Regulation of cholesterol biosynthesis, Biology

Assignment Help:

Cholesterol can be gained either from the diet or it can be synthesized de novo, mainly in the liver. Cholesterol is transported round the body in lipoprotein particles. The rate of synthesis of cholesterol is dependent on the cellular level of cholesterol. The High levels of cholesterol and its metabolites control cholesterol biosynthesis by:

-  Opinion-inhibiting the activity of HMG CoA reductase an enzyme that catalyzes the committed step in cholesterol biosynthesis;

-  Decreasing the amount of HMG CoA reductase by reducing the synthesis and translation of its mRNA;

-  Decreasing the amount of HMG CoA reductase by raising its rate of degradation.

 

 


Related Discussions:- Regulation of cholesterol biosynthesis

Explain the cyclosporin, Q. What is the cyclosporin? How are fungi related ...

Q. What is the cyclosporin? How are fungi related to this substance? Cyclosporin is a drug discovered in the 1970's that revolutionized organ transplantation in Medicine, It is

What is the magnitude n, Three point charges are located at the corners of ...

Three point charges are located at the corners of an equilateral triangle. Find the magnitude and direction of the net electric force on the 1.60 uC charge. (Let A = 1.60 uC, B= 6.

Of which substance are microtubules made, Of which substance are microtubul...

Of which substance are microtubules made? In which structures and cellular processes do microtubules participate? Microtubules are made of consecutive dimers of the protein tub

What is recombination frequency?, What is recombination frequency? The ...

What is recombination frequency? The Recombination frequency, or crossing over rate, is the percentage of recombinant gametes made by crossing over (in relation to the number o

Disorders of upper respiratory tract, DISORDERS OF UPPER RESPIRATORY TRACT:...

DISORDERS OF UPPER RESPIRATORY TRACT: Common Cold: It is most frequent and most common infection in infants  and children. Common cold corresponds  to  acute nasopharyn

Consequences of diarrhoea, All of us must have suffered from diarrhoea at l...

All of us must have suffered from diarrhoea at least once in our lifetime. How do you feel thereafter? Well most of us must have experienced weakness, dizziness, dryness of mouth a

Diabetes mellitus, 1. How often should she have Glycated hemoglobin (HgbA1C...

1. How often should she have Glycated hemoglobin (HgbA1C) drawn?  What percentage is desired? 2. How often should she see an ophthalmologist or optometrist? 3. What should be

Explain global burden in the history of mart disease, Explain Global burden...

Explain Global burden in the history of mart disease? In 2001, 17 million people died of CVD of all types. The most important causes were ischemic heart disease (IHD), Hyperten

Hydropericardium-hepatitis syndrome, H yd r o p e r i c a r d i...

H yd r o p e r i c a r d i um - h e pa titi s syndrome Also known as 'Angara disease' or 'leachy heart disease', this complex illness of poultry spread rapid

Explain about vascular cambium, How can the age of a tree be estimated from...

How can the age of a tree be estimated from the analysis of the rings present on a cross section of its stem? For the growth of the tree it is essential to have formation of ne

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd