Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Explain the cost utility analysis, Explain the Cost Utility Analysis? C...

Explain the Cost Utility Analysis? Cost utility analysis: Cost utility analysis provides for measurement of health outcomes for a given cost. The health outcomes are measured q

What are the tissues that form the digestive tube wall, Q. From the lumen t...

Q. From the lumen to the external surface what are the tissues that form the digestive tube wall? From the internal surface to the external surface, the digestive tube wall is

Cow-pox (vaccinia), Epidemiology: This infection, although mostly occurrin...

Epidemiology: This infection, although mostly occurring in cows, sometimes also occurs in buffaloes. Under natural conditions, the infection takes place through inoculation by the

What is resective therapy, Resective therapy Is used to reduce pockets,...

Resective therapy Is used to reduce pockets, correct negative osseous architecture and rough implant surfaces and increase the area of keratinized gingival if needed. Apical

Noise pollution, Sound is a main mean of communication and entertainment an...

Sound is a main mean of communication and entertainment and is also very effective alarm system for some animal. A loud and unwanted or unpleasant sound causes discomfort and is ca

Epithelial tissues., function , structure and lo of location of germinal e...

function , structure and lo of location of germinal epithelium

Define classification of carbohydrates - oligosaccharides, Define classific...

Define classification of carbohydrates - Oligosaccharides? Oligosaccharides are short chains of saccharide units and are condensation products of three to ten monosaccharides.

Explain subphylum mandibulata, Subphylum Mandibulata Most of them have ...

Subphylum Mandibulata Most of them have three pairs of walking legs, mandibles, compound eyes, antennas, some with wings. There are four classes. Crustacea - aquatic with

How are radioactive probes useful in dna fingerprinting, How are radioactiv...

How are radioactive probes useful in DNA fingerprinting? Radioactive probes bind to specific fragments in a DNA sample like a donor gene. A probe can identify which bacteria ha

What are the kinds of reproduction that occur in fungi, Q What are the kind...

Q What are the kinds of reproduction that occur in fungi? In fungi there is sexual and asexual reproduction. Fungi reproduce asexually by fragmentation, sporulation and gemmati

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd