Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Metazoa, Metazoa In the two kingdom classification, the unicellular 'a...

Metazoa In the two kingdom classification, the unicellular 'animals' used to be clubbed together under a single phylum Protozoa that constituted sub-kingdom - Protozoa. The re

Peculiarities of mitosis - cleavage, Peculiarities of Mitosis - Cleavage ...

Peculiarities of Mitosis - Cleavage From the following you will learn that the mitosis in the phase of cleavage has some striking peculiarities: a) Synchronization of cell

How to identify the metal out of which the wire is made, A wire 50.0 m long...

A wire 50.0 m long and 2.00 mm in diameter is connected to a source with a potential difference of 9.11 V, and the current is found to be 33.7 A. Assume a temperature of 20°C and,

Protoplasmic theory, Protoplasmic Theory The living matter which forms ...

Protoplasmic Theory The living matter which forms the bodies of all living being is a special type of highly organized jelly like viscous semi fluid, and named Sarcode by Dujar

Describe coping strategies, Patient and his family have to cope up with a ...

Patient and his family have to cope up with a critical situation when patient has complications and more so when a patient has to be admitted in a hospital and referred. Some patie

Heparinisation-procedures of oxygenators, Heparinisation :  The patient sh...

Heparinisation :  The patient should be fully heparinised before the start of cardio pulmonary bypass. Baseline activated clotting time is measured (ACT). 3 mg (300 units) per k

Explain about the vascular tissues, Is transportation of gases in tracheoph...

Is transportation of gases in tracheophytes made through the vascular tissues? Carbon dioxide and oxygen are not transported by the xylem or phloem. These gases reach the cells

Explain the blood plasma levels of calcium, Which of the following serves a...

Which of the following serves as a controlled variable in a negative feedback system? A. Levels of hydrogen ions in the interstitial spaces of the brainstem. B. Blood plasma

Explain some weight loss during breastfeeding, Explain some Weight Loss dur...

Explain some Weight Loss during breastfeeding? Some women may want to return quickly to their pre-pregnancy weight. It is important to remember that some women will lose more,

Define the replication of dna strands, Which of the following is a true sta...

Which of the following is a true statement regarding the replication of DNA strands? A. The products of replication contain one double helix made exclusively of parental DNA an

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd