Scrapie, Biology

Assignment Help:

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".


Related Discussions:- Scrapie

Class holothuroidea, Class Holothuroidea Body cucumber-such as; no ar...

Class Holothuroidea Body cucumber-such as; no arms; no spines; no pedicellariae; ossicles minute and embedded in muscular wall; anus present; tube feet along with suckers; am

Define the growth charts of infant, Define the Growth Charts of Infant? ...

Define the Growth Charts of Infant? Besides identifying growth faltering, growth charts also provide the following information: 1) The growth is considered normal or satisfa

Define about the glutathione peroxidases - selenium, Define about the Gluta...

Define about the Glutathione peroxidases - Selenium? The role of selenium in the cytosolic enzyme, glutathione peroxidase (GSHPx), was first illustrated in 1973. Four selenium

Explain adverse effects of bronchospasm, Adverse Effects of Bronchospasm ...

Adverse Effects of Bronchospasm Nasal and throat discomfort can occur. Bronchospasm, sometimes severe, has been reported uncommonly in patients with reactive airway disease; za

Define bioactive materials, Q. Define Bioactive materials? Bioactive ma...

Q. Define Bioactive materials? Bioactive materials: Certain glasses, ceramics, and glass-ceramics that contain oxides of silicon, sodium, calcium and phosphorus (SiO 2 , Na 2

Different types of stems, Different types of stems (a)  Monocots. Secur...

Different types of stems (a)  Monocots. Secure stems of various plants such as bamboo, sugar cane and corn. Cut every of the stems crosswise with a very sharp knife or razor bl

State about kidney, Which of the following is true for the kidney? A. A...

Which of the following is true for the kidney? A. Aquaporin1 (AQP1) channels are located in both luminal and basolateral membranes of epithelial cells in the descending limb of

What are the ploidies of the new cells, In which meiotic division does the ...

In which meiotic division does the separation of identical chromatids occur? After the end of this process what are the ploidies of the new cells? The separation of identical c

The luria-nebraska neuropsychological battery, The luria-nebraska neuropsyc...

The luria-nebraska neuropsychological battery This procedure was first reported in 1978 in the form of two initial validity studies. Historically, Chirstensen, a student of the

Extraction of the tooth, Extraction of the tooth -In nonstrategic impo...

Extraction of the tooth -In nonstrategic importance -Diseased maxillary second molars with no opposing tooth , or with an opposing tooth in class l or lll occlusion that ar

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd