Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Morphological and anatomical evidences of evolution, MORPHOLOGICAL AND ANAT...

MORPHOLOGICAL AND ANATOMICAL EVIDENCES - (i ) HOMOLOGOUS ORGANS - The organs apparently similar or dissimilar in structure and function, but of similar embryonic origi

What is the nucleolus, The nucleolus is a small and optically dense region ...

The nucleolus is a small and optically dense region in the interior of the cell nucleus. It is made of ribosomic RNA (rRNA) and proteins. Single nucleus can have one or more nucleo

What is the genotypical proportion of the gametes, Which is the type of gam...

Which is the type of gamete (for a given trait) produced by a dominant homozygous individual? What is the genotypical proportion of these gametes? What about a recessive homozygous

Indicator organism, a) What are the needsfor an organism to be an indicator...

a) What are the needsfor an organism to be an indicator organism? b)  In Australia, National Parks and coastal beaches attract various visitors during holiday periods.  EPA is

Fermentation, outline the process of yeast fermentation stating all enzymes...

outline the process of yeast fermentation stating all enzymes involved

Ms j, what direct or indirect effect is " acid rain" thought to have on (I)...

what direct or indirect effect is " acid rain" thought to have on (I) lakes, (ii) forests and (iii) buildings

Explain the economics in nutrition, Explain the Economics in Nutrition? ...

Explain the Economics in Nutrition? We mentioned earlier that nutritional problems affect the productivity of the individual, which, in turn affects the productivity of the nat

Epidemiology, The epidemiology of acute rheumatic fever (ARF) is closely co...

The epidemiology of acute rheumatic fever (ARF) is closely connected with that of group-A beta haemolytic streptococcal pharyngitis, both have a maximum incidence in the age group

Self - medication, SELF - MEDICATION - Self medication refers to the us...

SELF - MEDICATION - Self medication refers to the use of medicines without consulting a physician. Self medication may be harmful, rather dangerous. It must be avoided. (i)

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd