Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Conditioned reflex , CONDITIONE D REFLEX - Response which is achiev...

CONDITIONE D REFLEX - Response which is achieved by training is conditioned reflex. I. P. Pavlov in 1920 displayed it by experimenting on dog. These are voluntary in

Excretion in roundworm, EXCRETIO N IN ROUNDWORM - In ascaris 4 coelomo...

EXCRETIO N IN ROUNDWORM - In ascaris 4 coelomoducts present, attached to each other by canaliculli in front of controling cell i.e. Rennete cell. Excretion materials are gi

Define criteria for assessment of pyridoxine status, Define Criteria for As...

Define Criteria for Assessment of Pyridoxine Status? Vitamin B 6 status is most appropriately evaluated by using a combination of indicators,  namely plasma PLP concentration,

Prepare a dichotomous key, Prepare a dichotomous key the following organism...

Prepare a dichotomous key the following organisms, ant, butterfly, fly, beetle, grass hopper, wasp, ladybug, roach and dragonfly

Accuracy of stress echocardiography, Q. Define Accuracy of Stress Echocardi...

Q. Define Accuracy of Stress Echocardiography? The accuracy of stress echo tests for the detection of coronary artery disease is expressed as the sensitivity and specificity of

Explain the term kwashiorkor, Explain the term Kwashiorkor? The term Kw...

Explain the term Kwashiorkor? The term Kwashiorkor means the 'disease the first child gets when the second baby is born', that is, 'the sickness of the deposed child'. Thus, th

Transport of substances done across the bryophyte tissues, Q. How is the tr...

Q. How is the transport of substances done across the bryophyte tissues? How is this feature related to the general size of these plants? In bryophytes there are no nutrient-co

What are the symptoms of acute pericarditis, Q. What are the Symptoms of ac...

Q. What are the Symptoms of acute pericarditis? Chest Pain Chest pain is the most important symptom. It is retrosternal in location and patient usually locates the site o

Main prophylactic measures against hookworm disease, Q. What are the main p...

Q. What are the main prophylactic measures against hookworm disease? The major prophylactic measures against hookworm disease are to avoid walking barefoot on soils suspected o

Pox diseases, Pox diseases Small-pox in human beings and pox in a few ...

Pox diseases Small-pox in human beings and pox in a few animal species are closely related to each other. It is shown by the fact that the vaccine for the prevention of small

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd