Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Phylum protoza, how these can be called as acellular?

how these can be called as acellular?

Health conditions, 2. Mr Konarski, 73 years old, lives in a high-level care...

2. Mr Konarski, 73 years old, lives in a high-level care facility. He has dementia of the Alzheimer''s type, osteoarthritis in both knees and ankles, and hypertension, which is con

Explain about vascular cambium, How can the age of a tree be estimated from...

How can the age of a tree be estimated from the analysis of the rings present on a cross section of its stem? For the growth of the tree it is essential to have formation of ne

How do arthropods grow, Q. How do arthropods grow? Due to the presence ...

Q. How do arthropods grow? Due to the presence of exoskeleton the growth of an arthropod is periodical during the growth period the animal loses the exoskeleton, develops and g

What is the type of genetic inheritance of daltonism, What is the type of g...

What is the type of genetic inheritance of daltonism? Is daltonism more frequent in men or in women? What is the physiological explanation for the daltonism? Daltonism is a re

How many hours will the bag last, Mr. Jones I.V. was hung at noon. It is a ...

Mr. Jones I.V. was hung at noon. It is a liter bag and is infusing at 65 ml/hr. How many hours will this bag last?

Spermatogenesis, Spermatogenesis: In the mature male functional sper...

Spermatogenesis: In the mature male functional sperm cells are produced within the seminiferous tubules of the testes. Around the periphery of the seminiferous tubules are l

How does consecutive protein production occur in translation, How many of t...

How many of the same proteins are made at the same time by each ribosome in the translation of one mRNA molecule? How does consecutive protein production occur in translation?

Define the disc electrophoresis, Define the Disc Electrophoresis? Disc ...

Define the Disc Electrophoresis? Disc electrophoresis has improved resolution and strong bands are obtained. It requires a two-gel system and several different buffers. The run

Areas affected in peptic ulcer, Q. Areas affected in peptic ulcer? The ...

Q. Areas affected in peptic ulcer? The areas affected in peptic ulcer (due to erosion) can be: 1. Lower part of the oesophagus. 2, stomach (lesser curvature - an urn, whe

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd