Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Food texture and gas formers, Q. Food texture and Gas formers? Food tex...

Q. Food texture and Gas formers? Food texture: Recent studies indicate that strict omission of fibre is of no help on a peptic ulcer patient. The recurrence of peptic ulcer was

When staphylococcal occur, Staphylococci exist in air, dust, sewage, water,...

Staphylococci exist in air, dust, sewage, water, milk and food or on food equipment, environmental surfaces, humans and animals. Humans and animals are the primary reservoirs. Stap

Vein grafts-longevity of conduits long term conduits, Vein Grafts :  ...

Vein Grafts :  At the end of ten years only 50 per cent of saphenous vein grafts are paten1 and 50 per cent of the rest may have significant atherosclerotic changes. In a

How are arthropods characterized, Q Concerning germ layers and the presence...

Q Concerning germ layers and the presence of coelom how are arthropods characterized? Arthropods are triploblastic and coelomate beings (they have three germ layers). Q. Co

Structure and fate of endosperm, Structure and Fate of Endosperm The ...

Structure and Fate of Endosperm The cells of endosperm are usually thin-walled, large isodiametric and devoid of pits and store large amount of food materials. The starch alo

Of which substance are microtubules made, Of which substance are microtubul...

Of which substance are microtubules made? In which structures and cellular processes do microtubules participate? Microtubules are made of consecutive dimers of the protein tub

Explain about the glycemic index (gi), Explain about the Glycemic Index (GI...

Explain about the Glycemic Index (GI)? In the previous sections, we have studied that some carbohydrates are rapidly digested and absorbed, some are digested slowly while some

What is the difference between plasma membrane and cell wall, What is the d...

What is the difference between plasma membrane and cell wall? Plasma membrane and cell wall is not the similar thing. Plasma membrane, also called cell membrane, is the outer m

Safety, S a f e ty, ethical and welfare considerations Development ...

S a f e ty, ethical and welfare considerations Development of transgenic organisms is proceeding in an environment of intense public debate about safety, environmental impa

State long-term benefits of exercise, State four long-term benefits of exer...

State four long-term benefits of exercise. The long-term advantages of exercise are: a) Enhance in size of the muscles used, b) Decrease of heart rate and c)  Enhance

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd