Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Interaction of insect hormones, Interaction of insect hormones in the proce...

Interaction of insect hormones in the process of metamorphosis The organs and the hormones usually included in metamorphosis of insects. This is since despite the fact that t

Origin of cell wall, Origin of Cell Wall - The cell wall is product ...

Origin of Cell Wall - The cell wall is product of cytoplasm. The cytoplasmic organelles such as endoplasmic reticulum, golgi apparatus play a very important role in the f

Defective extra-preputial protrusion of the penis, Defective extra-preputia...

Defective extra-preputial protrusion of the penis This defect is a result of hypoplasia or a defective penile erection due to a congenital mucosal fold – the frenulum - betwee

Explain adverse effects of emtricitabine, Explain Adverse effects of Emtric...

Explain Adverse effects of Emtricitabine  Emtricitabine can cause hyperpigmentation of the palms and soles, particularly in dark-skinned patients. Because emtricitabine is also

Threshold value of different larval tissues, Threshold Value of Different L...

Threshold Value of Different Larval Tissues Threshold value of dissimilar larval tissues for the thyroid hormone concentration One of the main problems of metamorphosis is

Explain what is probing depth, Q. Explain What is Probing Depth? This p...

Q. Explain What is Probing Depth? This parameter is applicable to one stage implants when they are evaluated prior to prosthetic phase and used to evaluate the health of the im

Cell surface junctions, CELL SURFACE JUNCTIONS (1 )      Desmosomes (...

CELL SURFACE JUNCTIONS (1 )      Desmosomes (Maculae adherence) - Thickened circular areas on P.M. of adjacent cells with radiating fibrils in cytoplasm. These fibrils calle

Zoology, classification mollusca

classification mollusca

Explain supravalvular aortic stenosis murmur, Explain Supravalvular aortic ...

Explain Supravalvular aortic stenosis murmur? Supravalvular Aortic Stenosis Murmur : Characteristic: Murmur may be loudest in 1st Right ICS. It isn't associated with systolic

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd