Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Determine the categories of latent squint, Determine the categories of Late...

Determine the categories of Latent squint Latent squint category there are five subtypes: 1)  Esophoria 2)  Exophoria 3)  Hypophoria 4)  Hyperphoria 5)  Cyclopho

What is dip stick test, What is Dip Stick Test It is a rapid method of ...

What is Dip Stick Test It is a rapid method of detection of Ketone bodies which you can perform easily. Plastic strips impregnated with a buffered mixture of sodium nitropru

Explain the absorption of itraconazole capsules, Explain The absorption of ...

Explain The absorption of itraconazole capsules It is decreased with concurrent use of drugs that reduce gastric acidity, such as antacids, H2-receptor blockers, proton pump in

Consumptive use values, This means the non-market value of natural products...

This means the non-market value of natural products such as firewood, game and fodder that do not pass through a market or product preparation. Indigenous people in developing cou

What is coelom - body cavity explain, What is Coelom - Body Cavity explain?...

What is Coelom - Body Cavity explain? Among the bilaterally symmetrical organisms, animals have three different types of body plans with respect to body cavities. The term coel

Suprasternal views, These views are obtained by placing the transducer in t...

These views are obtained by placing the transducer in the suprasternal notch with the ridge pointing cephalad. The neck is extended during the suprasternal notch examination. Thi

What is an argument that shows emergence of photosynthetic, What is an argu...

What is an argument that shows that the emergence of photosynthetic beings was crucial for life to reach the marine surface and later the dry land? The Ultraviolet radiation fr

Photosynthesis, how do i prove in a diagram that water is needed for photos...

how do i prove in a diagram that water is needed for photosynthesis

Define nutrition counseling - management of eating disorders, Define Nutrit...

Define Nutrition Counseling - Management of Eating Disorders? Nutrition counseling can be used to accomplish a variety of goals, such as reducing behaviours related to the eati

Protein requirements of school children and adolescents, Determine Protein ...

Determine Protein requirements of school children and adolescents? FAO/WHO/UIW (1985) recommends factorial method to compute their protein requirements. The factorial value is

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd