Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What is vacuoles, What is Vacuoles A very conspicuous feature in most p...

What is Vacuoles A very conspicuous feature in most plant cells is the presence of one or more large vesicles called vacuoles which are separated from the rest of the cytoplasm

Deforestation - degradation of ecosystem, Deforestation - Degradation of Ec...

Deforestation - Degradation of Ecosystem The deforestation is a broad term. It means the removal/destruction of the forest cover or the vegetation of an area. It includes repe

State the active hyperemia, Which of the following is true for active hyper...

Which of the following is true for active hyperemia, a local control mechanism within the circulatory system? A. There will be a decrease in force developed by smooth muscles s

DNA damaged by alkylating agents, Q. DNA damaged by alkylating agents? ...

Q. DNA damaged by alkylating agents? 1. Some simple alkylating agents 2. Illustrations of products of alkylating agents 3.Many of these products can be repaired by excision rep

Nutrition, Why is holophytic nutrition a mode of autotrophic nutrition

Why is holophytic nutrition a mode of autotrophic nutrition

Centrioles, Centrioles Centrioles is also called cell centre . C...

Centrioles Centrioles is also called cell centre . Centrosome discovered by Benden . T. Boveri called it centrosome. Centrosome is present in all animal eukaryotic

What is catalyzes a substrate level phosphorylation, The enzyme in the TCA ...

The enzyme in the TCA cycle that catalyzes a substrate level phosphorylation is -citrate dehydrogenase -succinate thiokinase -isocitrate dehydrogenase

Anticoagulation in prosthetic valves, Anticoagulation in Prosthetic Valves ...

Anticoagulation in Prosthetic Valves The usual anticoagulants used are: (I) Warfarin sodium, and (2) Acitrorn (coumarin derivative). In patients who had thromboembolism

Clinical features - rheumatic fever, The American Heart Association (AHA) h...

The American Heart Association (AHA) has recommended the revised Jones Criteria as a guide for ARF diagnosis. The same have been approved by WHO study group for the diagnosis of in

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd