Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Expression, To "express" a gene is to make it to function properly. A gene ...

To "express" a gene is to make it to function properly. A gene which encodes a protein will, when expressed, be transcribed or translated to produce that particular protein. A gene

Explain about the protein isolates, Explain about the Protein Isolates? ...

Explain about the Protein Isolates? Before we begin our discussion on protein isolates, let us first get to know how protein concentrates differ from isolates. Basically, the t

What is the choice of a prophylactic agent, Choice of a prophylactic agent ...

Choice of a prophylactic agent An effective prophylactic regimen should be directed against the most likely infecting organisms, but need not eradicate every potential pathogen

Explain the dietary fibre and colon cancer, Explain the Dietary fibre and c...

Explain the Dietary fibre and colon cancer? The relationship between colorectal cancer and dietary fibre remains complex. Although a cause-and-effect relationship between fibre

Explain the enriched and living culture media, Explain the Enriched and Liv...

Explain the Enriched and Living Culture Media? Enriched Media - It is used for isolation of fastidious organisms, i.e., organisms having specific and elaborate nutritional requ

Which foods are used by microorganisms for energy, Q. Which Foods are used ...

Q. Which Foods are used by Microorganisms for Energy? The carbohydrates, especially the sugars, are most commonly used as an energy source, but other carbon compounds can also

Explain mitosis properly, Q. Does the mitosis properly occur after or befor...

Q. Does the mitosis properly occur after or before the interphase? Is it a simple "point of view" issue? Mitosis have to be considered a succeeding phase after interphase since

What do you understand by larval amplification, What do you understand by L...

What do you understand by Larval amplification? A form of asexual reproduction where, during life cycle, a single larval organism can produce large numbers of the next developm

Self - medication, SELF - MEDICATION - Self medication refers to the us...

SELF - MEDICATION - Self medication refers to the use of medicines without consulting a physician. Self medication may be harmful, rather dangerous. It must be avoided. (i)

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd