Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Gametes, examples of gametes

examples of gametes

Female reproductive system - vagina, V AGIN A - Median, elastic, musc...

V AGIN A - Median, elastic, muscular tube 7.5 cm long. Open into vestibule by vaginal orffice. The lining forms vaginal rugae. Space between vaginal wall & cervix is forn

Explain the two forms of hemicellulose, Explain the two forms of hemicellul...

Explain the two forms of hemicellulose There are two forms of hemicellulose - Hemicellulose A and B - Hemicellulose A is precipitated upon neutralization of an alkaline extract

What is autoclave sterilization, Q. What is Autoclave sterilization? Wo...

Q. What is Autoclave sterilization? Word "autoclave" means self locking and is used to denote an apparatus that sterilizes by use of steam under pressure. It operates on same

What is global warming, What is global warming? Global warming is the e...

What is global warming? Global warming is the enhance in the temperature of the planet due to accumulation of some gases in the atmosphere, especially gases that retain the sol

Bile acid sequestrants for coronary prevention, These are safe and free of ...

These are safe and free of systemic side effects. However, gastrointestinal side effects are common, and compliance is poor. The average LDL decreases by approximately 15 per cent

Exon, Exon are those parts of a genomic DNA sequence which will be represe...

Exon are those parts of a genomic DNA sequence which will be represented in final, mature mRNA t A contiguous segment of the genomic DNA which codes for a polypeptide in the gene.

Describe shunts, Q. Describe Shunts? Detection, localization and quanti...

Q. Describe Shunts? Detection, localization and quantification of intracardiac shunts are one of the most important exercises in cardiac catheterization. In most cases a prelim

Logistic equation, In order to define growth limit logistic equation was gi...

In order to define growth limit logistic equation was given by Verhulst. In a given ecosystem, the maximum population that can exit is called carrying capacity (k).  The factors wh

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd