Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Components of ecosystem, An ecosystem consists of two types of components: ...

An ecosystem consists of two types of components: (a)   Abiotic components: This includes the non-living components of the ecosystem. These are physical and chemical fact

.ecology, describe between native and non-native species from the Otay rive...

describe between native and non-native species from the Otay river valley

What is severity and extent of lesion in cad, What is Severity and Extent o...

What is Severity and Extent of Lesion in coronaw artery disease? Apart from the high prevalence, the other disturbing features of CAD in South Asians are the severity and exten

Explain the absorption, Explain the Absorption, Storage and Elimination of ...

Explain the Absorption, Storage and Elimination of thiamin? After a meal, thiamin is found in the intestine in the free form. Its absorption involves two mechanisms- both acti

Define magnesium levels in erythrocytes and lymphocytes, Define Magnesium l...

Define Magnesium levels in erythrocytes and lymphocytes? Magnesium levels in erythrocytes and lymphocytes: These measures appear to provide a more accurate assessment of body M

Explain the determination of nicotinic acid, Determination of Nicotinic aci...

Determination of Nicotinic acid The chemical methods of assay are based on colour reactions of pyridine. Nicotinic acid and nicotinamide are converted by cyanogen bromide into

Define the meaning of behaviour change communication, Meaning of Behaviour ...

Meaning of Behaviour Change Communication Now day's very common term used for giving health education to people and for giving information to bring change in behaviour is Behav

What are the main prophylactic measures against malaria, Q. What are the ma...

Q. What are the main prophylactic measures against malaria? The major preventive measures against malaria are the elimination of the treatment of infected people, vector mosqui

Explain about hypoglycemia, Q. Explain about Hypoglycemia? It is a Gree...

Q. Explain about Hypoglycemia? It is a Greek term: hypo -meaning less; glyc- means sweet; and emia- means "of the blood". It is a condition in which less than normal amount of

Potential disadvantages - digitalis glycosides, Arrhythmias especially in p...

Arrhythmias especially in presence of hypokalemia, lack of mortality benefit. However, their efficacy in reducing the symptoms of heart failure has been established. Digoxin should

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd