Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Safety and First-Aid Procedures, How can a family prevent injuries from a f...

How can a family prevent injuries from a fire in the home

Mutualist exploration of cellulose digestion, Q. What is meant by "mutualis...

Q. What is meant by "mutualist exploration of cellulose digestion", a phenomenon that occurs in some mammals and insects? Herbivorous animals eat great amounts of cellulose a s

Define pre-exercise or pre-event meal for athletes, Define Pre-Exercise or ...

Define Pre-Exercise or Pre-Event Meal for athletes? Suitable foods in adequate quantities at all times should be consumed but before the event, strategies to fuel up the energ

Deficiency diseases-osteomalacia, Osteomalacia Similar to rickets in yo...

Osteomalacia Similar to rickets in young growing animals, osteomalacia is a disease of mature animals caused by absolute or relative deficiency of any one or combination of cal

Draw a graph for an iv multiple infusion of a drug, Draw A graph for an IV ...

Draw A graph for an IV multiple infusion of a drug, and label on the graph where the trough (predose) blood draw would be collected and where the peak (postdose) blood draw would b

Describe the advantages and disadvantages of insulin pump, Describe the Adv...

Describe the Advantages and Disadvantages of insulin pump Advantages - Insulin pumps deliver more precise amounts of insulin. This supports control over blood sugar level,

Explain the concepts of chromosome, How are the concepts of chromosome, chr...

How are the concepts of chromosome, chromatin and chromatids related? In which phase of the cell cycle does DNA duplicate? Chromatin is a set of filamentous DNA molecules dispe

How did gifford pinchot view nature, How did muir's impression of man's rel...

How did muir's impression of man's relationship with nature differ from Susan Fenimore coopers? And How did Gifford Pinchot view nature?

What do you mean by tubular secretion, Q. What is tubular secretion? What a...

Q. What is tubular secretion? What are some examples of substances secreted through the renal tubules? Uric acid, Ammonia, potassium bicarbonate and hydrogen ions, bases and me

Characteristics of the digestive system of earthworm, Q Which are the organ...

Q Which are the organs and characteristics of the digestive system of earthworms related to the kind of diet of these animals? Small organisms ingested together with soil parti

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd