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Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function. Intended for the latter reason the activity of pyruvate carboxylase depends absolutely on the presence of acetyl CoA; the biotin prosthetic set of the enzyme cannot be carboxylated unless acetyl CoA is bound to the enzyme. This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.
Explain the Expanding Frontiers of Nutrition? While the essential nutrients mentioned in Table are indispensable and our diets need to provide them all in adequate quantities,
Q. What is cerumen? Cerumen is a fatty, oily substance produced by theceruminous glands in outer part of ear canal. This compound is generally referred to as ear wax and, toget
Which of the following serves as a sensor, or as part of a sensor, that functions in a negative feedback system? A. Central thermoreceptor neurons whose peripheral terminals ar
This method makes use of a common, but peculiar, group of DNA sequences known as minisatellites. High levels of variation in the numbers of these repeated units are used in "DNA fi
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