Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Respiration in cockroach, what is the chemical reaction of respiration in c...

what is the chemical reaction of respiration in cockroach?

How the visual images are projected, Since the visual images are projected ...

Since the visual images are projected in an inverted manner on the retina why don't we see things upside down? As the crystalline lens is a convex spherical lens it forms inver

Explain false positive tests, Q. Explain False Positive Tests? As ST de...

Q. Explain False Positive Tests? As ST depression has been equated with CAD, patients with this finding who have less than a critical coronary narrowing has been called false p

Theskin, drawandlabelthemajorendocrineglandsofthehumanbody

drawandlabelthemajorendocrineglandsofthehumanbody

Explain deteriorative changes in fats and oils, Explain Deteriorative chang...

Explain Deteriorative changes in fats and oils The food products undergo changes in flavour due to the chemical changes occurring in fats and oils present in them. The causativ

Measurement of functional property of fats and oil, Measurement of Function...

Measurement of Functional Property of fats and oil Fats and oils have several functional properties that affect the quality of processed foods. In deep fat frying, the roles p

What possible combinations of chromosomes will be present, A diploid cell c...

A diploid cell contains three pairs of homologous chromosomes designated C1 and C2, M1 and M2, and S1 and S2; no crossing over occurs. What possible combinations of chromosomes

Protozoa, advantages and disadvantages of protozoa

advantages and disadvantages of protozoa

Describe class aves in details, Describe Class Aves in details? Class ...

Describe Class Aves in details? Class Aves: The fossil record contains evidence that birds evolved from the reptiles. Birds share anatomical features with Protoavis and Archa

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd