Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What is the part of the female reproductive system, What is the part of the...

What is the part of the female reproductive system where fecundation occurs? Fecundation generally happens in the Fallopian tubes but it can also take place within the uterus.

Pathophysiology of acute glomerulonephritis, Pathophysiology   The exac...

Pathophysiology   The exact mechanism of glomerulonephritis  is still under investigation. The dies'ease is characterised by deposition  of immune complexes  consisting of anti

State the concept of type locus interaction, State the concept of type locu...

State the concept of type locus interaction Some of the major contributions included the concept of type locus interaction, the analysis of quantitative as opposed to qualitati

Mycoplasmosis, Contagious bovine pleuropneumonia (CBPP) This is a highl...

Contagious bovine pleuropneumonia (CBPP) This is a highly fatal disease of cattle and of major economic importance in certain tropical countries. It also affects buffaloes, bis

Prevention of overloading the sterilizer, Prevention of overloading the ste...

Prevention of overloading the sterilizer Most sterilizers have a system to notify the operator of mechanical malfunction, but sterilizers cannot notify the operator whether the

Is gene a triplet of consecutive dna nucleotides, Is gene a triplet of cons...

Is gene a triplet of consecutive DNA nucleotides A gene isn't a triplet of DNA nucleotides with their respective nitrogen-containing bases, like CGT or AAG. The nucleotide trip

What is hansen disease, What is Hansen's disease (etiological agent, mode o...

What is Hansen's disease (etiological agent, mode of transmission, clinical manifestations and prevention)? The etiological agent of Hansen's disease is bacteria known as Mycob

Define the term epimerism, Define the Term Epimerism? In addition to D ...

Define the Term Epimerism? In addition to D and L isomerism sugars also exhibit epimerism. Hexoses that differ from each other as a result of variation of H and OH on carbons 2

Why is there little or no grass in the forest, Why is there little or no gr...

Why is there little or no grass in the forest? 1. Because of the presence of the bushy trees close together in the forest, sunlight does not penetrate simply to the ground. Thi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd