Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Techniques of plant tissue culture, Techniques of Plant Tissue Culture ...

Techniques of Plant Tissue Culture A standard tissue culture laboratory should provide facilities for washing and storage of glass ware, preparation and storage of nutrient

What are the complementary base-pairing rules for biology, What are the com...

What are the complementary base-pairing rules for biology? In DNA, Adenine bonds with Thymine, Cytosine bonds with Guanine. In RNA, Thymine is changed with Uracil (bases capita

Explain isolated chloroplast thylakoids, In an experiment, isolated chlorop...

In an experiment, isolated chloroplast thylakoids were incubated at pH 4.0 with ADP and inorganic phosphate (Pi) added to the medium and then transferred to a medium having pH 8.0.

Products that can be recycled, It requires the existence of a reliable mark...

It requires the existence of a reliable market for the recovered materials. Although the recovery of certain materials such as aluminium cans large plastic bottles can be profitabl

What is protein targeting, The Protein targeting or protein sorting is the ...

The Protein targeting or protein sorting is the mechanism by that a cell transports proteins to the appropriate positions in the cell or outside of it. A Sorting targets can be the

Processing methods for amelioration of anti-nutritional , Processing Method...

Processing Methods for Amelioration of Anti-Nutritional Meals from many oil seeds often contain undesirable toxic and allergenic compounds that can reduce their nutritive valu

Vascular cambium, Vascular Cambium The vascular cambium usually, if no...

Vascular Cambium The vascular cambium usually, if not always, has a dual origin within the primary tissues; from provascular strands, and from the "ground" meristem tissues be

Animal husbandry-source of energy and protein, Source of Energy and Protein...

Source of Energy and Protein The by-products obtained from grain processing (brans), oil seed processing (oil meals) and pulses processing industries are the major and importan

Conditions requiring rapid treatment of hypertension, List of Conditions Re...

List of Conditions Requiring Rapid Treatment of Hypertension 1) Cardiac: • Acute aortic dissection • Acute left ventricular failure • Acute or evolving myocardial i

How d-glucose differs from d-galactose, D-glucose differs from D-galactose ...

D-glucose differs from D-galactose only in the arrangement around carbon 4. Therefore D-glucose and D-galactose are- Select one: a. enantiomers b. epimers c. mirror ima

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd