Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Explain some food applications of pectin, Explain Some food applications of...

Explain Some food applications of pectin As with other viscous polyanions such as carrageenan, pectin may be protective towards milk casein colloids, enhancing the properties (

Rotential complications of post removal, Rotential complications of post re...

Rotential complications of post removal -Fracture of the tooth , -leaving the tooth unrestorable , or restored with fair prognosis -root perforation , -post breakage, and -

Properties and functions of synapses, Properties and Functions of Synapses ...

Properties and Functions of Synapses There is an interval between depolarisation of the presynaptic terminal and the earliest appearance of a postsynaptic response. This inter

Character displacement and ecological exclusion, Consider two species of or...

Consider two species of organisms, species A and species B. Species A has a population in a community. Another population species B arrives into the same community, rather suddenly

What is fixism, What is fixism? Fixism is the theory about the diversit...

What is fixism? Fixism is the theory about the diversity of life on earth that affirms that the current existent species were identical to species of the past and came out alre

What are the three major types of rna, Q. What are the three major types of...

Q. What are the three major types of RNA? What is meant by heterogeneous RNA? Messenger RNA, or mRNA, transfer RNA, or tRNA, and ribosomal RNA, or rRNA, are the three main type

Bacteriophage vectors, Bacteriophage Vectors Bacteriophages are viruses...

Bacteriophage Vectors Bacteriophages are viruses that attack bacteria. Mainly phage lyses the bacterial cells they infect (lytic phages). But many others may choose to follow e

Systolic dysfunction onset of symptoms, Q. Systolic dysfunction onset of sy...

Q. Systolic dysfunction onset of symptoms? In asymptomatic patients with normal LV function, the rate of progression to symptoms and/or LV Systolic dysfunction is about 4 per c

Define the effect of niacin deficiency on skin, Define the effect of niacin...

Define the effect of niacin deficiency on Skin? Dermatitis is the characteristic feature of the' disease, It is symmetrical in distribution. In early stages, a bright red eryt

Define the streak plate method - pure culture techniques, Define the Streak...

Define the Streak Plate Method - Pure Culture Techniques? The method was developed by Loeffler and Gaffkey in the laboratory of Robert Koch. The streak plate method depends on

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd