Reduction in left ventricular, Biology

Assignment Help:

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.


Related Discussions:- Reduction in left ventricular

What are halophile, What are halophile, thermoacidophile and methanogen arc...

What are halophile, thermoacidophile and methanogen archaebacteria? There are three peculiar parts of archaebacteria. The halophile archaebacteria only survive in salt-rich env

Explain the resorbable barriers - root perforation, Explain the Resorbable ...

Explain the Resorbable Barriers - Root Perforation It is successfully control internal bleeding through cronal access It is intended to forced in the bone, not left wi

Coordination of digestion, Coordination of Digestion You have learnt ...

Coordination of Digestion You have learnt that digestion is a process in which large food molecules arc broken down step by step into their constituents. In primitive metazoa

Psychoactive plants of the old world, Archaeological data provide valuable ...

Archaeological data provide valuable information about the uses of plants in the past. Information comes from a number of sources, including fossil plant and human remains as well

Explain uses of modified starches in food, Uses of modified starches in foo...

Uses of modified starches in food and confectionery industries Visit a grocery shop and look out for products such as the instant desserts, jelly beans, salad dressings, tomato

Gametes, examples of gametes

examples of gametes

What are the results of chrchronic pulmonary thromboembolism, What are the ...

What are the Results of Chronic Pulmonary Thromboembolism? Results :  The reported mortality is between 5 and 24 per cent. On follow-up, the six-year survival in the best ce

Show the physical criteria of quality for honey, Q. Show the Physical crite...

Q. Show the Physical criteria of quality for Honey? Colour, crystallization, pH, acidity, water content are some of the criteria used for analysis of honey. These criteria are

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd