Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What are the constituent elements of the blood, What are the constituent el...

What are the constituent elements of the blood? The blood is made of a liquid and a cellular part. The fluid part is known as plasma and in it there are several substances, suc

Characteristic of ecotone, Characteristic of Ecotone A general charact...

Characteristic of Ecotone A general characteristic of ecotone is that it has sufficiently greater number of species and the diversity of most of the species at times is higher

Air pollution- introduction, Air pollution is complex in origin and varied ...

Air pollution is complex in origin and varied in effect. It is very crucial from the point of human health. Every human being inhales about 15-22 kg of air daily and air is pollute

Guanotelism - excretion, Guanotelism - Excretion Normal ...

Guanotelism - Excretion Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain the pre pregnancy height and foetal outcome, Explain the Pre Pregna...

Explain the Pre Pregnancy Height and Foetal Outcome? Maternal height prior to conception, determined by heredity, socio-economic environment and maternal nutritional status, is

Rules of nomenclature classification, Q. Rules of Nomenclature classificati...

Q. Rules of Nomenclature classification? The Rules of Nomenclature prescribed the categories into which plants should be classified. These categories constitute the units of cl

Monounsatuated fats required for dyslipidemia, Q. Monounsatuated fats requi...

Q. Monounsatuated fats required for dyslipidemia? Monounsatuated fats (MUFA): These are liquid at room temperature, the highest food source being olive oil, canola oil, rapesee

Compute the diffusion coefficient of a protein, Calculate the diffusion coe...

Calculate the diffusion coefficient of a protein bovine serum albumin at 23 degree Celsius?

Reproductive organs, Reproductive Organs In several metazoans, gonads ...

Reproductive Organs In several metazoans, gonads are well-defined. Testes and ovaries take up dissimilar shapes and anatomical dispositions. In cases of certain hermaphrodites

Determine the foos sources of cyanocobalamin, Determine the Foos Sources of...

Determine the Foos Sources of cyanocobalamin? Vitamin B I2 is unique among vitamins in the sense that it is mostly found in foods of animal origin but is not generally present

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd