Splenic abscess, Biology

Assignment Help:

Splenic infarction is a common complication of left-sided IE (40 per cent of cases). Only 5 per cent of patients with splenic infarction will develop splenic abscess. This infection develops via 1 of 2 mechanisms Bacteremic seeding of a bland infarction, created via splenic artery occlusion by embolized vegetations, or direct seeding of the spleen by an infected embolus also originating from an infected valvular vegetation. Viridans streptococci and S aureus each account for 40 per cent of cases in which splenic abscess cultures are positive, whereas the enterococci account for 15 per cent of cases. Aerobic Gram-negative bacilli and fungi are isolated in, 5 per cent of cases. Clinical splenomegaly, present in up to 30 per cent of cases of IE, is not a reliable sign of splenic infarction or abscess. Splenic infarction delineated by imaging techniques is often asymptomatic Back, left-flank, or left-upper-quadrant pain or abdominal tenderness, when present, may be associated with either splenic infarction or abscess. Splenic rupture with hemorrhage is a rare complication of infarction. Persistent or recurrent bacteremia, persistent fever, or other signs of sepsis are suggestive of splenic abscess, Abdominal CT or MRI appear to be the best tests for diagnosis of splenic abscess, with sensitivities and specificities of 90 per cent to 95 per cent. On ultrasonography, a sonolucent lesion suggests abscess. Infarcts are generally associated with clinical and radiographic improvement during appropriate antibiotic therapy. Ongoing sepsis, recurrent positive blood cultures, and persistence or enlargement of splenic defects CT or MRI suggest splenic abscess, which responds poorly to antibiotic therapy alone. Definitive treatment is splenectomy with appropriate antibiotics. Percutaneous drainage or aspiration of splenic abscess is an alternative to splenectomy for the patient who is a poor surgical candidate. Splenectomy should be performed before valve-replacement surgery because of the risk of infection of the valve prosthesis as a result of the bacteremia from abscess.


Related Discussions:- Splenic abscess

Define the antigen-presenting cells of the immune system, Q. What are the a...

Q. What are the antigen-presenting cells of the immune system? The antigen-presenting cells of the immune system also known as APC cells are cells that do digestion and phagocy

What is working of mouth in human body, What is Working of Mouth in human b...

What is Working of Mouth in human body? Food enters the digestive system through the mouth, where it is processed by the teeth and mixed with saliva, prior to being swallowed.

Describe the advantages of sulphur, Describe the advantages of sulphur ...

Describe the advantages of sulphur Sulphur also increases the oil content of crops such as flax and soyabeans. Disulphide linkages ( -S-S-) have recently been associated with

Protection against insect bites, Protection Against Insect Bites To mi...

Protection Against Insect Bites To minimize insect bites, travellers should wear light-colored, long-sleeved shirts, pants and socks. The most effective topical insect repelle

Plants of dry environment open their stomata only at night, Why do few plan...

Why do few plants adapted to a dry environment open their stomata only at night? Throughout the day in dry habitats the guard cells become the stomata close and flaccid; concur

Epilimnion - summer stratification, Epilimnion - Summer Stratification ...

Epilimnion - Summer Stratification This forms the upper layer of the lake and consists of freely- circulating warm water which is well lighted though poor in nutrients. Most o

Contig, Contig:  Number of uses, all nouns. The term comes from the shorten...

Contig:  Number of uses, all nouns. The term comes from the shortening of the word 'contiguous'. A 'contig' might refer to the map showing placement of a set of clones which comple

A plant growing on a mountainside, What two abiotic factors might affect (a...

What two abiotic factors might affect (a) an animal living at the bottom of the sea, (b) a plant growing on a mountainside?   (a) The abiotic factors which might

Explain how movement is controlled in protozoans., Movement is even control...

Movement is even controlled by organelles, cilia and flagella. These and the pseudopodia in the amoebas give these small creatures movement, something we associate with animals. Es

Complications of exchange transfusion, Complications of Exchange Transfusio...

Complications of Exchange Transfusion i) Infection of umbilical vessels and systemic injection related to blood transfusion like malaria, CMV, AIDS and hepatitis B. ii) O

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd