Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

How sugar is used in meringues, How sugar is used in Meringues? Egg whi...

How sugar is used in Meringues? Egg whites beaten for a meringue hold air bubbles as the mechanical action of the beaters partly coagulates the egg protein. Sugars make the pro

Explain about ecological species concept, Q. Explain about Ecological speci...

Q. Explain about Ecological species concept? The ecological species concept: This identifies a species as a population that occupies a distinct ecological niche, whence its rep

Adenosine triphosphate (atp), Adenosine triphosphate (ATP) is a general fo...

Adenosine triphosphate (ATP) is a general form in which the energy is stored in living systems; comprises of a nucleotide (with ribose sugar) with three phosphate groups. Energy c

Explain the stool weight and laxation, Explain the Stool weight and laxatio...

Explain the Stool weight and laxation? The amount of stool excreted varies markedly from individual to individual and in an individual over a period of time. Faeces are complex

Measurement of the active ingredient in aspirin pills, Medication delivered...

Medication delivered in the form of a pill contains an active ingredient or ingredients. Beside the drug itself, the pill also contains "fillers". The filler has several functions.

Osmoregulation in marine non-chordate metazoans, Osmoregulation in Marine N...

Osmoregulation in Marine Non-Chordate Metazoans Studies on the osmotic pressure of body fluids of marine organisms have displayed that their internal osmotic pressure is more

Explain nutritional management for neuro trauma patients, Define Feeding an...

Define Feeding and Nutritional Management for Neuro trauma? The main objective of nutritional management is to counteract the hypermetabolism associated with inflammation. The

Describe fruit in which seed attached to one ovary wall, Which of the below...

Which of the below describes the type of fruit characterized as a dry, simple, one-seeded indehiscent (pron: in-deh-HISS-ent) fruit with seed attached to one ovary wall at only one

Explain about riboflavin, Explain about Riboflavin Aqueous solution sh...

Explain about Riboflavin Aqueous solution shows a pronounced green-yellow fluorescence, which is maximal at a pH of about, 6-7 and disappears upon the addition of acids and al

What are the fundamental constituents of the cell membrane, Q. What are the...

Q. What are the fundamental constituents of the cell membrane? The cell membrane is formed of lipids, carbohydrates and proteins. The membrane lipids are phospholipids, a sp

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd