Regulation of cholesterol biosynthesis, Biology

Assignment Help:

Cholesterol can be gained either from the diet or it can be synthesized de novo, mainly in the liver. Cholesterol is transported round the body in lipoprotein particles. The rate of synthesis of cholesterol is dependent on the cellular level of cholesterol. The High levels of cholesterol and its metabolites control cholesterol biosynthesis by:

-  Opinion-inhibiting the activity of HMG CoA reductase an enzyme that catalyzes the committed step in cholesterol biosynthesis;

-  Decreasing the amount of HMG CoA reductase by reducing the synthesis and translation of its mRNA;

-  Decreasing the amount of HMG CoA reductase by raising its rate of degradation.

 

 


Related Discussions:- Regulation of cholesterol biosynthesis

How nutritional status affects the bmr, How Nutritional status affects the ...

How Nutritional status affects the BMR? Under nutrition and starvation are the factors which require consideration. Prolonged under nutrition or starvation causes a reduction o

Define about the eukaryotic cell, The eukaryotic cell The eukaryotic ce...

The eukaryotic cell The eukaryotic cell is a complex unit and contains many structural features not seen in in the simple prokaryotic cell. Fig below shows the details of vario

What do you understand by the term controlled vocabulary, Question 1: E...

Question 1: Enlist the applications of programming and encoding in Pharmaceutical industries Explanation on what is programming and encoding in Pharmaceutical industries

Oxidation reduction potential, what exactly is oxidation and reduction pote...

what exactly is oxidation and reduction potential and how its an imp. factor in spoiling meat

Explain asteroid impacts, Asteroid impacts: The hypothesis which links cer...

Asteroid impacts: The hypothesis which links certain mass extinction events with the impact of the comet or asteroid, most particularly the mass extinction 65 million years which

Identical karyotypes and identical genomes, Q. Can two normal individuals o...

Q. Can two normal individuals of the same species with sexual reproduction have identical karyotypes and identical genomes? And how is the human karyotype usually represented?

Define absorption of zinc - micro minerals, Define Absorption of Zinc - Mic...

Define Absorption of Zinc - Micro Minerals? Like iron, zinc also needs to be liberated from food prior to absorption. During digestive process; proteases, nucleases and hydroch

Regulation of respiration, Regulation of Respiration Whenever the need...

Regulation of Respiration Whenever the need for oxygen in the body increases, ventilation of the respiratory organs also increases. In the same way whenever the level of oxyge

Ecology, Analyse the model that highlights the factors which influence the ...

Analyse the model that highlights the factors which influence the environmental impact of a population

Explain about cmc information about drug substance, Question 1: Describ...

Question 1: Describe upon CMC information about drug substance to be submitted to IND for Phase 3 studies. Definition of CMC Explain about CMC information about drug subs

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd