Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
All the cells present in the body contain genes and an approach targeted to modulate the expression of genes is known as gene therapy. This novel approach has emerged by the end of 20th century and comes up with a promise of treating a large number of genetic disorders by ultimately modifying the gene expression (Jin et al, 2008). The two forms of gene therapy are somatic and germ line.
Somatic gene therapy: During this therapeutic approach, the genetic diseases are treated by inserting recombinant genes into non-reproductive or somatic cells. This kind of approach is limited to the patient and does not get transmitted to the future generations of. A normal copy of the malfunctioning gene is inserted into the mutant cells due to which an improvement in the disease phenotype is observed (Dorin, 1996). In the recent past, this technique has been found to be successful in case of familial hypercholesterolaemia and adenosine deaminase deficiency. For treating these disorders hepatocytes and T cells have been used for gene transfer respectively (Dorin, 1996). It has also shown significant success in case of cystic fibrosis and cancer. Various vehicles, like viral and non viral vectors help in the introduction of the genetic material into the mutated cells (Elias and Annas, N.D). This therapeutic approach is categorized into three sections:
However this approach produces short term results as the tissues die and get replaced with other cells.
Hom o sapiens sapiens (MODER N MAN) - Developed from Cro-Magnon about 10,000 years ago after last glacial period in the regions of Caspian and Mediterranean seas.
Q. What is the disease caused by vitamin D deficiency? Which tissue does it affect? The lack of vitamin D causes the disease known as rickets (rachitis), characterized by bone
protozoa is divided into how many sub phykum?
Explain Doctrine of Signatures? Handed down from the ancients, and elaborated on by the herbalists, was the 'Doctrine of Signatures', which was based on features that resembled
binomial nomenclature is not applicable to
Q. What are the intermediate and the definitive hosts of the plasmodium? In the life-cycle of the plasmodium humans are the intermediate hosts (where asexual reproduction takes
Extra-ocular muscles There are, as you know, six extra-ocular muscles. Out of these, four are recti(straight) and two are oblique. They control the position and movement of th
Explain the Manifestations of Iron Deficiency Anaemia? • Paleness of conjunctiva • Paleness of tongue • Paleness of mucosa of soft palate • Low haemoglobin • Swelling of
Cap site Two usages are given below: 1] In eukaryotes, the cap site is position in the gene at which transcription begins, and really should be called the "transcription initia
Restricted Food Items Foods to be avoided by diabetic patient are carbohydrate and fatty food. Carbohydrates are classified into sugars and starches. As you have studied in und
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd