Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Procedures for diagnosis - restriction enzyme analysis, R e striction...

R e striction enzyme analysis: The restriction endonuclease analysis of viral DNA fragments or DNA fingerprinting discovered in 1970s has revolutionized the study o

Transport of small molecules, The internal composition of the cell is maint...

The internal composition of the cell is maintained because the plasma membrane is selectively permeable to small molecules. A lot of biological molecules are unable to distribute b

Active transport during membranes, Q Which are the molecules that make poss...

Q Which are the molecules that make possible active transport during membranes? Active transport is prepared by specific membrane proteins. These proteins are known as "pumps"

Functional difference between neurons and glial cells, Q. What are the func...

Q. What are the functional differences between neurons and glial cells? Neurons and Glial cells are the cells that form the nervous system. Neurons are cells that have the func

Explain counseling strategies, Counseling Strategies The counseling str...

Counseling Strategies The counseling strategies which may serve  lo be useful are described herewith. Individual Counseling: Individual counseling is personal counseling.  T

What resources are competed for by animals, What resources are competed for...

What resources are competed for by (a) animals, (b) plants?  (a) Animals compete for food, mates and shelter.  (b) Plants compete for light, water and minerals.

Haemodynamics of tricuspid regurgitation, Q. Haemodynamics of Tricuspid reg...

Q. Haemodynamics of Tricuspid regurgitation? Right Atrial pressure tracing shows a prominent ‘v' wave and these cannot be appreciated in a patient with atrial fibrillation. RV

Screening dna libraries, Genomic  libraries  are  screened  by  hybridizati...

Genomic  libraries  are  screened  by  hybridization with  a  DNA probe which is complementary  to component of the nucleotide  sequence  of the desired gene. The problem should be

Define the term ancestral characteristic, Define the term Ancestral charact...

Define the term Ancestral characteristic A character shared by all members of a taxonomic group of organisms (taxon) and used to define the unique nature of the group. The cha

Define colorimetric method - 2, Define Colorimetric Method - 2, 4 Dinitroph...

Define Colorimetric Method - 2, 4 Dinitrophenylhydrazine Method? We shall use this method in estimating vitamin C in a given sample in the laboratory. Here, let us look at the

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd