Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Which enzyme acts on pyruvate in mitochondria, Which enzyme acts on pyruvat...

Which enzyme acts on pyruvate in mitochondria and converts it to acetyl CoA?Name its components and cofactors associated with it. Pyruvate dehydrogenase complex acts on pyruvate

Carbohydrates, Carbohydrate - contains Carbon , Hydrogen , and Oxygen ...

Carbohydrate - contains Carbon , Hydrogen , and Oxygen with a general formula of C x (H 2 O) y Simple sugars à monosaccharides Oligosaccharide à sugars containing

Explain pasteurization - method of food preservation, Explain Pasteurizatio...

Explain Pasteurization (temperature below 100° C) - method of food preservation? Pasteurization is a heat treatment that kills a part but not all the microorganisms present and

What is a cytoskeleton, What is a cytoskeleton? What are its main constitue...

What is a cytoskeleton? What are its main constituents in animal cells? Cytoskeleton is the cytoplasmic structure that handles the cell, keeps its shape and fixates and moves t

Sublimation-evaporation-transpiration-water cycle , Sublimation is the pr...

Sublimation is the process by which solid water changes directly to vapour phase without passing through the intervening liquid phase. The gradual disappearance of flakes of ice

Animal kingdom, classification of phylum protozoa upto groups

classification of phylum protozoa upto groups

Define glycogen , A glycogen molecule having entirely of glucose uni...

A glycogen molecule having entirely of glucose units, many of that are linked in long chains through α1-4 bonds.  Furthermore,  every  10  units  or  so,  the  chain  is branched

Determine what is the most significant step, Analyze the similarities and d...

Analyze the similarities and differences between chemosynthesis and photosynthesis. Determine what you believe is the most significant step in regard to harnessing energy within ea

Types of fertilization, TYPES OF FERTILIZATION - On the basis of site o...

TYPES OF FERTILIZATION - On the basis of site of fertilization, it is of two types - 1. External fertilization        2. Internal fertilization 1 .       EXTERNAL FERTILIZ

How can we assess the nutritional status of a chd infant, How can we assess...

How can we assess the nutritional status of a CHD infant? Various assessment methods can be used, particularly anthropometrical -weight, length (height), head circumference and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd