Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Consistently overwatering a potted tomato plant, Consistently overwatering ...

Consistently overwatering a potted tomato plant will eventually kill it. Using the map, suggest why waterlogged soil results in plant death. O2 cannot reach respiring root cells. T

Explain hardy weinberg equilibrium., MN blood group in humans is under the ...

MN blood group in humans is under the control of two co-dominant alleles M and N. Blood typing results of a population having of 1349 individuals showed that:  -  363 persons h

The development of arteriosclerosis, The client was admitted to the hospita...

The client was admitted to the hospital with hypertension (high blood pressure). The development of arteriosclerosis (plaque buildup in the arteries) has increased peripheral resis

Michaelis menten, Regulation of enzymatic action equations for competitive,...

Regulation of enzymatic action equations for competitive, non-competitive, uncompetitive inhibition and mixed reaction

What is the transcription of the gene downstream, A substitution mutation o...

A substitution mutation occurs in the GRE making it unrecongnizable to the glucocorticoid receptor. What impact would this have on the transcription of the gene downstream of this

Explain generation of sound in mvp, Explain Generation of sound in MVP? ...

Explain Generation of sound in MVP? Generation of sound in MVP: These are generated due to sudden tensing of redundant leaflets and elongated of chordae tendinae. Interventions

What do you mean by cytotaxonomu and biosustematics, Q. What do you mean by...

Q. What do you mean by Cytotaxonomu and biosustematics? Towards the end of the 19 th century and in the early years of the 20th century, botanists were faced with a problem of

Explain fungi - nutritional types of microorganisms, Explain Fungi - Nutrit...

Explain Fungi - Nutritional Types of Microorganisms? Fungi are filamentous, eukaryotic microorganisms, ubiquitous in nature. These grow best in dark and moist habitats. Their h

Inhibition model - models of succession, Inhibition Model - Models of Succe...

Inhibition Model - Models of Succession According to this model, succession is very heterogenous because the development at any one site depends on who gets there first. Speci

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd