Secretory proteins, Biology

Assignment Help:

Proteins destined to be secreted from the eukaryotic cell are synthesized by ribosomes bound to the RER (rough endoplasmic reticulum). As the protein is synthesized it is translocated withthe rough endoplasmic reticulum membrane into the lumen of the rough endoplasmic reticulum where it folds into its last conformation.  The ER then buds off vesicles which handle the protein to the Golgi apparatus also called as the Golgi complex that is shown in the figure. The Golgi has a cis face (where vesicles enter) and a Tran's face (where vesicles leave). Thus the RER vesicles fuse with the cis compartment of the Golgi and releasing the protein into the Golgi lumen.  The protein then moves by the Golgi complex to the Trans compartment being changes en route through the addition of carbohydrate residues (glycosylation,).

 

373_22.png

Figure:  Synthesis and exocytosis of secretory proteins; see text for details. The ribosomes attached to the RER are represents as filled-in circles while the open circles in the lumen of the RER, vesicles and Golgi complex show secretory protein molecules.

 


Related Discussions:- Secretory proteins

Explain clinical stigmata of syndromes in heart disease, Explain Clinical s...

Explain Clinical stigmata of specific syndromes in heart disease? Clinical stigmata of specific syndromes: Evidence of preseilce of chromosoinal anomalies or other syndromes

Protein requirements of school children and adolescents, Determine Protein ...

Determine Protein requirements of school children and adolescents? FAO/WHO/UIW (1985) recommends factorial method to compute their protein requirements. The factorial value is

What is osseointegration in macroscopic biomechanical, Q. What is Osseointe...

Q. What is Osseointegration in macroscopic biomechanical? A fixture is osseointegrated if there is no progressive relative motion between the fixture and surrounding living bon

Economic biology, Economic Biology: This is the study of useful plants and...

Economic Biology: This is the study of useful plants and animals or their products. Economic biology is referred to as economics and human biology. Economics or Human Biology can

Determine the lateral cephalometric skull view, Determine the Lateral Cepha...

Determine the Lateral Cephalometric Skull View The use of this modality is limited in preoperative evaluation in implant placement for advance cases where there is a need for b

Define the calcium toxicity, Define the Calcium Toxicity? Elevated bloo...

Define the Calcium Toxicity? Elevated blood calcium can occur in association with high parathyroid hormone, hyper- or hypothyroid conditions, bone metastasis, vitamin D toxicit

Explain lock and key model, Fischer 's template or lock and key model ...

Fischer 's template or lock and key model According to this model, the catalytic site of the enzyme has a proper conformation compatible to a specific substrate even  in  the a

Explain the objective of cardiac rehabilitation, Explain the OBJECTIVE of C...

Explain the OBJECTIVE of Cardiac Rehabilitation ? After going through this unit, you should be able to: 1 identifies the eligible candidate for cardiac rehabilitation and be

Pharmacognosy, Pharmacognosy :  This is the study of medicinal plants. Phar...

Pharmacognosy :  This is the study of medicinal plants. Pharmacognosy is a kind of the study of medicines which are derived from natural sources. The American Society of Pharmacogn

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd