Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Advice on dischargeperi operative problems, Advice on Discharge :  Patient...

Advice on Discharge :  Patients are allowed to go home on 8th or 9th day. It could be even earlier after off pump coronary artery surgery (OPCAB). They should gradually increase t

Thymus, THYMU S - It is derived from the endoderm of the embryo. S...

THYMU S - It is derived from the endoderm of the embryo. Structur e . The thymus gland is located in the upper part of the thorax near the heart. It is a soft, pinkish, b

Speculate why stoma in the lower epidermis, Carbon dioxide needed for photo...

Carbon dioxide needed for photosynthesis enters the leaf via the stomata but water is also lost when these pores are open. Water is often limiting and to limit water loss through s

Explain virus envelope, Virus envelope is known as: 1.  Capsid 2.  Vi...

Virus envelope is known as: 1.  Capsid 2.  Virion 3.  Nucleoprotein 4.  Core Capsid

Explain the regulation of breathing and blood pressure, Which is the brain ...

Which is the brain region responsible for the regulation of breathing and blood pressure? The neural regulation of breathing, blood pressure and other physiological parameters

What is the water cycle, Q. What is the water cycle? The water cycle re...

Q. What is the water cycle? The water cycle represents the recycling and circulation of water in nature. The Liquid water on the planet surface is heated by the sun and turns i

How many respectively are genotypical and phenotypical forms, In F2 generat...

In F2 generation of a hybridization for a given trait conditioned by a pair of alleles T and t, according to Mendel's first law what are the genotypes of each phenotypical form? An

What are the four types of weak bonds, What are the four types of weak bond...

What are the four types of weak bonds, and how do they differ from each other and from covalent bonds? When you eat a salad with lettuce, croutons, hard-boiled egg, bacon bits,

Explain treatment options for ailing and failing implants, Treatment option...

Treatment options for ailing and failing implants are varied. The clinician should start conservatively and progress to more aggressive therapy. The overall goal of therapy is

Define chagas and arrhythmogenic right vent cardiomyopathy, Chagas' Cardiom...

Chagas' Cardiomyopathy It is common in south and Central America and is caused by Trypanosoma cruzi. Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) It is mark

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd