Radioisotopes, Biology

Assignment Help:

Radioisotopes

Radioisotopes are those forms of an element which exhibit rzdioactivity and so can be used as markers or tracers. For this purpose, we first introduce the radioisotope in a molecule in the cell and then detect the radioactivity with the help of certain device. For example, if we replace a suitable hydrogen atom of thymidine by 3H, we may trace the course of thymidine in the cell. Since thymidine is a component of DNA but not of RNA, we can be sure that we are following only DNA metabolism. Similarly, to know the course of protein synthesis we may use radioactively labelled amino acids.

Radioisotopes are used to:

(a) measure the rates of metabolic turnover of a material within a cell or tissue,

(b) locate the site of synthesis of molecules,

(c) measure the rate of exchange of materials across cellular membranes,

(d) locate a molecule in a cell. Radioisotopes are widely applied to study also the precursor-product relathship.

Many times when a radioactively labelled mokcule (pncursor) is introduced into a system. The molecule is chemically converted into another form (product). For example, when radioactive iron is introduced in blood, radioactivity can be detected in liver femtin and haemoglobin of red blood cells. Similarly, radioactivity of 32P- labelled phosphate can be detected in many phospholipids.


Related Discussions:- Radioisotopes

Explain about metabolic diseases, Q. Explain about Metabolic diseases? ...

Q. Explain about Metabolic diseases? Metabolic diseases, as you already know, refer to those disorders in which the various reactions in the cells are effected (production of e

Restraining, RESTRAINING: Several treatment alternatives exist  for  i...

RESTRAINING: Several treatment alternatives exist  for  intervention in assaultive behaviour. Medication, physical restraints and seclusion  rooms may be used  separately or

Define body mass index (bmi), Define Body Mass Index (BMI)? Weight for ...

Define Body Mass Index (BMI)? Weight for height as a marker of nutritional status has the advantage that it is independent of other factors that affect foetal outcome such as m

Determine the uses of the gums, The use of the gums in various foods may af...

The use of the gums in various foods may affect the following functional properties: 1. Water-binding capacity 2. Rheological properties 3.  Capacity to form film or gel

Hypothesis - nursing research, Hypothesis: The  spelling of hypothesis...

Hypothesis: The  spelling of hypothesis when written  as  "hypotheses"  indicate plural. The hypothesis is a statement or declaration of  the expected outcome of a research st

The best describes calcium metals, Which of the following terms best descri...

Which of the following terms best describes calcium metals? Check all that apply. Molecule, element, matter, and compound.

Which is not produced by the hypothalamus, Which of the following is NOT pr...

Which of the following is NOT produced by the hypothalamus? A) releasing hormones B) inhibiting hormones C) antidiuretic hormone D) oxytocin E) thyroid-stimulating h

Morphological changes - floral induction, Morphological Changes - Floral In...

Morphological Changes - Floral Induction Some of the morphological changes that accompany floral induction are: Change in the shape of meristem, Increase in the ra

How emulsion can stabilized, How emulsion can stabilized Emulsions can ...

How emulsion can stabilized Emulsions can be stabilized by the use of emulsifiers, finely divided particles adsorbed at the interface and water dispersible hydrocolloids. Emuls

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd