Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Biotechnology, How does bisulfite sequencing work ?

How does bisulfite sequencing work ?

What would be the progeny of these crosses, Suppose that you are raising Do...

Suppose that you are raising Downton wombats, carefully because they bite when teased.You notice that some of your wombats have white spots, whereas others have solid coats. What t

Enzymes of endoplasmic reticulum, ENZYMES OF E.R. Numerous enzymes have...

ENZYMES OF E.R. Numerous enzymes have been found associated with its membranes, Glucose-6-phosphatase is the marker enzyme of E.R. The chief being those required for the synt

Explain nutritional and functional role of aluminium, Minerals :- Aluminium...

Minerals :- Aluminium                Food Source       Low and variable in foods, component of some antacids and leavening agents Nutritional Functional role Possib

Define about the food production, Define about the Food Production? We ...

Define about the Food Production? We know that agriculture comprises the major source of food production. This is very true in a country like ours where the majority of the pop

Viral diseases of domestic animals, Cattle and buffalo diseases Rinde...

Cattle and buffalo diseases Rinderpest: Rinderpest is the most destructive of the virus diseases of cloven-footed animals, viz. cattle, buffaloes, sheep, goats, pigs and wil

Classification of multicellular animals, Classification of Multicellular An...

Classification of Multicellular Animals The multicellular animals (Animalia) originated from the simpler protozoan protists. You know the simpler multicellular animals further

TISSUES, difference between axon and cyton

difference between axon and cyton

Thumb rule for dietary management, Q. Thumb rule for dietary management? ...

Q. Thumb rule for dietary management? The thumb rule for dietary management is to advice the patient to try to cut down or avoid:  Red meats. Organ meats such as br

Explain signal hypothesis, A classical secretory protein vary from a cytoso...

A classical secretory protein vary from a cytosolic protein by having a sequence about 13-35 amino acids long at its N-terminal end called as a signal peptide or signal sequence.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd