Risk analysis - in-vitro studies, Biology

Assignment Help:

In-vitro studies

Mechanistic  data might be  supplemented by  data  from in-vitro  studies, like  as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though,  data  from in-vitro studies should not  be  used  as  the  sole source of information to predict the human risk.

-  The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics.  Though, such information may not be available in many cases and  the  risk assessment process should  not  be delayed pending development of mechanistic and pharmacokineticldynamic data.

 


Related Discussions:- Risk analysis - in-vitro studies

Explain adverse effects of bronchospasm, Adverse Effects of Bronchospasm ...

Adverse Effects of Bronchospasm Nasal and throat discomfort can occur. Bronchospasm, sometimes severe, has been reported uncommonly in patients with reactive airway disease; za

Is diabetes causes the cardiovascular disease, Q. Is Diabetes causes the ca...

Q. Is Diabetes causes the cardiovascular disease? Diabetes: Sustained hyperglycemia is associated with tissue damage and cardio- myopathies. You shall study about diabetes and

Mitochondria , MITOCHONDRIA It is the power house of the cell becaus...

MITOCHONDRIA It is the power house of the cell because they are the major centers of release of energy in the aerobic respiration. Mitochondria and chloroplast both are a

Benefits of hand washing, Benefits of Hand washing You wash hands as a ...

Benefits of Hand washing You wash hands as a routine in daily life before cooking and eating food, after using wash room/toilet, before touching and caring a new born baby, aft

What is enteral feeding, Tube or Enteral Feeding Ideally the patient mu...

Tube or Enteral Feeding Ideally the patient must be fed orally, but in cases where the patient is unable to take solid foods, a part or all of intake is usually given by the tu

Human reproduction, Why is the human placenta referred to as haemochorial t...

Why is the human placenta referred to as haemochorial type? Name the hormone it secretes to facilitate parturition.

Disorders of pancreas, DISORDER S OF THE PANCREAS - (i ) Diabetes me...

DISORDER S OF THE PANCREAS - (i ) Diabetes mellitus (Hypoinsulinism) The insulin-dependent diabetes mellitus (IDDM) is caused by a failure of the Beta-cells to produc

Reproductive system of asteroidea, Reproductive System of Asteroidea S...

Reproductive System of Asteroidea Sexes are separate in several asteroids. There are ten (10) gonads, two in each arm. They emerge tuft-like or as cluster of grapes. Mature go

Explain major divisions of the hypophysis, Q. What are the major divisions ...

Q. What are the major divisions of the hypophysis? What are their functions? The hypophysis is divided into two portions- the anterior hypophysis or adenohypophysis and the pos

Plot the amount of dna in the nucleus, Plot the amount of DNA in the nucleu...

Plot the amount of DNA in the nucleus of spermatogonia from the G1 stage prior to the first meiotic division through the completion of meiosis. Label each of the major stages of th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd