Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Phylum porifera, harmful and beneficial usesa of phylum porifera

harmful and beneficial usesa of phylum porifera

Explain electrocardiography, Explain electrocardiography? What is mean...

Explain electrocardiography? What is meant by P-Q interval and S -T interval in electrocardiography? Mention two medical applications of this method.

In how many parts minerals are divided, Classification of Minerals Mine...

Classification of Minerals Minerals can be separated into two main categories, namely, main elements (calcium, potassium, phosphorous, chlorine, sodium, magnesium) and trace el

Process of regeneration in planarians, Process of Regeneration in Planarian...

Process of Regeneration in Planarians Regeneration in planarians has been broadly studied and considerable information regarding this phenomenon is now available. Let us see w

Hormones controlling other functions, Hormones Controlling Other Functions ...

Hormones Controlling Other Functions Crustacean's exhibit pronounced capacity for physiological color changes. It is known that the color changing mechanisms in Crustacea are

State the article - one hundred tests, Regarding the article "One Hundred T...

Regarding the article "One Hundred Tests" which of the following is a false statement? A. Genetic tests like the one developed by Counsyl can examine the multilevel genetic net

Define the fehling's soxhlet method (lane-eynon method), Define the Fehling...

Define the Fehling's Soxhlet method (Lane-Eynon method)? This is a titrimetric method that is commonly used in food laboratories to estimate percentage of reducing sugars and t

Cooking of vitamin c-containing foods, Q. Why isn't the cooking of vitamin ...

Q. Why isn't the cooking of vitamin C-containing foods appropriate for vitamin C supply? To obtain vitamin C, for instance, from an orange dessert, the vitamin- containing food

Explain the sampling and analysis of microbial load, Explain the Sampling a...

Explain the Sampling and Analysis of Microbial Load? A food or equipment can be free of visible dirt and still be carrying microorganisms or chemicals that can cause food borne

How can amine groups be classified, Q. How can amine groups be classified? ...

Q. How can amine groups be classified? Amines can be classified into primary amines, those to which one -R (variable radical) is attached to a -NH 2 , secondary amines, those w

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd