Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Ethological isolation, Members belonging to different species refrain from ...

Members belonging to different species refrain from mating because of the behavioural differences between them. Such behavioural differences usually centre around specific courtshi

Determine the list of sensory organs, Determine the list of Sensory Organs ...

Determine the list of Sensory Organs There are four special sensory organs in our body. They are: 1) Eyes 2) Ears 3) Nose and 4) Skin

Effects of solid waste pollution, The improper handling and transfer of the...

The improper handling and transfer of the solid wastes results in various health and environmental hazards, such as: 1.      Spoilage of landscape: Municipal wastes heap up o

Illustrates the effect of wall movement on earth pressure, Illustrates abou...

Illustrates about the effect of wall movement on earth pressure? Effect of wall movement on earth pressure About fifty years ago Terzaghi conducted a series of tests on larg

Phylum Echinodermata, define and explain Water vascular system with podia a...

define and explain Water vascular system with podia and tube-feet madreporite mostly present

Describe about aorto pulmonary window, Describe about Aorto Pulmonary Windo...

Describe about Aorto Pulmonary Window ? This uncommon malformation consists of communication usually non-restrictive between the adjacent walls of the ascending aorta and pulmo

Lymph, LYMPH - Lymph is a mobile connective tissue comprising lymph pla...

LYMPH - Lymph is a mobile connective tissue comprising lymph plasma (fluid) and lymphcorpuscles (cells).   COMPOSITIO N - (i )      Lymph Plasma - It is simil

Explain diabetes mellitus, Diabetes mellitm This anabolic hormone exert...

Diabetes mellitm This anabolic hormone exerts its action on key glycolytic  enzymes  thus  leading  to the conversion of glucose  to  pyruvate as explained under the regulation

Cell surface junctions, CELL SURFACE JUNCTIONS (1 )      Desmosomes (...

CELL SURFACE JUNCTIONS (1 )      Desmosomes (Maculae adherence) - Thickened circular areas on P.M. of adjacent cells with radiating fibrils in cytoplasm. These fibrils calle

Protozoa, the function of contractil vacuole

the function of contractil vacuole

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd