Splenic abscess, Biology

Assignment Help:

Splenic infarction is a common complication of left-sided IE (40 per cent of cases). Only 5 per cent of patients with splenic infarction will develop splenic abscess. This infection develops via 1 of 2 mechanisms Bacteremic seeding of a bland infarction, created via splenic artery occlusion by embolized vegetations, or direct seeding of the spleen by an infected embolus also originating from an infected valvular vegetation. Viridans streptococci and S aureus each account for 40 per cent of cases in which splenic abscess cultures are positive, whereas the enterococci account for 15 per cent of cases. Aerobic Gram-negative bacilli and fungi are isolated in, 5 per cent of cases. Clinical splenomegaly, present in up to 30 per cent of cases of IE, is not a reliable sign of splenic infarction or abscess. Splenic infarction delineated by imaging techniques is often asymptomatic Back, left-flank, or left-upper-quadrant pain or abdominal tenderness, when present, may be associated with either splenic infarction or abscess. Splenic rupture with hemorrhage is a rare complication of infarction. Persistent or recurrent bacteremia, persistent fever, or other signs of sepsis are suggestive of splenic abscess, Abdominal CT or MRI appear to be the best tests for diagnosis of splenic abscess, with sensitivities and specificities of 90 per cent to 95 per cent. On ultrasonography, a sonolucent lesion suggests abscess. Infarcts are generally associated with clinical and radiographic improvement during appropriate antibiotic therapy. Ongoing sepsis, recurrent positive blood cultures, and persistence or enlargement of splenic defects CT or MRI suggest splenic abscess, which responds poorly to antibiotic therapy alone. Definitive treatment is splenectomy with appropriate antibiotics. Percutaneous drainage or aspiration of splenic abscess is an alternative to splenectomy for the patient who is a poor surgical candidate. Splenectomy should be performed before valve-replacement surgery because of the risk of infection of the valve prosthesis as a result of the bacteremia from abscess.


Related Discussions:- Splenic abscess

Fertilization - pre-embryonic development, Fertilization - Pre-Embryonic De...

Fertilization - Pre-Embryonic Development Ovulation generally takes place between 9th to 14th day after the end of last menstrual period. Fertilization of oocyte initiates dev

Biological adaptation, Biological Adaptation These adaptations depend ...

Biological Adaptation These adaptations depend on the geology and basic fertility of the region and some of the mechanisms that are especially well developed in tropical rain

What is the parasite that causes giardiasis, Q. What is the parasite that c...

Q. What is the parasite that causes giardiasis? How is it transmitted and what are the typical manifestations of the disease? The Giardiasis is a protozoal infection caused by

Calamity & emergency management - nutritional needs of human, Define Calami...

Define Calamity and Emergency Management - nutritional needs of humans? During past many years, we have seen, as well as, realized -that natural calamities strikes countries, b

Explain the biography of pedanius dioscorides, Explain the Biography of Ped...

Explain the Biography of Pedanius Dioscorides? Pedanius Dioscorides, a Cicilian Greek, who lived in the first century A.D. was the most important botanist after Theophrastus. H

Define about the simple proteins, Define about the Simple proteins? Sim...

Define about the Simple proteins? Simple proteins are those which contain only amino acids or their derivatives and no prosthetic group. They yield only amino acids or their de

Explain surviving implants, What is Surviving Implants It is a term des...

What is Surviving Implants It is a term described by Albrektsson that applies to implants that are still in function but have not been tested against success criteria. Such as

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd