Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Theoretical calculation of calorific value of a fuel, The calorific value o...

The calorific value of a fuel can be theoretically determined by using dulong's formula. It is assumed that heat evolved comes from the combustion of carbon, hydrogen, and sulphur

Describe the meaning of electrical stimulation, Describe the meaning of Ele...

Describe the meaning of Electrical Stimulation Brain stimulation has been used to map connections in the brain and to elicit changes in behaviour. Much of the pioneering work o

Define about the resistant starch, Define about the Resistant Starch? U...

Define about the Resistant Starch? Until 1980's starch was thought to be completely hydrolyzed and absorbed from the small intestine of man, independent of its source, type and

Why isnt the cooking of vitamin c-containing foods, Why isn't the cooking o...

Why isn't the cooking of vitamin C-containing foods appropriate for vitamin C supply? To obtain vitamin C, for example, from an orange dessert, the vitamin-containing food cann

What is its function of pylorus, Q. What is the valve that separates the du...

Q. What is the valve that separates the duodenum from the stomach called? What is its function? The valve that separates the stomach from the duodenum is the pylorus it has the

Run off-water cycle, Run off Some of the rainfall is soaked into the so...

Run off Some of the rainfall is soaked into the soil and excess water flows over the land surface along the natural slope of the area. Run off is the main source of water for l

Safety and First-Aid Procedures, How can a family prevent injuries from a f...

How can a family prevent injuries from a fire in the home

Explain the methodology for seliwanoff test, Explain the Methodology for se...

Explain the Methodology for seliwanoff test? Take 5 ml of seliwanoff's reagent in a test tube. Add 5-6 drops of the glucose solution and heat the mixture to boiling for about 3

Explain phytoestrogens, Phytoestrogens:- A group of compounds considere...

Phytoestrogens:- A group of compounds considered to offer protection against cancer.

Which is the normal sign of the electric charge, Which is the normal sign o...

Which is the normal sign of the electric charge among the two sides of the neuron plasma membrane? What is the potential difference (voltage) generated among these two sides? What

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd