Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Gastrointestinal tract function , Gastrointestinal Tract Function: As...

Gastrointestinal Tract Function: As a result of burn  injury acute gastric dilation occurs, creating abdominal distention and  regurgitations. Malabsorption occurs secondary

What is gastrulation, What is gastrulation? How during gastrulation are the...

What is gastrulation? How during gastrulation are the first two germ layers formed? What are these germ layers? Gastrulation is the process by which a portion of the blastula w

Define modes or techniques for chromatographic separation, Define Modes or ...

Define Modes or Techniques for Chromatographic Separation In practice, chromatographic separation may take one of these modes or techniques:   Paper chromatography (in w

Factors affecting normal blood sugar levels, Q. Factors Affecting Normal Bl...

Q. Factors Affecting Normal Blood Sugar Levels? Earlier in our discussion, we learnt that insulin is the most important factor responsible for normal blood sugar levels. Now we

Explain biochemical investigation, Explain Biochemical investigation Bi...

Explain Biochemical investigation Biochemical  investigations:  These help  to  reveal nutrients and metabolites in blood and /or urine, and/or faeces that indicate an infectio

What are the three main arthropod classes constituted, How are the excretor...

How are the excretory systems of the three main arthropod classes constituted? In crustaceans a pair of excretory organs known as green glands exists. The green glands collect

Determine protein needs during pregnancy period, Determine Protein needs du...

Determine Protein needs during pregnancy period? Altogether, 925 g of protein are deposited in a normal foetus and maternal accessory tissues and considering the dietary protei

Excretion, what are the excretory organs of birds

what are the excretory organs of birds

What is the inactivation of the x chromosome?what is a barr, What is the in...

What is the inactivation of the X chromosome? What is a Barr body? The Inactivation of the X chromosome is a phenomenon that occurs in women. Ever since women have two X chromo

What is the role of vitamin k in the blood coagulation, Q. What is the orga...

Q. What is the organ where most of the clotting factors are produced? What is the role of vitamin K in the blood coagulation? Most of the clotting factors are produced in the l

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd