Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What is the function of vitamin e, What is the function of vitamin E? In wh...

What is the function of vitamin E? In which foods can it be found? Vitamin E, or tocopherol, is a fat-soluble vitamin that participates as coenzyme in the respiratory chain, t

Management of diabetes, By now you know that diabetes cannot be cured but c...

By now you know that diabetes cannot be cured but can be treated so that an individual leads a normal life. Patients who maintain their blood glucose levels within the normal range

Define the fehling's soxhlet method (lane-eynon method), Define the Fehling...

Define the Fehling's Soxhlet method (Lane-Eynon method)? This is a titrimetric method that is commonly used in food laboratories to estimate percentage of reducing sugars and t

What do carbon chains common with a skeletal system, What do carbon chains ...

What do carbon chains have in common with a skeletal system?

Explain dextran, Dextran Dextran is a high molecular  weight polysaccha...

Dextran Dextran is a high molecular  weight polysaccharide having  α1→ 6,  α1→ 3 linked glucans. It is produced by the bacterial fermentation of sucrose by  Leuconostoc dextran

Define limitations of agar syringe or agar sausage method, Define Limitatio...

Define Limitations of Agar Syringe or Agar Sausage Method? (i) It is applicable to surfaces with low contaminants. (ii) Problem of spreading colonies may occur. (iii) Col

Third week - embryonic development, Third Week - Embryonic Development ...

Third Week - Embryonic Development Throughout the third week of development the ICM separates from the uophoblast and forms the flattened embryonic disc, which at first consi

When aerobic cells carry out fermentation, Under which conditions do aerobi...

Under which conditions do aerobic cells carry out fermentation? Some cells that as a rule get energy from aerobic cellular respiration can carry out fermentation when oxygen is

What is barr body genes, Q. What is Barr body Genes? Located inside nuc...

Q. What is Barr body Genes? Located inside nuclear envelope, it's a densely staining object which is an inactivated X chromosome in female mammalian cells. Most Barr body genes

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd