Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

State the jackson coleman and fischer theory, Jackson Coleman and Fischer T...

Jackson Coleman and Fischer Theory Jackson Coleman Theory: During accommodation the ciliary muscle contraction causes an anterior thrust of the vitreous. This vitreous thrust p

Explain tropical rain forests in biomes, Explain Tropical Rain Forests in b...

Explain Tropical Rain Forests in biomes? You probably are well aware of the danger that the world's rain forests are facing in terms of extinction! There are huge numbers of sp

Dna structure, A)Which of the following statements about DNA structure is t...

A)Which of the following statements about DNA structure is true? 1.The nucleic acid strands in a DNA molecule are oriented ant parallel to each other, meaning they run in opposite

What is the production of rna called, What is the production of RNA called ...

What is the production of RNA called and what is the enzyme that catalyzes the process? The making of RNA from information included in DNA is called transcription. The enzyme t

Importance of biodiversity, T hese are some important uses of biodiversity....

T hese are some important uses of biodiversity. 1.   Source of food, medicines and drugs: (a)       Wheat, rice and maize are three carbohydrate rich crops and contribute

Illustrate glycolysis within the mitochondria, Q. Does glycolysis take plac...

Q. Does glycolysis take place within the mitochondria? Glycolysis happens in the cytosol and not in the mitochondria. Pyruvic acid molecules later enter mitochondria to partici

Illustrate production of red blood cells, Q. What is the substance that sti...

Q. What is the substance that stimulates the production of red blood cells? Which is the organ that secretes it? Under what conditions does this secretion increase? The substan

Preserving foods, One of man's oldest methods of preserving foods is drying...

One of man's oldest methods of preserving foods is drying or desiccation. The preservation of foods by drying is a direct result of removal of moisture. Microorganisms need water

Explain fomivirsen, Explain Fomivirsen  Fomivirsen, an  antisense olig...

Explain Fomivirsen  Fomivirsen, an  antisense oligonu- cleotide, is FDA-approved for intravitreal treatment of CMV retinitis in HIV-infected patients who cannot tolerate or ha

What are the disadvantages of ridgemapping, Disadvantages of Ridgemapping ...

Disadvantages of Ridgemapping  a) Traumatic procedure b) Time consuming procedure and needs more armamentarium c)  There is an inherent risk of inaccuracy especially whil

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd