvation stimulate  glucose-6-phosphatase to en

Which are the 2 main divisions of autonomic nervous system, Question 1....

Question 1. Which are the 3 different processes in the formation of urine? Explain 2. Discuss resting membrane potential and nerve action potential 3. Name the chemical s

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd