Regulation of cholesterol biosynthesis, Biology

Assignment Help:

Cholesterol can be gained either from the diet or it can be synthesized de novo, mainly in the liver. Cholesterol is transported round the body in lipoprotein particles. The rate of synthesis of cholesterol is dependent on the cellular level of cholesterol. The High levels of cholesterol and its metabolites control cholesterol biosynthesis by:

-  Opinion-inhibiting the activity of HMG CoA reductase an enzyme that catalyzes the committed step in cholesterol biosynthesis;

-  Decreasing the amount of HMG CoA reductase by reducing the synthesis and translation of its mRNA;

-  Decreasing the amount of HMG CoA reductase by raising its rate of degradation.

 

 


Related Discussions:- Regulation of cholesterol biosynthesis

Explain cardiopulmonary resuscitation, Explain Cardiopulmonary Resuscitatio...

Explain Cardiopulmonary Resuscitation? The heart rhythm associated with cardiac arrest can be either ventricular fibrillation/ ventricular tachycardia (VT/VF) or other rhythms

List the exact sizes of the fragments of digests, (1)  The 7,893 bp plasmid...

(1)  The 7,893 bp plasmid shown below was digested with a series of restriction enzymes (P = PstI, B = BamHI, S = SalI, X = XbaI). Answer the questions below.  a) Indicate

Phosphorus - mineral elements, PHOSPHORUS It is present in vegetables, ...

PHOSPHORUS It is present in vegetables, grains (oat metal, wheat meal), milk, eggs, cheese, meat, fish, etc. It helps in - (a) Like calcium it is a constituent of bones.

Symptoms of botulism, Adult Botulism The symptoms of botulism may deve...

Adult Botulism The symptoms of botulism may develop between 12 and 72 hours after the ingestion of toxin containing foods. Symptoms include nausea, vomiting, fatigue, dizzine

Per -capita rate, In one year, a population size of 500 changed to 496. Wha...

In one year, a population size of 500 changed to 496. What is the per-capita rate of increase/decrease?

Define basic terminology in relation to nutritional needs, Define Basic Ter...

Define Basic Terminology in Relation to Nutritional Requirements? By now you would have a good understanding that nutrient requirements are affected by a number of factors and

Respiration, what is the meaning of direct and indirect respiration

what is the meaning of direct and indirect respiration

Explain what an isotonic fluid loss means, Your client has the flu and repo...

Your client has the flu and reports 5-6 loose stools a day. He has experienced an isotonic fluid volume loss. Explain what an isotonic fluid loss means.

Control of excretion, CONTRO L OF EXCRETION - 1.      In brain hypoth...

CONTRO L OF EXCRETION - 1.      In brain hypothalamus is osmocentre that controls minerals. 2.      Cells of DCT & arterioles combien to form Juxta glomerular node, it se

What is anemia, What is anemia? What are the four main types of anemia? ...

What is anemia? What are the four main types of anemia? Anemia is low concentration of hemoglobin in the blood. The four main types of anemia are the nutrient-deficiency ane

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd