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In-vitro studies
Mechanistic data might be supplemented by data from in-vitro studies, like as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though, data from in-vitro studies should not be used as the sole source of information to predict the human risk.
- The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics. Though, such information may not be available in many cases and the risk assessment process should not be delayed pending development of mechanistic and pharmacokineticldynamic data.
Effects of long term malnutrition The effects of long term malnutrition are more severe in children. Children do not have sufficient amounts of carbohydrates and fats in
The luria-nebraska neuropsychological battery This procedure was first reported in 1978 in the form of two initial validity studies. Historically, Chirstensen, a student of the
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