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Biological effects: Aflatoxins are acute hepatotoxins and are known to be carcinogenic in some animal species as rat. Aflatoxin B1 is acutely toxic and is responsible for liver necrosis. The toxicological effects of the aflatoxins are influenced by their metabolism after intake into their body.
Figure: Representation of the metabolism of aflatoxin and its biological effects
When cows eat feed containing aflatoxin, aflatoxin M1 and M2 is excreted in the milk. Although M1 and M2 are less toxic than the parent compound B1, M1 retains its toxic and carcinogenic ability in many animals. The LD50 of AFB1 for rats by the oral route is 1.2mg/kg and 1.5 to 2.0 mg/kg for AFG1.
explain polymorphism in lysosomes
Define features of Fusarium - Identification of Fungi and Yeasts? Identifying features of Fusarium: 1. Wooly, white fuzzy colonies changing colour to pink, purple or yellow.
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A true-breeding petunia plant with red petals was crossed with another true-breeding petunia plant with white petals. The plants of the F1 progeny had blue petals. When these F1 pl
In an experiment, it was necessary that you determine the concentration of dsDNA by using a spectrophotometer. You used 6 microliters of your purified dsDNA, and the reading at OD=
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a) What are the two types of chemical compound which combine to form a lipid? b) What elements are present in a lipid? a) Lipids are formed from the combination of
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Name three useful products that can be obtained by genetic engineering. Useful products of genetic engineering are:- A) chymosin, B) Alpha-anti-trypsin, C) hepatitis
The sequence for the Beta Actin gene (ACTB) is given below. Which pair of primers (designed to amplify the entire sequence below) could be used to successfully produce the beta act
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