Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Isospora, ciclo vital de la isospora belli

ciclo vital de la isospora belli

Define prevention in the prevalence of overweight or obesity, Define Preven...

Define Prevention in the prevalence of overweight or obesity? It is believed that the increase in prevalence of obesity worldwide is more due to the environment that has become

Investigation of aortic regurgitation by serial testing, Q. Investigation o...

Q. Investigation of aortic regurgitation by Serial Testing? Serial testing is indicated in asymptomatic patients with severe AR and preserved LV function since LV dysfunction m

Blood, How the blood is circulated with the help of Heart?

How the blood is circulated with the help of Heart?

Explain the techniques of operation in post myocardial, Explain the Techniq...

Explain the Techniques of Operation used in post myocardial infarction ventricular septal defect? Normal 0 false false false EN-IN X-NONE X-NONE

Wind-environmental components, Wind Strong current of air is known as w...

Wind Strong current of air is known as wind, it is an important ecological factor as it affects plant life mainly on flat plains, along sea coasts and at high altitudes in moun

Nekton - aquatic ecosystem, Nekton - Aquatic Ecosystem This group cont...

Nekton - Aquatic Ecosystem This group contains animals which are swimmers. The nektons are relatively large and powerful as they have to overcome the water currents. The anima

Explain adverse effects of valacyclovir, Adverse Effects of Valacyclovir  ...

Adverse Effects of Valacyclovir  Valacyclovir is generally well tolerated; adverse effects are similar to those with acyclovir. GI disturbance, headache, rash, CNS effects such

Syngamy and triple fusion, Syngamy and Triple Fusion After traversing...

Syngamy and Triple Fusion After traversing through the stylar region, the ultimate destination of the pollen tube is to reach the female gametophyte and release the male game

Characteristic of callus, Characteristic of Callus The most important ...

Characteristic of Callus The most important characteristic of callus from a functional view point is that abnormal growth has the potential to develop normal roots, shoots and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd