Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Which of mendel''s postulates demonstrated in crosses, Which of Mendel's po...

Which of Mendel's postulates can only be demonstrated in crosses involving at least two pairs of traits? a) Segregation b) dominance/recessiveness c) independent assortment d) unit

What is self-jamming, What is Self-jamming Unless all of the mobile cli...

What is Self-jamming Unless all of the mobile client are perfectly synchronized, the arriving transmissions from multiple clients will not be perfectly aligned on chip boundari

Coronary flow limiting stenoses, Coronary Vasoconstriction 1) Coronary f...

Coronary Vasoconstriction 1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor change

What is packaging, Q. What is packaging? What is packaging? Packaging...

Q. What is packaging? What is packaging? Packaging means a coordinated system of preparation of goods (in this case, foods) for shipment, distribution, storage and

What are the functions of polypeptide chains, Q. Since among the 64 codons ...

Q. Since among the 64 codons of mRNA 61 codify amino acids that form polypeptide chains what are the functions of the three remaining codons? Since there are 20 amino acids and

Portion of double-stranded dna, Suppose that a portion of double-stranded D...

Suppose that a portion of double-stranded DNA in the middle of a large gene is being transcribed by an RNA polymerase. As the polymerase moves through the sequence of six bases sho

Development and differentiation of a flowering plant, Development and Diffe...

Development and Differentiation of a flowering plant The developmental phases of a flowering plant involve seed germination, vegetative growth, flowering, fruiting and senesce

Name the foods allowed in soft diet, Which Foods allowed in soft diet:- ...

Which Foods allowed in soft diet:- Soups - mildly flavoured -  broths and cream soups. Beverages -  all Meat -  moist, tender meat, fish or chicken, cottage cheese, eggs

Explain the primary stain - ziehl-neelsen method, Explain the Primary Stain...

Explain the Primary Stain - Ziehl-Neelsen Method? Ordinary aqueous stains like methylene blue, crystal violet, etc. are not able to stain most of the species of Mycobacteria. C

What is meningitis, Q. What is meningitis? The Meningitis is the generi...

Q. What is meningitis? The Meningitis is the generic name given to inflammation of the meninges and membranes that cover the central nervous system. The Meningitis can have sev

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd