Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Proteins requirement in dyslipidemia, Q. Proteins requirement in dyslipidem...

Q. Proteins requirement in dyslipidemia? Proteins: While the quantity of protein does not impose any significant impact on the serum lipoproteins, it is the quality of protein,

Define role in protein metabolism and growth, Define Role in protein metabo...

Define Role in protein metabolism and growth? Severe vitamin A deficiency results in abnormal RNA metabolism and protein synthesis and hence interferes with growth. Hence vitam

Radioisotopes, Radioisotopes Radioisotopes are those forms of an elemen...

Radioisotopes Radioisotopes are those forms of an element which exhibit rzdioactivity and so can be used as markers or tracers. For this purpose, we first introduce the radiois

Valve replacement, Valve Replacement Replacement of the diseased valve...

Valve Replacement Replacement of the diseased valve is done. This is done biologic tissue valves or mechanical valves. Three types of biologic tissue valves are used. Aut

Potassium ion can pass easily through cell membranes, In the human body, th...

In the human body, the potassium ion can pass easily through cell membranes, yet the potassium ion concentration is higher inside many cells than it is outside these cells. Could t

What is chroma in soil, What is Chroma in soil Chroma is the relative p...

What is Chroma in soil Chroma is the relative purity or strength of the spectral colour and its numerical value extend from (/0) for neutral colours to (/8) for the strongest e

What is the contraceptive mechanism of the iud, What is the contraceptive m...

What is the contraceptive mechanism of the IUD? The IUD (intrauterine device) is a piece of plastic coated with copper that is inserted within the uterus by a doctor. Copper is

Study giude, how many atoms are H2SO4 compound

how many atoms are H2SO4 compound

Cost due to damage to equipment, Cost due to Damage to Equipment Cost ...

Cost due to Damage to Equipment Cost due to Damage to Equipment, Property etc. Tooling may have to be redesigned, adding cost. Cost due to reduced output and delay

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd