Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Protozoa, what is the classification of protozoa

what is the classification of protozoa

Explain treatment of latent tb infection, Treatment of latent tb infection ...

Treatment of latent tb infection The risk of developing clinical tuberculosis is greatest in patients with latent TB who are also infected with HIV or are receiving immunosuppr

Describe the basic types of leukocytes, Q. What are the kinds of leukocytes...

Q. What are the kinds of leukocytes and how are they classified into granulocytes and agranulocytes? The kinds of lymphocytes are leukocytes, neutrophils, monocytes, basophils

What is bone modeling, Bone Modeling It is a surface-specific activity ...

Bone Modeling It is a surface-specific activity (apposition or resorption) that produces a net change in the size and/or shape of a bone after initial bone formation in the emb

Explain complex or undefined media, Explain Complex or Undefined Media? ...

Explain Complex or Undefined Media? Here, the exact composition of the medium is not known. It contains some complex components of plant and animal extracts whose exact chemica

What do you mean by biodigester, Q. What do you mean by biodigester? A ...

Q. What do you mean by biodigester? A biodigester is equipment that produces hydrogen sulfide, carbon dioxide and fuel gases (biogases) like methane from organic material under

Water, Water Water usually forms about 50% to90% part of living protopl...

Water Water usually forms about 50% to90% part of living protoplasm. Life upon earth originated in the ocean and the conditions of that aqueous primeval environment have been r

If jean-baptiste de lamarck was correct so result will be, If jean-Baptiste...

If jean-Baptiste de Lamarck was correct, than a. Natural selection would lead to the spread of favourable traits within a population b. Finches that stretched their beaks to access

Ststems of human body, what is reproductive system? what is urinary System?...

what is reproductive system? what is urinary System? What is Nervous system

List what organelle is responsible, List what organelle is responsible for ...

List what organelle is responsible for each of these cellular functions. -production of energy (ATP) for the cell -synthesizing proteins -cellular digestion.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd