Risk analysis - in-vitro studies, Biology

Assignment Help:

In-vitro studies

Mechanistic  data might be  supplemented by  data  from in-vitro  studies, like  as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though,  data  from in-vitro studies should not  be  used  as  the  sole source of information to predict the human risk.

-  The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics.  Though, such information may not be available in many cases and  the  risk assessment process should  not  be delayed pending development of mechanistic and pharmacokineticldynamic data.

 


Related Discussions:- Risk analysis - in-vitro studies

Explain starch - tests for presence of exoenzymatic activity, Explain Starc...

Explain Starch - Tests for the Presence of Exoenzymatic Activity? Starch is a polymer of glucose linked together by glycosidic bonds. Microorganisms produce hydrolytic enzyme a

Explain the consequences of malnutrition, Explain the Consequences of Malnu...

Explain the Consequences of Malnutrition? Malnutrition manifests itself in terms of illness and death in all age groups. Children, pregnant women, nursing mothers and elderly a

Acclimation and acclimatisation, Normal 0 false false false...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain the torsional failure - root canal test, Explain the Torsional Fail...

Explain the Torsional Failure - Root Canal Test a. Occurs when the tip of the rotating instrument blinds (locked) in the canal while the motor continues to rotate the shank of

Explain negative staining technique, Explain Negative Staining Technique? ...

Explain Negative Staining Technique? Here, a stain has a negatively charged chromophore that is repelled by the negative bacterial surface. It results in indirect staining of m

Human genome initiative, Human Genome Initiative is the collective name fo...

Human Genome Initiative is the collective name for number of projects begun in 1986 by Department Of Energy (DOE) to  (1) create an ordered set of DNA segments from known chrom

How to explain the high level of radiation resistance, Deinococcus radiodur...

Deinococcus radiodurans is a bacterium that was isolated from cooling ponds in and around nuclear power plants. It is highly resistant to ionizing radiation. Propose a hypothesis t

Determine the placental mammalian embryos, Which is the extraembryonic memb...

Which is the extraembryonic membrane whose function is to store nitrogen wastes of the embryo? Is this function present in placental mammalian embryos? The allantois is the ext

Describe the epithelial cells of the kidney proximal tubule, Epithelial cel...

Epithelial cells of the kidney proximal tubule ?   A.  The sodium-glucose co-transporter in the luminal membrane is responsible for the net flux of glucose from luminal space to

How is extracellular digestion related to cellular, How is extracellular di...

How is extracellular digestion related to cellular and tissue specialization? Several of specialized cells and tissues appeared with extracellular digestion to give enzymes and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd