Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Peak flow velocity, Peak Flow Velocity  fs  derived  from Doppler  shift by...

Peak Flow Velocity  fs  derived  from Doppler  shift by  rearranging Doppler equation: V = C/2 x ΔF/Fo Various  information can be obtained from spectral display

Health hazards with poor management of bio-medical waste, Health Hazards wi...

Health Hazards with poor management of Bio-medical waste Health hazards associated with poor management of Bio-medical waste are: - Injury from sharps to staff and waste han

Sex differentiation mechanism, SE X DIFFERENTIATION MECHANISM - Pri...

SE X DIFFERENTIATION MECHANISM - Primitive gonads are identical in both sexes upto 6 weeks of gestation pressure. This gonad is known as bipotential primordial gonad. It

What is the drug permeability across the cornea, What is the drug permeabil...

What is the drug permeability across the cornea? Drug permeability across the cornea depends onto: a. Lipid and water solubility of the drug b. Molecular size, weight and

Name the important food hydrocolloids, Some of the important food hydrocoll...

Some of the important food hydrocolloids are listed below: Alginate Carboxymethyl Cellulose Guar gum Gum Arabic Xanthan Gum Carrageenan All h

Explain difference between an ecological niche and a habitat, What is the d...

What is the difference between an ecological niche and a habitat? An ecological place is a set of peculiar activities, resources and strategies that a species explores to repro

Define about iodine metabolism, Define about Iodine Metabolism? Now, we...

Define about Iodine Metabolism? Now, we will very briefly study how iodine is absorbed, distributed in the body and ' excreted out. Like other nutrients, dietary iodide is eith

Ammonotelism - excretion, Normal 0 false false false EN...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What is the significance of elastic capsule chromatophore, What is the sign...

What is the significance of Elastic capsule chromatophore? Specialized pigmented cells on surface of the cephalopods that, by changing their shape, expose differing amounts of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd