Splenic abscess, Biology

Assignment Help:

Splenic infarction is a common complication of left-sided IE (40 per cent of cases). Only 5 per cent of patients with splenic infarction will develop splenic abscess. This infection develops via 1 of 2 mechanisms Bacteremic seeding of a bland infarction, created via splenic artery occlusion by embolized vegetations, or direct seeding of the spleen by an infected embolus also originating from an infected valvular vegetation. Viridans streptococci and S aureus each account for 40 per cent of cases in which splenic abscess cultures are positive, whereas the enterococci account for 15 per cent of cases. Aerobic Gram-negative bacilli and fungi are isolated in, 5 per cent of cases. Clinical splenomegaly, present in up to 30 per cent of cases of IE, is not a reliable sign of splenic infarction or abscess. Splenic infarction delineated by imaging techniques is often asymptomatic Back, left-flank, or left-upper-quadrant pain or abdominal tenderness, when present, may be associated with either splenic infarction or abscess. Splenic rupture with hemorrhage is a rare complication of infarction. Persistent or recurrent bacteremia, persistent fever, or other signs of sepsis are suggestive of splenic abscess, Abdominal CT or MRI appear to be the best tests for diagnosis of splenic abscess, with sensitivities and specificities of 90 per cent to 95 per cent. On ultrasonography, a sonolucent lesion suggests abscess. Infarcts are generally associated with clinical and radiographic improvement during appropriate antibiotic therapy. Ongoing sepsis, recurrent positive blood cultures, and persistence or enlargement of splenic defects CT or MRI suggest splenic abscess, which responds poorly to antibiotic therapy alone. Definitive treatment is splenectomy with appropriate antibiotics. Percutaneous drainage or aspiration of splenic abscess is an alternative to splenectomy for the patient who is a poor surgical candidate. Splenectomy should be performed before valve-replacement surgery because of the risk of infection of the valve prosthesis as a result of the bacteremia from abscess.


Related Discussions:- Splenic abscess

Define growth hormone releasing hormone receptors, Define GHRH Receptors (G...

Define GHRH Receptors (Growth Hormone Releasing Hormone Receptors)? A. GHRH Receptors are only located in the plasma membranes of cells in the hypothalamus. B. GHRH Receptor

Explain the term- loss-of-function mutation, Where would a predicted silent...

Where would a predicted silent mutation have to be situated to actually result in a loss-of-function mutation (and potentially lead to the onset of disease)? A. Intron-exon jun

Define vaccine immunogenicity, Immunogenicity Based on immunogenicity s...

Immunogenicity Based on immunogenicity studies and experience with other vaccines, the new meningococcal conjugate vaccine (Menactra) should be highly effective in preventing m

Define factors affecting energy expenditure and requirement, Define Factors...

Define Factors Affecting Energy Expenditure and Requirement? As mentioned earlier, the energy needs vary widely among individuals in a group. Why? A number of factors cause the

Describe consciousness as the waking state, Q. Describe Consciousness as th...

Q. Describe Consciousness as the waking state? Consciousness as the waking state: consciousness is also referred to as the waking state as opposed for example to sleep. All

Morphogenesis and totipotency, Morphogenesis and Totipotency A chlamy...

Morphogenesis and Totipotency A chlamydomonas mother cell gives rise to two daughter cells by a simple division. But a leaf cell cannot give rise to a new plant except in cas

Define nutritional needs during recovery, Define nutritional needs During R...

Define nutritional needs During Recovery? Here, let us discuss what should be the nutritional goals based on the physiological aspects involved. Goals: The main emphasis mus

How different are the ureotelic and the uricotelic excretion, Comparing tox...

Comparing toxicity and the requirement for dilution in water how different are the ureotelic and the uricotelic excretions? What are some examples of animals that present these res

Explain the recommended dietary allowances (rda), Explain the Recommended D...

Explain the Recommended Dietary Allowances (RDA)? The recommended dietary allowances are estimates of nutrients to be consumed daily to ensure the requirements of all individua

What is pulsus bisferians explain in details, What is Pulsus Bisferians exp...

What is Pulsus Bisferians explain in details? Pulsus Bisferians: A condition in which double notch is found near or at the height of pulse wave. Typically it is associated with

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd