Risk analysis - in-vitro studies, Biology

Assignment Help:

In-vitro studies

Mechanistic  data might be  supplemented by  data  from in-vitro  studies, like  as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though,  data  from in-vitro studies should not  be  used  as  the  sole source of information to predict the human risk.

-  The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics.  Though, such information may not be available in many cases and  the  risk assessment process should  not  be delayed pending development of mechanistic and pharmacokineticldynamic data.

 


Related Discussions:- Risk analysis - in-vitro studies

Cytoplasm plays the most important pathogenetic role, The formation of surf...

The formation of surface blebs caused by ischemia reflects in part plasma membrane injury, but also a sign of cytoplasmic injury. Which filamentous component of the cytoplasm plays

What might explain the pattern, A zoologist is investigating a population o...

A zoologist is investigating a population of squirrels whose coat color is controlled by a single gene whose two alleles (B1 & B2) are codominant. B1B1 individuals are black, B1B2

Legume - development of seeds, Legume - Development of seeds Outer epi...

Legume - Development of seeds Outer epidermis of the ovary usually forms the exocarp of the leguminous pod. Next few cell layers constitute the mesocarp with thick-walled pare

Describe class echinoidea in animal kingdom, Describe Class Echinoidea in a...

Describe Class Echinoidea in animal kingdom? Sand dollars and sea urchins either have flattened disc-like bodies, or are somewhat spherical. While they lack the typical five-ar

Define microscopy and physiological analysis, Dr. Herbert discovers a cell ...

Dr. Herbert discovers a cell and he is convinced it is a plant cell. However, as a student of his genetics class, you do not agree with him. You do not believe in microscopy and ph

Explain the diarrhoeal management strategies, Explain the Diarrhoeal Manage...

Explain the Diarrhoeal Management Strategies? The diarrhoeal management strategies have had a major impact on less than 5 mortality rate. The distribution of ORS packets and ne

Phylum prototozoa subphylums, 1.sarcomastigophora 2.sporozoa 3.cnidospora 4...

1.sarcomastigophora 2.sporozoa 3.cnidospora 4.ciliophora

Diabetes mellitus in the world, Diabetes Mellitus in the World As per t...

Diabetes Mellitus in the World As per the International Diabetes Federation Directory, in 1994 the global burden of the disease was estimated at 110 million. These cases will i

Method to estimate phytochrome, Method to Estimate Phytochrome Since t...

Method to Estimate Phytochrome Since there is no chemical test, the only method available to test and estimate phytochrome is the spectrophotometric method. Firstly, the diffe

Why diabetics patient should have vegetables every day, Why Diabetics patie...

Why Diabetics patient should have Vegetables every day Diabetics should have vegetables every day. Fresh vegetables are to be preferred because they have less fats and salt. Da

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd