Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Explain the regulation of blood glucose concentration, Explain the Regulati...

Explain the Regulation of Blood Glucose Concentration? A number of mechanisms function to maintain blood glucose at remarkably constant level of 70-100 mg/dl under fasting cond

Explain about the insulin syringe, Insulin Syringe To administer Insuli...

Insulin Syringe To administer Insulin properly, familiarize yourself with information about insulin: (a) insulin syringes, (b) storage, (c) site selection (d) steps for injecti

Define biodiversity and ecosystem stability, Define Biodiversity and ecosys...

Define Biodiversity and ecosystem stability? Human's have transformed ecosystems all through the world, frequently replacing diverse natural ecosystems with ecosystems which ar

What is acute severe mitral regurgitation, Q. What is Acute Severe Mitral R...

Q. What is Acute Severe Mitral Regurgitation? Acute severe mitral regurgitation is a medical emergency. Patient presents with breathlessness and low output state. He may be is

Thermodynamics, Thermodynamics Thermodynamics  tells us that every tran...

Thermodynamics Thermodynamics  tells us that every transformation of matter chemical  transformation is  accompanied with  energy conversion .For example  when complex  molecul

What is electro osmosis , What is Electro osmosis ? Electro osmosis :...

What is Electro osmosis ? Electro osmosis :  Electroosmosis is the movement of charged molecules along a charged surfaces in response to a voltage difference. For example, e

Zoology, Classification of the Phylum Protozoa up to orders

Classification of the Phylum Protozoa up to orders

Behavioural adjustments, Behavioural Adjustments When faced with a su...

Behavioural Adjustments When faced with a sudden temperature change, most animals make behavioural responses that enable them to avoid extreme or lethal conditions. Among the

Explain food applications of dextran, Food Applications Dextran can be ...

Food Applications Dextran can be used in food products, as it is capable of moisture retention and inhibition of crystallization of sugar. The properties of dextran as gelling

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd