Scrapie, Biology

Assignment Help:

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".


Related Discussions:- Scrapie

Explain functions of ascorbic acid, Explain Functions of Ascorbic Acid? ...

Explain Functions of Ascorbic Acid? Vitamin C is easily oxidized, and the majority of its functions in vivo rely on this property. It plays a key role in the body's synthesis o

Contamination of the implant body before insertion, Contamination of the Im...

Contamination of the Implant Body before Insertion The implant may be contaminated by manufacturing error, by the operator, from non titanium instrumentation and by the bacteri

What are the five human digestive secretions, What are the five human diges...

What are the five human digestive secretions? Which of them is the only one that does not contain digestive enzymes? The human digestive secretions such as: saliva, gastric jui

What is classic blalock-taussig bt shunt in shunt operations, What is Class...

What is Classic Blalock-Taussig BT Shunt in Shunt Operations ? Subclavian artery, which arises from innominate artery, is anastomosed to pulmonary artery. In a patient with lef

Give an introduction to intensive care, Give an introduction to intensive c...

Give an introduction to intensive care ? Intensive Care Medicine has its origins from the polio epidemic of 1952 in Copenhagen. Patients who suffered respiratory paralysis were

How factors affecting energy expended in physical activity, How Factors Aff...

How Factors Affecting Energy Expended in Physical Activity? Physical activity as we learnt earlier is the second largest component of daily energy expenditure, after BMR. Howev

How is the human karyotype usually represented, Can two normal individuals ...

Can two normal individuals of the same species with sexual reproduction have identical genomes and identical karyotypes? How is the human karyotype usually represented? Except

Prevention of iron deficient anaemia, Prevention   You as nurse needs t...

Prevention   You as nurse needs to ensure that iron supplementation  is given to children who are at risk for iron deficiency.  Iron supplementation  should start between 4 and

Explain the type I diabetes mellitus, What the difference is between type I...

What the difference is between type I diabetes mellitus and type II diabetes mellitus? Type I diabetes, also called as juvenile diabetes, or insulin-dependent diabetes (this na

Microbiology, different applications of microbiology

different applications of microbiology

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd