Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Explain nutritional support management for gastric cancer, Explain Nutritio...

Explain Nutritional Support Management for gastric cancer? The 'dumping syndrome' can be greatly minimized or prevented by adhering strictly to an antidumping dict. In general,

Explain mitosis a synonym of reproduction, Q Why in few cases is mitosis a ...

Q Why in few cases is mitosis a synonym of reproduction? In some living beings asexual reproduction occurs by many means binary division, budding, grafting, schizogony, etc. In

Interpretation of blood or serum nutrient value in pregnancy, Define Interp...

Define Interpretation of blood or serum nutrient values in pregnancy? Interpretation of blood/serum nutrient values in pregnancy is therefore complex compared to the non-pregn

Explain transition period from renaissance to modern period, Explain Transi...

Explain Transition Period from Renaissance to Modern Period? The transition period from the Renaissance to the Modern period produced many notable workers and much literature.

Name the material used in bioinert, Bioinert Metals:-  Commercially pur...

Bioinert Metals:-  Commercially pure titanium/ titanium alloys Ceramics:-  Aluminum oxide, zirconium oxide

Posterior leaflet-technique of operation, Posterior Leaflet: In the poste...

Posterior Leaflet: In the posterior leaflet a quadrangular excision of the sector involved in the prolapse is done. This may be up to 15-20 per cent of the leaflet. The remaining

Homogeneity to the nucleic acid chains, Q. Do the phosphate and the pentose...

Q. Do the phosphate and the pentose groups give heterogeneity or homogeneity to the nucleic acid chains? What about the nitrogen- containing groups? Supported by that, which of tho

Aortic and pulmonary orifices, These circular orifices are located at the u...

These circular orifices are located at the upper ends of the outflow parts of the left and right ventricles respectively. The pulmonary orifice which is 3 cms, is 0.5 cm larger tha

Explain two capacities and volumes of respiratory, Given four respiratory c...

Given four respiratory capacities (a - d) and four jumbled respiratory volumes of a normal human adult: Respiratory Respiratory capacities volumes. 1.            Residual vol

Can you explain protease inhibitors, Q. Can you explain Protease inhibitors...

Q. Can you explain Protease inhibitors? Ans. Protease inhibitors are the compounds which are found to some extent in cereal grains such as oats, wheat, barley and mai

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd