Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What are the main human diseases caused by virus, What are the main human d...

What are the main human diseases caused by virus? Between diseases caused by virus are common cold, flu, mumps, variola (considered eradicated nowadays), rubella, AIDS, measles

Explain about the endocrine system, Why is the endocrine system considered ...

Why is the endocrine system considered one of the integrative systems of the body? What is the other physiological system that also has this function? The endocrine system is s

Explain the absorption, Explain the Absorption, Storage and Elimination of ...

Explain the Absorption, Storage and Elimination of thiamin? After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both acti

Determine the concept of neuropsychological test, Determine the concept of ...

Determine the concept of neuropsychological test A neuropsychological test therefore is defined as behavioural procedure that is particularly sensitive to the condition of the

Can you explain antibiotics, Q. Can you explain Antibiotics? The antibi...

Q. Can you explain Antibiotics? The antibiotics are the chemicals produced by microorganisms which are able to destroy or inhibit the growth of other microorganisms. The therap

Explain the properties of gum karaya, Explain the Properties gum karaya ...

Explain the Properties gum karaya Gum karaya is water-swellable rather than water-soluble and absorbs water very rapidly to form viscous colloidal dispersions at low concentra

Skeletal system - face, FAC E - It lies under the anterior part of ...

FAC E - It lies under the anterior part of cranium. It is composed of 14 bones. These includes 2 nasals, 2 maxillae, 2 palatine, 2 zygomatic, 2 lacrymals, 2 inferior

What is enzyme proteins, Enzyme  Proteins   that act  as  catalysts, speed...

Enzyme  Proteins   that act  as  catalysts, speeding the rate  at  which biochemical reactions proceed but not altering the direction or nature of the reactions.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd