Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Types of surgery, Types of Surgery :  Tricuspid valvotomy is done as an op...

Types of Surgery :  Tricuspid valvotomy is done as an open procedure at the end of surgery on mitral and/or aortic valve. It can be done on an arrested heart or on a beating heart

What are mineral salts, What are mineral salts? Where in living beings can ...

What are mineral salts? Where in living beings can mineral salts are found? Mineral salts are simple inorganic substances made of metallic chemical elements, such as iron, sodi

Explain the process of angioplasty, Q. Explain the process of Angioplasty? ...

Q. Explain the process of Angioplasty? Inflation of stenotic segment causes stretching of the vessel, fracture of the intimal plaque, partial disruption of the media and adven

Symptoms of serum sickness, Symptoms contain fever, weakness, rashes, with ...

Symptoms contain fever, weakness, rashes, with erythema and edema. Serum sickness depends on the immune difficult formed and the size of the complexes.

Explain about the conjugated proteins, Explain about the Conjugated protein...

Explain about the Conjugated proteins? The phospho proteins and the metallo proteins are loose (as with phosphate carrying protein) or tight (as with the phosphate in casein or

Explain malnutrition, Explain Malnutrition Malnutrition, impaired immun...

Explain Malnutrition Malnutrition, impaired immunity and infection can form a triad or vicious cycle, as illustrated in Figure, which works synergistically and thus worsens the

What is metagenesis, What is metagenesis? What are the other names of this ...

What is metagenesis? What are the other names of this process? Metagenesis is the type of life cycle in which there are two dissimilar forms of individuals of the same species,

Implementation of nursing care in acute rheumatic fever, Implementation of ...

Implementation of Nursing Care Provide Bed Rest and Comfort   Your major role as a nurse is to provide bed rest to the child and assist the child and parents to understa

Acrylamide gel, Acrylamide gel  is a polymer gel used for electrophoresis o...

Acrylamide gel  is a polymer gel used for electrophoresis of DNA or protein to measure their sizes (in the daltons for proteins, or in base pairs for DNA). See "Gel electrophoresis

Blood protozoan and ricketsial diseases - trypanosomiasis, B l oo d Prot...

B l oo d Protozoan and Ricketsial Diseases T r y p a n o s o m i a si s It is also known as surra in equines and tibarsa in camel and results in intermitte

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd