Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Different types of ecosystem, An ecosystem is a self sufficient interacting...

An ecosystem is a self sufficient interacting system in the biosphere. Eg. forest, desert, pond etc. almost, all the ecosystem have more or less similar fundamental plan for their

Explain the term trans fatty acids, Explain the term Trans fatty acids? ...

Explain the term Trans fatty acids? Plant derived fats and oils contain cis-fatty acids. You may recall reading about the cis and trans isomers in the Nutritional Biochemistry

Electron acceptor, Electron acceptor is a molecule which forms the part of...

Electron acceptor is a molecule which forms the part of the electron transport system which transfers electrons ejected by chlorophyll during the process of photosynthesis. Part o

Reflex action, REFLE X ACTION - Marshel Hall discovered reflex ac...

REFLE X ACTION - Marshel Hall discovered reflex action. Best & Taylor defined it. Reflex action is functional unit of CNS. It is sudden, immediate involuntary acti

Explain about gastric ulcers, Q. Explain about Gastric ulcers? Gastric ...

Q. Explain about Gastric ulcers? Gastric ulcers occur in the lesser curvature of the antrum of stomach. A gastric ulcer appears to be caused by reflux of bile and factors that

Disorders of motor neurons and the spinal cord, Disorders of motor neurons ...

Disorders of motor neurons and the spinal cord A number of movement disorders are produced by damage either to the spinal cord or to cortical projections to the spinal cord. Th

What is the climax stage of an ecological succession, Q. What is the climax...

Q. What is the climax stage of an ecological succession? The climax stage is the stage of an ecological succession in which the community of an ecosystem turn into stable and d

The kidney.., where is the inlet and outlet of the diaylsis machine

where is the inlet and outlet of the diaylsis machine

Explain the compound water, Explain the compound water? Water :  Wate...

Explain the compound water? Water :  Water is the most important compound in living cells, making up most of the bulk of living organisms. Our own bodies contain 40% - 60% wa

Guidelines for diagnosis and treatment planning, Guidelines for diagnosis a...

Guidelines for diagnosis and treatment planning The diagnosis and planning the case is by far the most important step in the entire sequence of the treatment and due considerat

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd