Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Human respiratory system - nasal chamber, NASA L CHAMBER - External...

NASA L CHAMBER - External nares are 2 in number, i.e., dirhynous. Situated at lower side of nose. Open into nasal chamber. Nasal chamber opens into pharynx by internal n

Explain nutritional support management for radiation therapy, Explain Nutri...

Explain Nutritional Support Management for radiation therapy? For managing these patients on radiation therapy, the following measures can be under taken: 1. Administration

Which compounds results from cyclization of glucose, Which of the following...

Which of the following compounds results from cyclization of glucose? Select one: a. alpha-D-glucopyronose b. beta-D-glucopyronose c. alpha-D-glucofuranose d. beta-D

What are cytokines, What are Cytokines? Cytokines are polypeptides, whi...

What are Cytokines? Cytokines are polypeptides, which influence the proliferation, differentiation, metabolism and activation of cells. There are three areas in cancer that hav

Agriculture, what''s a mature female sheep called

what''s a mature female sheep called

Explain the uses of isp in meat products, Explain the Uses of ISP in meat p...

Explain the Uses of ISP in meat products Meat products  The main application of ISP in connection with meat and related products is based on the use of texturized ISP, in

How many hours will the bag last, Mr. Jones I.V. was hung at noon. It is a ...

Mr. Jones I.V. was hung at noon. It is a liter bag and is infusing at 65 ml/hr. How many hours will this bag last?

What are the uses of whey protein concentrates, What are the uses of whey p...

What are the uses of whey protein concentrates? Whey protein concentrates are used extensively in the manufacture of baked goods, where they increase the effectiveness of short

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd