Regulation of cholesterol biosynthesis, Biology

Assignment Help:

Cholesterol can be gained either from the diet or it can be synthesized de novo, mainly in the liver. Cholesterol is transported round the body in lipoprotein particles. The rate of synthesis of cholesterol is dependent on the cellular level of cholesterol. The High levels of cholesterol and its metabolites control cholesterol biosynthesis by:

-  Opinion-inhibiting the activity of HMG CoA reductase an enzyme that catalyzes the committed step in cholesterol biosynthesis;

-  Decreasing the amount of HMG CoA reductase by reducing the synthesis and translation of its mRNA;

-  Decreasing the amount of HMG CoA reductase by raising its rate of degradation.

 

 


Related Discussions:- Regulation of cholesterol biosynthesis

Cytoplasmic matrix, Cytoplasmic Matrix ( = cytosol  or Hyaloplasm ) Thi...

Cytoplasmic Matrix ( = cytosol  or Hyaloplasm ) This is the actual protoplasmic  part of the cytoplasm, containing dissolved proteins, electrolytes, glucose, etc. And forming

Explain glucocorticoids, Explain Glucocorticoids The adrenal cortex se...

Explain Glucocorticoids The adrenal cortex secretes the glucocorticoids which  increase gluconeogenesis by increasing hepatic intake of amino acids accompanied by increased ac

What is rate of photosynthesis in c3 plants, What would happen to the rate ...

What would happen to the rate of photosynthesis in C3 plants if the CO2 concentration level almost doubles from its present level in the atmosphere?

Some precautionary measures to avoid addiction, SOME PRECAUTIONARY MEASURES...

SOME PRECAUTIONARY MEASURES TO AVOID ADDICTION - DEADDICTIO N - First phase of treatment is detoxification. Next phase is of psychotherapy and counselling. Deadi

Factor influencing lipid oxidation - temperature, Factors affecting lipid o...

Factors affecting lipid oxidation Temperature In general, the rate of oxidation increases as the temperature is increased. Temperature also influences the relation betw

Explain entecavir, Explain Entecavir  Entecavir  (Baraclude) taken ora...

Explain Entecavir  Entecavir  (Baraclude) taken orally once a day as monotherapy appears to be superior to lamivudine for patients with chronic HBV infection, but susceptibili

Dna replication in bacteria, The DNA replication is a biological procedure ...

The DNA replication is a biological procedure which happens in all living organisms and copies their DNA; it is the basis for biological inheritance. The process will starts when o

Why iron is required as a part of haemoglobin, Why Iron is required as a pa...

Why Iron is required as a part of haemoglobin? As a part of haemoglobin, iron is required for the transport of oxygen, to all cells in the body. Thus, haemoglobin is critical f

Meiosis, How do meiosis do in developing of new varieties of crops

How do meiosis do in developing of new varieties of crops

How are ecological interactions classified, Q. How are ecological interacti...

Q. How are ecological interactions classified? Ecological interactions are classified as interspecific or intraspecific interactions and as harmonious or inharmonious interacti

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd