Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

How do contraceptive pills generally work, Q. How do contraceptive pills ge...

Q. How do contraceptive pills generally work? Contraceptive pills generally contain the hormones progesterone and estrogen. If taken daily from the 4th day after menses the abn

Explain beginning and the end of the third interphase period, Q. What are t...

Q. What are the events that mark the beginning and the end of the third interphase period? What happens in the cell in this period? The third interphase period is the G2, It be

In what form nitrogenous wastes excreted in birds, In what forms are nitrog...

In what forms are nitrogenous wastes excreted in birds, humans and aquatic turtles respectively ? Why so, describe?

How different is the gametogenesis in men and in women, Q. Concerning event...

Q. Concerning events during the periods of life how different is the gametogenesis in men and in women? The formation of spermatogonia in men takes place during the embryonic p

Explain about the demand curve or schedule in short, Explain about the Dema...

Explain about the Demand curve or schedule in short. The demand curve or demand schedule shows the total quantity purchased through all buyers, within aggregate, into the marke

What is mean by stability study, Stability studies are req. for the product...

Stability studies are req. for the product stable at their desire time as per specification , which give the expiry date and quality as per the manner.

Sql''s fifth concept - null, SQL's Fifth Concept - NULL Unfortunately...

SQL's Fifth Concept - NULL Unfortunately, SQL embraces a fifth concept, called NULL, an apparently simple little thing but one that has pervasive effects on our usual underst

Cloning protocol, Sally Subcloner wants to clone a fragment into pUC19 (Map...

Sally Subcloner wants to clone a fragment into pUC19 (Map above - From New England Biolabs). Her fragment was a protein coding gene of 2.7 kb, and had Xho I sites on either end (a

List four possible after-effects of solvent abuse, List four possible after...

List four possible after-effects of solvent abuse (glue-sniffing). Possible after-effects of solvent abuse are headache, nausea, vomiting, convulsions, runny nose, a rash round

Heat production and respiratory quotient for foodstuff types, Heat producti...

Heat production and respiratory quotient for foodstuff types The heat produced during the metabolic activities of the body helps in maintaining the body temperature. Generally

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd