Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Explain the main function of the digestive system, Explain the main  funct...

Explain the main  function of the digestive system The major function of the digestive system is to ingest the food materials, digest it to absorbable end products, absorb the

Explain characteristics that make breastfeeding beneficial, Explain charact...

Explain characteristics that make breastfeeding beneficial to the infant? We have listed some characteristics that make breastfeeding beneficial to the infant: • Mature milk

Determine the part of an actuating signal, Which of the following serves as...

Which of the following serves as an actuating signal, or as part of an actuating signal, in a negative feedback system? A. Action potentials in diaphragm skeletal muscle fibers

How does the intensity of facilitated diffusion differ, How does the intens...

How does the intensity of facilitated diffusion vary in relation to the concentration of the moved substance? What is the limiting factor? Like simple diffusion facilitated dif

Zoonotic diseases-influenza, Influenza Influenza is an acute infectious di...

Influenza Influenza is an acute infectious disease caused by influenza viruses of genus Orthomyxovirus in family Orthomyxoviridae. The name Influenza is derived from an Italian ph

Glycogen, G L YCOGEN Polymer of a-D-glucose. It has 5000-30000 uni...

G L YCOGEN Polymer of a-D-glucose. It has 5000-30000 units of a-D-glucose. Glycogen is glucosan homopolysaccharide which is the major reserve food of animals, fungi and

Osmoregulation, how is water lost from respiratory surface

how is water lost from respiratory surface

Enlist the modalities available for hand wash, Q. Enlist the modalities ava...

Q. Enlist the modalities available for hand wash? Modalities available for hand wishing are a) 2-4% Chlorhexidine b) 0.3-1 %Triclosan c) 0.6% Parachlorometaxylenol (PC

Phylum protozoa, what is holozoic, holophytic, saprozoic nutrition

what is holozoic, holophytic, saprozoic nutrition

Myocarditis, Myocarditis Myocarditis is inflammation of the myocardiu...

Myocarditis Myocarditis is inflammation of the myocardium, of the heart muscles. i) Causes Infection: . Wrus, bacteria, fungus, parasites Non-infection: Radi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd