Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Cnidaria - protozoa, Cnidaria - Protozoa The mature medusoid jellyfish...

Cnidaria - Protozoa The mature medusoid jellyfishes like Aurelia are the sexual stages. Sperms and eggs produced in the dissimilar (male and female) individuals ale released i

Explain the systemic metabolic responses, Explain the Systemic Metabolic Re...

Explain the Systemic Metabolic Responses? Many of the metabolic responses to infection are similar to those following injury. The key changes include: Hyper metabolism: Oxyg

Objection, i have question that all scientist agree that the basic unit off...

i have question that all scientist agree that the basic unit off life is a cell and scientist said this to be a cell theory... and they also said that if a theory survive continuou

Photosynthesis., what carbohydrates does a plant make from glucose

what carbohydrates does a plant make from glucose

Estrus - estrous cycle, Estrus - Estrous cycle This is the period of h...

Estrus - Estrous cycle This is the period of heat, and copulation is permitted only at this time. This condition lasts from 9 to 15 hours and is characterised by a high rate o

State the term - infection, State the term - Infection Infection is th...

State the term - Infection Infection is the invasion of the body by disease-producing (pathogenic) microorganisms and the reaction of the tissues to their presence and to the

Bone remodeling, Bone Remodeling Bone remodeling differs from the other...

Bone Remodeling Bone remodeling differs from the other means of bone structure alteration in that osteoblasts and Osteoclasts do not act independently but are coupled and bone

What are the results of pulmonary artery banding, What are the Results of p...

What are the Results of pulmonary artery banding ? Results of surgery for ventricular septa1 defects are excellent. Though the mortality is not 0 per cent, in a large series it

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd