Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Altered fat metabolism - metabolic response to injury, Altered Fat Metaboli...

Altered Fat Metabolism - Metabolic Response to Injury? The stored fat deposiis are mobilized and oxidized at a high rate in order to support hyper metabolism and increased gluc

What are d-glucose and d-galactose, D-glucose differs from D-galactose onl...

D-glucose differs from D-galactose only in the arrangement around carbon 4. Therefore D-glucose and D-galactose are- Select one: a. enantiomers b. epimers c. mirror ima

What is a centimorgan, What is a centimorgan? Centimorgan, or recombina...

What is a centimorgan? Centimorgan, or recombination unit, by convention is a distance among two linked genes that corresponds to 1% of recombination frequency of these genes.

Scientific methord, how adoctor dicide a sickness of a patiant

how adoctor dicide a sickness of a patiant

What is the explanation for the bleeding, What is the explanation for the b...

What is the explanation for the bleeding that accompanies menses? The hemorrhage that accompanies menses happens because the endometrium is a richly vascularized tissue. The r

Agriculture - degradation of ecosystem, Agriculture - Degradation of Ecosys...

Agriculture - Degradation of Ecosystem Agriculture whether traditional or modern involves intervention and modification of the natural ecological systems. Ever since man has s

Adaptation, ADAP T A TIO N - Characters that make an organism to...

ADAP T A TIO N - Characters that make an organism to adjust well and suited to its way of life. Variation occur in living organism due to change in environment. Th

Ecology, what is the importance to study the tolerance range in real-life...

what is the importance to study the tolerance range in real-life situations?

Epithelial tissues., function , structure and lo of location of germinal e...

function , structure and lo of location of germinal epithelium

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd