Radioisotopes, Biology

Assignment Help:

Radioisotopes

Radioisotopes are those forms of an element which exhibit rzdioactivity and so can be used as markers or tracers. For this purpose, we first introduce the radioisotope in a molecule in the cell and then detect the radioactivity with the help of certain device. For example, if we replace a suitable hydrogen atom of thymidine by 3H, we may trace the course of thymidine in the cell. Since thymidine is a component of DNA but not of RNA, we can be sure that we are following only DNA metabolism. Similarly, to know the course of protein synthesis we may use radioactively labelled amino acids.

Radioisotopes are used to:

(a) measure the rates of metabolic turnover of a material within a cell or tissue,

(b) locate the site of synthesis of molecules,

(c) measure the rate of exchange of materials across cellular membranes,

(d) locate a molecule in a cell. Radioisotopes are widely applied to study also the precursor-product relathship.

Many times when a radioactively labelled mokcule (pncursor) is introduced into a system. The molecule is chemically converted into another form (product). For example, when radioactive iron is introduced in blood, radioactivity can be detected in liver femtin and haemoglobin of red blood cells. Similarly, radioactivity of 32P- labelled phosphate can be detected in many phospholipids.


Related Discussions:- Radioisotopes

Define isolated soybean proteins in seafood products, Define isolated soybe...

Define isolated soybean proteins in Seafood products? The most important application in this category is the use of ISP in fish sausage and surimi based restructured fish produ

Enzymes, what is rennin? how does it work? and what is its optimum pH level...

what is rennin? how does it work? and what is its optimum pH level and activity temperature?

Explain the term direct calorimetry, Explain the term Direct Calorimetry? ...

Explain the term Direct Calorimetry? Calorimetry refers to the measurement of the amount of heat evolved or absorbed in a chemical reaction, change of state, or formation of a

Hyperlipidemia, Dyslipidemia is an important correctable factor for Coronar...

Dyslipidemia is an important correctable factor for Coronary Artery Disease. There is a strong, independent, continuous, and graded relation between total cholesterol (TC) or low-

Function of lipids, FUNCTIO N OF LIPIDS Fats are storage products ...

FUNCTIO N OF LIPIDS Fats are storage products of both plants and animals. I n plants , fats are commonly stored in spores and seeds while in animals they are sto

Specific considerations and applied aspects in dentistry, Specific consider...

Specific considerations and applied aspects in dentistry The dental chair and delivery system. The chair should be smooth and seamless. The greatest potential for cross contami

Atypical distribution of pleural fluid, Q. Atypical Distribution of Pleural...

Q. Atypical Distribution of Pleural Fluid? i) Lamellar effusion: These are shallow collections of fluid between the chest wall and the lung surface. ii) Subpulmonic

Define absorption, Define Absorption, Storage and Elimination of Vitamin K?...

Define Absorption, Storage and Elimination of Vitamin K? Dietary vitamin K, mainly phylloquinone, is absorbed chemically unchanged from the proximal intestine after solubilizat

Explain coenzyme a, Coenzyme A Coenzyme A  is  derived  from  the  vita...

Coenzyme A Coenzyme A  is  derived  from  the  vitamin pantothenic  acid. This  is abbreviated  as CoA.  This  can  be  divided into  two  components, adenosine  3,5-diphosphat

Determine the term clade, Determine the term Clade? In cladistic taxono...

Determine the term Clade? In cladistic taxonomy, how groups of animals are related to each other. It includes the ancestral group and all of the other groups, or lineages, of a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd