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RNA editing is the name given to several reactions whereby the nucleotide series on an mRNA molecule should be modified by mechanisms other than RNA splicing. The Individual nucleotides within the mRNA should be change to other nucleotides, erased entirely or additional nucleotides inserted. The result of RNA editing is to change the coding capacity of the mRNA so in which it encodes a variant polypeptide than which really encoded by the gene. An instance of RNA editing in humans is apolipoprotein B mRNA and in liver, the mRNA does not undergo editing and the protein produced after translation is called as apolipoprotein B100 that shows in the figure. In cells of the little intestine, RNA editing causes the conversion of a single C residue in the mRNA to U and in so doing, modify a codon for glutamine (CAA) to a termination codon UAA.
Figure: RNA editing
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