Scrapie, Biology

Assignment Help:

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".


Related Discussions:- Scrapie

Define measuring body composition- multiple isotope dilution, Define measur...

Define measuring body composition- Multiple isotope Dilution? Multiple isotope dilution (Total and extracellular body water): It is based on the principle that certain substanc

Peculiarities of mitosis - cleavage, Peculiarities of Mitosis - Cleavage ...

Peculiarities of Mitosis - Cleavage From the following you will learn that the mitosis in the phase of cleavage has some striking peculiarities: a) Synchronization of cell

Explain eicosanoids, Explain Eicosanoids Eicosanoids are the  local h...

Explain Eicosanoids Eicosanoids are the  local hormones formed  by  body  tissues during self-healing responses  to  stimuli.  Eicosanoids are  a family  of  compounds  deriv

Tail - structure of the sperm, Tail - Structure of the Sperm The tail ...

Tail - Structure of the Sperm The tail or flagellum is the longest part of the sperm. By its movement it causes the sperm to swim with the head forward. It consists of a thin

Proteins requirement in diabetes, Q. Proteins requirement in diabetes? ...

Q. Proteins requirement in diabetes? Proteins: Proteins should be provided in adequate amounts to maintain a normal body composition and prevent depletion of lean tissue mass.

Oxidation of succinate to fimarate, Oxidation of  succinate  to  fimarat...

Oxidation of  succinate  to  fimarate:  This reaction is catalyzed  by succinate dehydrogenase and FAD'  is needed as a cofactor. Malonate, structural of succinate, competitively

What is hemolytic disease of newborn, Questiion 1 List various methods ...

Questiion 1 List various methods used for hemoglobin estimation of donor. Add a note on specific gravity method Question 2 Why is it important to follow safety measures

Explain the limiting factors for the growth of a population, What are the m...

What are the main limiting factors for the growth of a population? The factors that limit the growth of a population can be divided into biotic factors and abiotic factors. The

Define gluconeogenesis, What is gluconeogenesis? Highlight its significance...

What is gluconeogenesis? Highlight its significance giving any two examples Gluconeogenesis (i.e synthesis of new glucose) is the synthesis of carbohydrate from non-carbohydrat

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd