Splenic abscess, Biology

Assignment Help:

Splenic infarction is a common complication of left-sided IE (40 per cent of cases). Only 5 per cent of patients with splenic infarction will develop splenic abscess. This infection develops via 1 of 2 mechanisms Bacteremic seeding of a bland infarction, created via splenic artery occlusion by embolized vegetations, or direct seeding of the spleen by an infected embolus also originating from an infected valvular vegetation. Viridans streptococci and S aureus each account for 40 per cent of cases in which splenic abscess cultures are positive, whereas the enterococci account for 15 per cent of cases. Aerobic Gram-negative bacilli and fungi are isolated in, 5 per cent of cases. Clinical splenomegaly, present in up to 30 per cent of cases of IE, is not a reliable sign of splenic infarction or abscess. Splenic infarction delineated by imaging techniques is often asymptomatic Back, left-flank, or left-upper-quadrant pain or abdominal tenderness, when present, may be associated with either splenic infarction or abscess. Splenic rupture with hemorrhage is a rare complication of infarction. Persistent or recurrent bacteremia, persistent fever, or other signs of sepsis are suggestive of splenic abscess, Abdominal CT or MRI appear to be the best tests for diagnosis of splenic abscess, with sensitivities and specificities of 90 per cent to 95 per cent. On ultrasonography, a sonolucent lesion suggests abscess. Infarcts are generally associated with clinical and radiographic improvement during appropriate antibiotic therapy. Ongoing sepsis, recurrent positive blood cultures, and persistence or enlargement of splenic defects CT or MRI suggest splenic abscess, which responds poorly to antibiotic therapy alone. Definitive treatment is splenectomy with appropriate antibiotics. Percutaneous drainage or aspiration of splenic abscess is an alternative to splenectomy for the patient who is a poor surgical candidate. Splenectomy should be performed before valve-replacement surgery because of the risk of infection of the valve prosthesis as a result of the bacteremia from abscess.


Related Discussions:- Splenic abscess

Explain the nucleic acid is the transforming agent or not, Fredrick Griffit...

Fredrick Griffith published a series of experiments that collectively were dubbed "The Transforming Principle" in 1928. Which of the following prevented him from being able to decl

What are the five human digestive secretions, Q. What are the five human di...

Q. What are the five human digestive secretions? Which of them is the only pne that does not contain digestive enzymes? The human digestive secretions are: bile, saliva, gastri

Describe prematurity in coronaw artery disease, Describe Prematurity in cor...

Describe Prematurity in coronaw artery disease ? CAD in Indians tends to be more aggressive and manifests at a younger age. Generally CAD occurring before the age of 55 years i

Complications during angina pectoris, Q. Complications during angina pector...

Q. Complications during angina pectoris? It is a symptom giving a warning of impending myocardial infarction, sudden cardiac death or even ischemic necrosis of the brain leadin

Define assessment of manganese status, Define Assessment of Manganese Statu...

Define Assessment of Manganese Status? The body Mn status has not been yet established by laboratory tests. Though the normal range of serum Mn concentration is found out to b

Limiting factors of green plants, What are likely to be the limiting factor...

What are likely to be the limiting factors in a population of (a) green plants, (b) birds?  (a) In green plants the limiting factors are likely to be light, water, minerals, te

Define feeding and nutritional management of dysphilgia, Define Feeding and...

Define Feeding and Nutritional Management of Dysphilgia? A multidisciplinary approach is essential for successful management of dysphilgia. Patient, nurse, physician, die titi

Give an overview about operons, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 Various protein-codi

What is enzyme kinetics, What is enzyme kinetics The study of the rate ...

What is enzyme kinetics The study of the rate at which an enzyme works is called enzyme kinetics.

Explain the factors affecting the process of deep fat frying, Factors affec...

Factors affecting the process of deep fat frying. The common factors influencing the process of deep frying include: 1.  Heat- Frying temperatures ranging from 150 -190°C

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd