Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Genetic code be qualified as a "degenerate code", Q. Why can the genetic co...

Q. Why can the genetic code be qualified as a "degenerate code"? The genetic code is a degenerate code because there are amino acids codified by more than one type of codon, it

What is the plasma membrane of the cell, Q. What is the plasma membrane of ...

Q. What is the plasma membrane of the cell? What are its major functions? The plasma membrane is the external membrane of the cell, it delimits the cell itself and a cell inter

Class of crustacea - cirripedia, Class of Crustacea - Cirripedia These...

Class of Crustacea - Cirripedia These crustaceans are completely marine, and include the barnacles. Moa species are free living, attached to rock, and other objects. Some are

Haemodynamics of tricuspid regurgitation, Q. Haemodynamics of Tricuspid reg...

Q. Haemodynamics of Tricuspid regurgitation? Right Atrial pressure tracing shows a prominent ‘v' wave and these cannot be appreciated in a patient with atrial fibrillation. RV

How white blood cells are collectively referred, The various types of white...

The various types of white blood cells are sometime together referred to as: a) Erythrocytes (pron: eh-rith-row-cites) b) Erythroblasts (pron: eh-rith-rah-blast) c) Leuko

Which of substance are microfilaments, Q. Which Of substance are microfilam...

Q. Which Of substance are microfilaments made and what are the properties of these elements that give motility to cells? Microfilaments are made of actin a protein. The contrac

Respiration, Can you define respiration in 5 oganisms

Can you define respiration in 5 oganisms

Protozoa, what are characteristics of flagellata class ?

what are characteristics of flagellata class ?

Explain about the phosphorus - macro minerals, Explain about the Phosphorus...

Explain about the Phosphorus - Macro Minerals? Phosphorus is the second most abundant element in the human body, comprising 30% of the total mineral content. An adult human bod

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd