Supportive evidence - erythema marginatum, Biology

Assignment Help:

Minor Criteria

These are arthralgia, fever, prolonged PR interval, raised ESR and C-reactive protein levels. In some cases abdominal pain and epistaxis may occur. Other non specific laboratory findings are leucocytosis and anaemia.

Supportive Evidence

One must always look for supportive evidence for antecedent GAS infection in form of positive throat culture, rising ASO titres, and rapid streptococcal antigen tests.  Various antibody tests carried out are anti-streptolysin O, anti-deoxyribonuclease B (ADNaseB), anti-nicotinamide adenosine dinucleotidase (ANA Dase), anti-hyaluronidase and anti-streptokinase.

When two serum samples taken at 2-4 weeks intervals show a two-fold rise, antibody tests are considered positive. The ASO titres of > 250 Todd units in adults and > 333 Todd Units in children are considered positive. The ASO titres may take upto 4-6 months to return to normal, hence by the time chorea or carditis develops after ARF, ASO titres may have returned to normal. In such situation, one may rely on ADNase B levels, as it remains elevated even beyond 6 months after ARF. Diagnosis of ARF is confirmed if 2 major or one major and 2 minor Jones criteria are present along with a supporting evidence of GAS pharyngitis.


Related Discussions:- Supportive evidence - erythema marginatum

Photoperiodism was first characterised, Photoperiodism was first characteri...

Photoperiodism was first characterised in : 1. Tobacco 2. Potato 3. Tomato 4. Cotton Tobacco is the first in whic photoperiodism characterised.

Properties of transparency factors in corneal hydration, What are special p...

What are special properties of transparency factors in corneal hydration of cornea? The factors affecting the transparency include special properties of the corneal epitheliu

Multicausal nature of cancer, Multicausal Nature of Cancer With sever...

Multicausal Nature of Cancer With several dividing cells in the organism and the various proto-oncogenes and tumor suppressor genes that can be changed to cause cancer. one m

Phylum cnidaria (coelenterata ), PHYLUM  CNIDARIA (= COELENTERATA )       ...

PHYLUM  CNIDARIA (= COELENTERATA )         Definition and Introduction Tissue  grade eumetazoans with  a radial  symmetry .The  term  coelenterate  signifies the  presence

Viruses.., are there non-parasitic viruses

are there non-parasitic viruses

Explain the effect on vitamins of the human milk, Explain the effect on Vit...

Explain the effect on Vitamins of the human milk? Although there are inter-individual variations in vitamin concentrations, diet and drug use by individual women influences vit

Hemicellulose, HEMICELLULOSE It consists of mannose, galactose, arab...

HEMICELLULOSE It consists of mannose, galactose, arabinose & xylose. It is a structural polysaccharide which helps in formation of cell wall. Maximum quantity of hemic

Explain understanding the response of farmers, Explain Understanding the re...

Explain Understanding the response of farmers? Understanding the response of the farmers by the government also influences the food production. Government policy influences the

In which lysosomic enzymes play a fundamental role, Q. What are the various...

Q. What are the various biological examples in which lysosomic enzymes play a fundamental role? The remodelation of the osseous tissue, the function of the elimination of the t

Explain doctrine of signatures, Explain Doctrine of Signatures? Handed ...

Explain Doctrine of Signatures? Handed down from the ancients, and elaborated on by the herbalists, was the 'Doctrine of Signatures', which was based on features that resembled

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd