Risk analysis - in-vitro studies, Biology

Assignment Help:

In-vitro studies

Mechanistic  data might be  supplemented by  data  from in-vitro  studies, like  as information on genotoxicity derived from reversion assays or other same assays. These studies should be conducted following GLP and other widely accepted protocols. Though,  data  from in-vitro studies should not  be  used  as  the  sole source of information to predict the human risk.

-  The results of in-vitro studies can enhance the understanding of mechanisms and phannacokinetics/dynamics.  Though, such information may not be available in many cases and  the  risk assessment process should  not  be delayed pending development of mechanistic and pharmacokineticldynamic data.

 


Related Discussions:- Risk analysis - in-vitro studies

Defects in human development, Defects in Human Development 1) For inst...

Defects in Human Development 1) For instance, when a pregnant woman drinks alcohol her embryo is exposed to similar concentration of alcohol as is in her blood. The alcohol ma

Electron transport inhibitors, Electron Transport Inhibitors Several  c...

Electron Transport Inhibitors Several  compounds, including specific drugs, chemicals  and antibiotics  have been known to inhibit the electron  transfer  reactions at specific

Complications during rheumatic heart disease, Q. Complications during rheum...

Q. Complications during rheumatic heart disease? Inflammation of Inning of heart (pericarditis), anaemia, heart ,enlargement, valve deformities (mitral and tricuspid valves),

Concentration Gradients and Membrane Permeability, 3. Which substance(s) cr...

3. Which substance(s) crossed the dialysis membrane? Support your response with data-based evidence.

Explain about the importance of vitamins, Explain about the Importance of V...

Explain about the Importance of Vitamins? Vitamins are the organic substances that act as coenzyme and/or regulator of metabolic processes. There are 13 known vitamins, most of

Discuss briefly the color reactions of proteins, Question 1 List various m...

Question 1 List various methods used for determination of blood glucose. Explain the principle of each test. Add a note on advantages and disadvantages of each method Question

What is the vascular cambium, What is the vascular cambium? What is its fun...

What is the vascular cambium? What is its function? Vascular cambium is the secondary meristematic tissue that in roots and in the stem creates the vascular tissues (xylem and

What is the significance of torsion, What is the significance of torsion? ...

What is the significance of torsion? An unusual twisting of the gastropod body which has left all members of class with an asymmetric body plan and a U-shaped alimentary tract,

Explain about nutritional recommendations for healthy ageing, Explain about...

Explain about the Nutritional recommendations for Healthy Ageing? You would recall reading about meal planning during various stages of life, spanning right from the infancy ti

What are flagella and cilia, Q. What are flagella and cilia and how do thes...

Q. What are flagella and cilia and how do these structures acquire movement? What are some examples of flagellated and ciliated cells in humans? Flagella and Cilia are structur

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd