Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Steroid and Thyroid Hormones
Cytoplasmic receptors for steroids are proteins with two subunits that bind to the steroid molecules. When both receptor sites are occupied by the steroid then the receptor-steroid complex migrates to the nucleus where one subunit ensures that the complex binds to the specific site on the chromatin. Then the receptor subunits separate and the other subunit interact directly with the adjacent region of DNA molecule resulting in the transcription of the DNA segment into mRNA.
Thyroid hormone acts in a similar manner except that the receptor is located in the nucleus. The major hormone secreted by thyroid is thyroxine (T4). It travels in blood attached to carrier proteins. Thyroid also secretes a small amount of triiodothyronine (T3). Carrier proteins have higher affinity for T4 and very little T4 is free in the plasma. Only the free T4 and T3 enter the cells. The rest of the bound T4 acts as a reservoir for slow release. The free T4 that enters the cell s also converted to T3 enzymatically. Therefore, T3 is the chemically more potent and active form of thyroid hormone.
Figure:Steroid and Thyroid Hormones
The Km for an enzyme A. is equal to kcat, measured at low substrate concentration. B. is the substrate concentration that gives a velocity that is half the maximum velocity.
Relate the oxide layer and biocompatibility of titanium. The compatibility of a metal with its host environment depends on its resistance to biodegradation and on the degree of
Lipid profile control Evaluation of lipid profile is essential to the management of diabetes and should be performed at initial visit in all patients with diabetes. You have l
An account of characters of mollusca
Coo k in g loss and quality Yields and cooking losses of products are important as these determine acceptability and economics of products. Higher cooking losses increase th
Which type of tissue are the cartilaginous and the osseous tissue? The cartilaginous and the osseous tissues are considered connective tissues as they are tissues in which the
Enterocoelous pattern – Coelom In enterocoelous development of coelom the mesoderm arises in the embryo as paired lateral pouches growing out from the archenteron. The pouche
Economic Biology: This is the study of useful plants and animals or their products. Economic biology is referred to as economics and human biology. Economics or Human Biology can
Use of Beta-blockers : In some centres, patients are routinely put on beta-blockers after CABG. European coronary artery surgery study showed that only 25 per cent of patient
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd