Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Enumerate about the colour vision defects, Enumerate about the colour visio...

Enumerate about the colour vision defects Acquired colour vision defects can occur afkr damage to the optic nerve or macula and in some cases, because of blue blindness in old

Functions of the cartilages in the human body, Q. What are a few functions ...

Q. What are a few functions of the cartilages in the human body? Cartilages are responsible for the structural support of the ears and nose. The bronchi and the trachea are als

Chlamydiosis, CHLAMYDIOSIS Amongst various causes of morbidity and mortali...

CHLAMYDIOSIS Amongst various causes of morbidity and mortality chlamydiosis is recognized as one of the important infectious conditions and emerging as threat to the livestock due

Female reproductive system - vagina, V AGIN A - Median, elastic, musc...

V AGIN A - Median, elastic, muscular tube 7.5 cm long. Open into vestibule by vaginal orffice. The lining forms vaginal rugae. Space between vaginal wall & cervix is forn

What is a biologic failure, What is A biologic Failure A biologic Fail...

What is A biologic Failure A biologic Failure can be defined as the inadequacy of the host to establish or to maintain osseointegration. The inability to establish osseoint

What are autotrophic beings? what are heterotrophic beings, What are autotr...

What are autotrophic beings? What are heterotrophic beings? The Autotrophic beings are those that can produce their own food that is that make organic material from inorganic c

Explain defensive proteins, Explain Defensive Proteins These proteins p...

Explain Defensive Proteins These proteins protect against diseases. Antibodies are the example of defensive proteins. These  combat bacteria and viruses. Also, immunoglobulins,

How is retaining wall works, How is retaining wall works? A retaining w...

How is retaining wall works? A retaining wall together with the backfill the wall retains and the soil that supports the wall is a highly indeterminate system. The magnitudes o

Behaviour modifications for weight reduction plan, Define Behaviour and Lif...

Define Behaviour and Life Style Modifications for Weight Reduction Plan? Behaviour and life style modifications are an integral part of the weight reduction plan. They are base

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd