Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What do biomass pyramids represent, What do biomass pyramids represent? ...

What do biomass pyramids represent? Biomass pyramids show the sum of the masses of the individuals that participate in each trophic level of a food chain.

Phases of the cardiac cycle, The phases of the cardiac cycle are: 1)  At...

The phases of the cardiac cycle are: 1)  Atrial Systole This begins with the P-wave of the ECG. The atrio-ventricular valves are open and the ventricles are relaxed (diastole

Test tube baby, TEST TUBE BABY - Ova are fertilized in laboratory di...

TEST TUBE BABY - Ova are fertilized in laboratory dish (in vitra) containing a nutrient broth . It may be artificial insemination donor (AID) / Artificial insemination h

What are the signs of myocardial disease, Q. What are the signs of myocardi...

Q. What are the signs of myocardial disease? One manifestation of congestive cardiac failure is decreased exercise tolerance depending on the level of compensation. This leads

What is biochemical characteristics, What is Biochemical Characteristics? ...

What is Biochemical Characteristics? In the last section we have learnt about the importance of biochemical tests. It must be clear now that biochemical tests are used to -

Bacteria, wine turns sour beause of the action of which bacteria? aerobic o...

wine turns sour beause of the action of which bacteria? aerobic or anerobic?

Bacteria classified according to their need for oxygen, How are bacteria cl...

How are bacteria classified according to their need for oxygen? According to their necessity of oxygen bacteria are classified into:- a) Anaerobic (those that survive withou

Define about the deficiency of cyanocobalamin, Define about the Deficiency ...

Define about the Deficiency of cyanocobalamin? Malabsorption of vitamin B 12 can occur at several points during digestion. By far, the most important condition resulting in v

What is an oligopeptide, Q. What is an oligopeptide? How is it differing fr...

Q. What is an oligopeptide? How is it differing from a polypeptide? Peptide is the molecule formed by the union of amino acids through the peptide bond. Oligopeptide is a pepti

Physical concepts of plant water relation - diffusion, Physical Concepts of...

Physical Concepts of Plant Water Relation - Diffusion Diffusion is a spontaneous process that leads to net movement of a substance from a region of higher concentration to a r

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd