Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What is ventricular septal defect, What is Ventricular Septal Defect (VSD) ...

What is Ventricular Septal Defect (VSD) ? VSD accounts for 15-20 per cent of all CHDs. The ventricular septum may be divided into a small membranous portion and a large muscula

Chemical reaction to unite amino acids liberate, Q. Does the chemical react...

Q. Does the chemical reaction to unite amino acids liberate or incorporate atoms? What are the chemical entities liberated or incorporated in this reaction? The union of amin

Excretion., organisms and their excretory organelles

organisms and their excretory organelles

True about microbial metabolism, which of the following is most likely to b...

which of the following is most likely to be true of microbial metabolism? 1)Acetyl-CoA is converted directly into 2 ATP 2)The energy from 2 ATP is necessary to drive the electron t

Effects of solid waste pollution, The improper handling and transfer of the...

The improper handling and transfer of the solid wastes results in various health and environmental hazards, such as: 1.      Spoilage of landscape: Municipal wastes heap up o

Explain the bone implant interface, Q. Explain the Bone Implant Interface? ...

Q. Explain the Bone Implant Interface? Three phases have been described in the development of bone implant interface. 1. Stabilization phase Subendosteal and subperiost

Monosaccharides and disaccharides, Monosaccharides are frequently known as...

Monosaccharides are frequently known as single or simple sugars and are the easiest of all carbohydrates. That is the building blocks of all higher carbohydrates. The Monosacchari

Quantitative real-time pcr, 1. You are given a pair of primers that has bee...

1. You are given a pair of primers that has been shown amplify a 125 bp DNA of interest specifically by a end point PCR- as there was only one PCR product with a size of 125 bp det

What is sports nutrition, What is Sports Nutrition? Sports nutrition i...

What is Sports Nutrition? Sports nutrition is a discipline which applies principles derived not only from nutritional but also biochemical and physiological scientific knowled

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd