Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
All the cells present in the body contain genes and an approach targeted to modulate the expression of genes is known as gene therapy. This novel approach has emerged by the end of 20th century and comes up with a promise of treating a large number of genetic disorders by ultimately modifying the gene expression (Jin et al, 2008). The two forms of gene therapy are somatic and germ line.
Somatic gene therapy: During this therapeutic approach, the genetic diseases are treated by inserting recombinant genes into non-reproductive or somatic cells. This kind of approach is limited to the patient and does not get transmitted to the future generations of. A normal copy of the malfunctioning gene is inserted into the mutant cells due to which an improvement in the disease phenotype is observed (Dorin, 1996). In the recent past, this technique has been found to be successful in case of familial hypercholesterolaemia and adenosine deaminase deficiency. For treating these disorders hepatocytes and T cells have been used for gene transfer respectively (Dorin, 1996). It has also shown significant success in case of cystic fibrosis and cancer. Various vehicles, like viral and non viral vectors help in the introduction of the genetic material into the mutated cells (Elias and Annas, N.D). This therapeutic approach is categorized into three sections:
However this approach produces short term results as the tissues die and get replaced with other cells.
Q. Why are lysosomes known as "the cleaners" of the cell waste? Lysosomes carry out heterophagic and autophagic digestion autophagic digestion by digesting residual substances
What is the difference between self pollination and cross pollination? Which of these two modes of pollination contributes more to the plant diversity? Self pollination happens
MOD E OF HORMONE ACTION THROUGH EXTRACELLULAR RECEPTORS - The molecules of amino acid derivatives, peptides or polypeptide (protein) hormones bind to specific receptor molecul
What is an example of a parasite relationship? An example would be a flea and a dog. The flea drinks the dog's blood, but does nothing helpful for the dog.
DISORDERS OF UPPER RESPIRATORY TRACT: Common Cold: It is most frequent and most common infection in infants and children. Common cold corresponds to acute nasopharyn
Eucaryotic cell structure All eucaryotic cells have a cytoskeleton made up of a network of protein filaments (Figure shown below). This network gives the cell its shape, capac
Explain about the Microcolony DEFT? It allows determination of viable cells. Food homogenate is filtered through a DEFT membrane and then placed on the surface of appropriate c
As a result of DNA replication two DNA molecules come into existence. Why is it not correct to assert that two "new" DNA molecules are created? What is the name given to the proces
LIST SOME DISADVANTAGES OF ROTOZOA
Define Titrimetric Method - 2, 6 Dichlorophenol Indophenol Method? The titrimetric method is a redox titration method which depends on the reduction of the blue dye 2,6 dichlor
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd