Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Phlum arthropoda, how to write a project on phylum arthropoda

how to write a project on phylum arthropoda

What is hemorrhage, What is Hemorrhage Mild to moderate capillary ooze...

What is Hemorrhage Mild to moderate capillary ooze can readily be controlled by pressure packing. A more severe venous or, in rarer instances, an arterial bleed may require cl

Illustrate the functional properties of proteins, Functional properties of ...

Functional properties of protiens Immunoproteins such as C-reactive protein, Opsonin Immunoglobulins, Contractile respiratory, structural, enzymatic,

What are the major factors of colloidal dispersion, What are the major fact...

What are the major factors of colloidal dispersion The adsorption of ions by colloidal particles is a major factor in stabilizing a colloidal dispersion, since the colloidal pa

Why are euglenas involved in polemics, Why are euglenas involved in polemic...

Why are euglenas involved in polemics related to their taxonomic classification? Euglenas are included in taxonomic polemics because they tend to be classified sometimes as pro

Tolerance range - ecosystem, Tolerance Range - Ecosystem Organisms are...

Tolerance Range - Ecosystem Organisms are able to survive only within certain maximum and minimum limits with respect to each environmental factor such as water, light and tem

Respiration, what chemical is normally used to test for the presence of car...

what chemical is normally used to test for the presence of carbon dioxide

Clinical manifestation of emphysema, Clinical Manifestation   Early on...

Clinical Manifestation   Early onset of dyspnea on exertion (DOE) which progresses to continuous dyspnea. Rhonchi, crackles , accessory muscle breathing, Increased rate of br

Ideal eia and measures and benefits of eia, An ideal EIA system would: ...

An ideal EIA system would: (i)     Apply to all projects that are expected to have significant environmental effects and address all impacts that are expected to occur due to t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd