Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Define initiation phase - mechanism of protein synthesis, Define Initiation...

Define Initiation phase - mechanism of protein synthesis ? The assembly of a ribosome on an mRNA molecule at the correct start point, the initiation codon. Three initiation fac

Illustrate the major events of the final mitotic period, Q. What are the ma...

Q. What are the major events of the final mitotic period? The final mitotic phase is the telophase. In the telophase the following events occur decondensation of chromosomes ea

Define the term - dna polymerase, Which of the following best describes the...

Which of the following best describes the reasons why the sliding clamp is able to confer processivity on DNA polymerase and not DNA primase? A. The sliding clamp coats the tem

Glucose is a good source of energy for bacteria, Why is glucose such a good...

Why is glucose such a good source of energy for bacteria? 1) Glucose contains six oxygen atoms, which can be used for oxidative phosphorylation and the generation of many ATP molec

Differences between mitosis and meiosis, DIFFERENCES BETWEEN MITOSIS AND...

DIFFERENCES BETWEEN MITOSIS AND MEIOSIS    EVENTS  MITOSIS  MEIOSIS  Occurrence  In all the body cells including

Rbc & wbc, difference between RBC and WBC for homework

difference between RBC and WBC for homework

Interior of the left atrium - heart, The left atrium is a thin walled cavit...

The left atrium is a thin walled cavity. Most of the wall is smooth. Musculi pectinati are present only in the auricle of the atrium. The interatrial septum separates the cavity of

State the principles of behaviour change communication, Principles of behav...

Principles of behaviour change communication - BCC should be integrated with program goals from the starting. BCC is a necessary part of diabetes prevention, care and support p

Explain the scaling from individuals to ecosystems, Explain the Scaling fro...

Explain the Scaling from individuals to Ecosystems? Models that explain how individual organisms acquire energy and materials, and how they use them for survival, growth and re

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd