Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

Is glucose can be oxidized to two primary products, In the RBC, glucose can...

In the RBC, glucose can be oxidized to two primary products. One of the oxidation proucts is ribulose 5 phosphate, and the other is which of the following compounds? -lactate

What is the life cycle of the schistosome, What is the life cycle of the sc...

What is the life cycle of the schistosome? Male and female adult schistosomes live in blood vessels of the human intestines. The females release eggs that trespass the vessel w

Respiration in animal, what is respiration in animals ,its functions ,types...

what is respiration in animals ,its functions ,types of respiration

Explain characteristics that make breastfeeding beneficial, Explain charact...

Explain characteristics that make breastfeeding beneficial to the infant? We have listed some characteristics that make breastfeeding beneficial to the infant: • Mature milk

Porifera, Diagrams of organisms in phylum porifera

Diagrams of organisms in phylum porifera

.phylum pisces, wt is an air bladder and its function wt is catadromous and...

wt is an air bladder and its function wt is catadromous and anadromus migration

Types of fertilization, TYPES OF FERTILIZATION - On the basis of site o...

TYPES OF FERTILIZATION - On the basis of site of fertilization, it is of two types - 1. External fertilization        2. Internal fertilization 1 .       EXTERNAL FERTILIZ

What are the parts of the female reproductive system, What are the organs t...

What are the organs that are part of the female reproductive system? The organs that comprise the female reproductive system are the ovaries, the Fallopian tubes (or uterine t

Briefly explain how amniocentesis used in genetic screening, Briefly explai...

Briefly explain how amniocentesis and chorionic villi sampling are used in genetic screening. A small sample is removed from the amniotic fluid surrounding the fetus or from t

Why he literally paralyzed the cilia, Your patient has a respiratory diseas...

Your patient has a respiratory disease that has literally paralyzed the cilia. Explain why this patient would be at an increased risk for a respiratory infection.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd