Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What is plant coleoptile, What is plant coleoptile? Why does the removal of...

What is plant coleoptile? Why does the removal of the coleoptile extremity disallow plant growth? Coleoptile is first (one or more) aerial structure of the sprouting plant that

How does the inflammation mechanism work, Q. How does the inflammation mech...

Q. How does the inflammation mechanism work? When some tissue injury other vasoactive and occurs histamine substances (called mediators of inflammation) are released, they caus

Define phase of the cell cycle, Q. Generally which phase of the cell cycle ...

Q. Generally which phase of the cell cycle has longer duration? The mitotic phase has quite a shorter length and the interphase comprises approximately 4/5 of the cell cycle.

Define determinants of food security - food access, Define Determinants of ...

Define Determinants of Food Security - Food Access? Food access is linked to its affordability. Food access is ensured when households and all individuals within them have adeq

Which harmone is not associated with male reproduction, Which of the below ...

Which of the below is NOT hormone associated with male reproductive physiology: a) Prolactin b) Testosterone c) Interstitial hormone d) Follicle-stimulating hormone

Respiration.., different types of respiration system in different organisms...

different types of respiration system in different organisms

What is frog central nervous system, What is frog central nervous system ...

What is frog central nervous system Consider Neuron B in the frog central nervous system whose plasma membrane has a newly discovered ligand-gated ionotropic receptor, named th

Associated foods with escherichia coli, Q. Associated Foods with escherichi...

Q. Associated Foods with escherichia coli? Associated Foods: E. coli is the etiologic agent of food poisoning involves variety of foods such as cream pie, mashed potatoes, cr

Explain implant mobility and discomfort - implant interface, Implant Mobili...

Implant Mobility and Discomfort Implant mobility is an indication of the lack of osseointegration. Even if periimplant disease has progressed relatively far, implants may still

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd