Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Effects of environmental disasters, Primary effects 1.      Nuclear con...

Primary effects 1.      Nuclear contamination 2.      Biological contamination 3.      Chemical contamination 4.      Destruction of infrastructure facilities. 5.

Arteries - circulation, Arteries - Circulation The arteries deliver bl...

Arteries - Circulation The arteries deliver blood from the heart. Figure shows the structure of arteries and the different layers of the vessel wall. The thick walls of these

Female gametophyte formed in angiosperms, Q. How is female gametophyte form...

Q. How is female gametophyte formed in angiosperms? Into the flower ovary there are megasporangia enclosed by a tegument having a small opening, the micropyle. Inside the megas

Difference between ulcerative colitis and crohns disease, What is the diffe...

What is the difference between ulcerative colitis and Crohn's disease? The differences between the two include: I) Anatomic distribution of the inflammatory process: Crohn'

Necrotic enteritis, N e c r otic enteritis It can be designated as ...

N e c r otic enteritis It can be designated as enterotoxaemia of chickens, turkeys and ducks caused by Clostridium perfringens. The toxin released by this spore-bearing a

Haemodynamic study of constrictive pericarditis, Q. Haemodynamic Study of c...

Q. Haemodynamic Study of constrictive pericarditis? Simultaneous right and left heart studies are useful. Due to exaggerated waves in atria, W-shaped atrial pressure tracing wi

Explain isozymes, ISOZYMES Sometimes an  enzyme present  in  the  same ...

ISOZYMES Sometimes an  enzyme present  in  the  same  organism is  found  to  have different molecular forms but  catalyzing the  same  reaction. These are called  isozymes. Th

Poisoning - pesticide toxicity, P o i s on i n g P e sticide ...

P o i s on i n g P e sticide toxicity Chemical pesticides were introduced as an important tool for pest control and have been used extensively in human health ope

Eyeball - choroid, CHOROI D - Thin, net like made up of connective ...

CHOROI D - Thin, net like made up of connective tissue, rich in blood vessels. Pigment present, red in rabbit, brown or black in man. It reduces internal reflection.

What are the elements that constitute the internal ear, Q. What are the ele...

Q. What are the elements that constitute the internal ear? What are the functions of those structures? In the internal ear there are the semicircular canals and the cochlea. Th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd