Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Procedure for use microbiological laboratory equipment, Define Procedure fo...

Define Procedure for use Microbiological Laboratory Equipments? Now carry out this activity following the steps given herewith: 1. Observe each instrument (as mentioned abov

What is cyanosis, What is Cyanosis ? Cyanosis: Cyanosis may be peripher...

What is Cyanosis ? Cyanosis: Cyanosis may be peripheral or central. Peripheral cyanosis almost exclusively involves lips and extremities. Normal neonates may have bluish extrem

Determine the viscosity of solutions, Viscosity Viscosity, as you may ...

Viscosity Viscosity, as you may already know, is associated with fluid flow.  It is the internal friction which tends to bring to rest portions of the fluids moving relative to

How molecular biology change forsenic biology, Explain in 100+ words Why/ho...

Explain in 100+ words Why/how did molecular biology change forsenic biology.

Supplementation to prevention of iron deficiency anaemia, Define Supplement...

Define Supplementation to prevention of iron deficiency anaemia? Supplementation with low doses of iron is necessary to prevent anaemia in particular groups of people. Fortifie

What is the intracellular digestion, Q What is the intracellular digestion?...

Q What is the intracellular digestion? Cellular digestion or Intracellular digestion is the breaking in the interior of the cell of big molecules coming from outside or even fr

Cation saturation and nutrient absorption by plants, Cation Saturation and ...

Cation Saturation and Nutrient Absorption by Plants The availability of adsorbed cations is not always so easy as the above explanation might suggest. This is because, several

Explain some side effects of carbohydrate loading, Explain some side effect...

Explain some side effects of carbohydrate loading? Some potential side effects of carbohydrate loading are: Muscle , stiffness Diarrhoea Chest Pain Depres

What is the heterotrophic hypothesis on the origin of life, What is the het...

What is the heterotrophic hypothesis on the origin of life? As per to the heterotrophic hypothesis the first living beings were very simple heterotrophic organisms that is not

Microbiology, control of microorganisms by chemical method.

control of microorganisms by chemical method.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd