Scrapie, Biology

Assignment Help:

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".


Related Discussions:- Scrapie

What is the typical morphological feature of nematodes, What is the typical...

What is the typical morphological feature of nematodes that differentiates them from platyhelminthes? Nematodes are also called as roundworms. As the name shows they are not fl

Explain adverse effects of cidofovir, Explain Adverse Effects of Cidofovir ...

Explain Adverse Effects of Cidofovir About 25% of patients discontinue cidofovir because of adverse effects such as nephrotoxicity, neutropenia and metabolic acidosis. Iritis,

Can you explain balloon valvuloplasty, Q. Can you explain Balloon Valvulopl...

Q. Can you explain Balloon Valvuloplasty? Whenever feasible valvuloplasty is the treatment modality of choice. One has to make sure that the valve is suitable and expertise to

What is the basic role of botanic garden, Q. What is the basic Role of Bota...

Q. What is the basic Role of Botanic Garden? A botanic garden makes us to simply enjoy the beauty and variety of nature. The pleasure of admiring turns us into good naturalists

What is centrioles in cell structure, What is Centrioles in cell structure?...

What is Centrioles in cell structure? Most cells of higher organisms contain pairs of cylindrical bodies called centrioles, which help to organize microtubules in cell division

Myoglobin, Myoglobin We can build up the structure of haemoglobin by c...

Myoglobin We can build up the structure of haemoglobin by considering a single unit or monomeric form caned myoglobin. This consists of a single polypeptide chain the globin i

Describe the phylum echinodermata in details, Describe the Phylum Echinoder...

Describe the Phylum Echinodermata in details? The Phylum Echinodermata takes its name from two words of Greek origin: "echino," ; which means "prickle" or "spine," and "derma,"

Illustrate the dna fragments using gel electrophoresis, Which of the follow...

Which of the following statements regarding the separation of DNA fragments using gel electrophoresis is false? A. DNA fragments will migrate towards the positively charged ele

Enumerate various factors controlling osseointegration, Q. Enumerate variou...

Q. Enumerate various factors controlling osseointegration? The factors controlling osseointegration are: i) Occlusal load ii) Biocompatibility of the material iii) Imp

Eucaryotic cell structure , Eucaryotic cell structure All eucaryotic c...

Eucaryotic cell structure All eucaryotic cells have a cytoskeleton made up of a network of protein filaments (Figure shown below). This network gives the cell its shape, capac

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd