Risk analysis - in-vitro studies, Biology

Assignment Help:

In-vitro studies

Mechanistic  data might be  supplemented by  data  from in-vitro  studies, like  as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though,  data  from in-vitro studies should not  be  used  as  the  sole source of information to predict the human risk.

-  The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics.  Though, such information may not be available in many cases and  the  risk assessment process should  not  be delayed pending development of mechanistic and pharmacokineticldynamic data.

 


Related Discussions:- Risk analysis - in-vitro studies

Explain early diastolic sound in diastolic, Explain Early Diastolic Sound i...

Explain Early Diastolic Sound in diastolic ? a) Opening snap (0s) of Rheumatic MS: High frequency sound. Generation of sound: Because of high LA pressure, the superior systolic

What best describes the amoebas division, What best describes the amoebas d...

What best describes the amoebas division?  (1) It is a Mode of asexual account in which a one parent is involved. The amoeba cell, which is unicellular, separates into two daug

What is hdls, HDLs have the opposite function to that of LDLs in which they...

HDLs have the opposite function to that of LDLs in which they deleted cholesterol from the tissues.  The HDLs are synthesized in the blood mainly from components derived from the d

Evolution of dental implants, The first evidence of implants dates back to ...

The first evidence of implants dates back to 600 A.D. in the Mayan population. There are reports that the ancient Egyptians attempted intra-osseous implantation of animal teeth or

Explain nutrient needs and recommended dietary allowances, Explain Nutrient...

Explain Nutrient needs and Recommended Dietary Allowances? For infants and preschoolers, satisfactory growth is a sensitive criterion of whether needs are met. 50 th percentil

How is opening and closing of stomata controlled, How is opening and closin...

How is opening and closing of stomata controlled? Describe a) Why is the length of a food chain in an ecosystem generally limited to 3 - 4 trophic levels? Explain with an examp

What is the reason of post endodontic disease, What is the reason of post e...

What is the reason of post endodontic disease ? Either there is persistent or reintroduce intracanal microorganisms.. that means if I do improper instrumentation, improper clea

Explain counseling strategies, Counseling Strategies The counseling str...

Counseling Strategies The counseling strategies which may serve  lo be useful are described herewith. Individual Counseling: Individual counseling is personal counseling.  T

Where is the patient most likely to experience, The most recent blood work ...

The most recent blood work of a patient with a diagnosis of acute myelogenous leukemia (AML) reveals thrombocytopenia. Where is the patient most likely to experience abnormal bleed

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd