Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Define drug effects on food intake - gastro intestinal tract, Define Drug E...

Define Drug Effects on Food Intake - gastro intestinal tract? Affect the gastro intestinal tract: Gastrointestinal irritation and ulceration are serious problems with many drug

Respiration, what is the respiration interdisiplinary field,legal concerns,...

what is the respiration interdisiplinary field,legal concerns,backgroun and ad vantages and diadvantages

Acute renal failure and its etiology, Acute Renal Failure You know tha...

Acute Renal Failure You know that acute renal failure refers to the sudden deterioration in kidney function, characterised by reduced urine excretion to less than 10 ml/kg  bo

Can you explain toxic alkaloids, Q. Can you explain Toxic alkaloids? Al...

Q. Can you explain Toxic alkaloids? Alkaloids are the nitrogen heterocycles which occur mainly m plants as their salts of common carboxylic aciak such as citric, lac

Explain about the vitamin d, Explain about the Vitamin D? Vitamin D is ...

Explain about the Vitamin D? Vitamin D is a generic term and indicates a molecule of the general structure with  rings (A, B, C, D), as you may have noticed in Figure B. The ri

Regulation of heart, Regulation of Heart The number of electrical imp...

Regulation of Heart The number of electrical impulses initiated by the SA node is primarily the result of its innervation by fibers from both sympathetic and parasympath

Why deficiency of folate take place, Why Deficiency of Folate take place? ...

Why Deficiency of Folate take place? If there is inadequate dietary folate, the activity of both the DNA and the methylation cycles, described above, will be reduced. A decrea

Define the diseses shigellosis, Define the diseses Shigellosis Shigello...

Define the diseses Shigellosis Shigellosis or bacterial dysentery is caused by facultative anaerobic, gram-negative, non-spore forming, rod-shaped  Shigella in the family enter

What do you understand by metanephridia, What do you understand by Metaneph...

What do you understand by Metanephridia? An excretory-osmoregulatory organ comprising a ciliated funnel, nephrostome, connected to tubules that lead to the external nephridiopo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd