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Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function. Intended for the latter reason the activity of pyruvate carboxylase depends absolutely on the presence of acetyl CoA; the biotin prosthetic set of the enzyme cannot be carboxylated unless acetyl CoA is bound to the enzyme. This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.
Question 1: What is the benefit of alternative splicing? Could there also be drawbacks of Alternative splicing? If yes, mention the same. Definitions of alternative splic
R a d i o g raphic imaging: Radiology has been in use since the discovery of X-rays by Wilhelm Conrad Roentgen in 1895. Until 1980s, radiography was the
What are the disadvantages of protozoa
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What do you mean by Cori Cycling? In this cycle, glucose released by peripheral tissues is metabolized to lactate, which is then resynthesized to glucose in the liver. This pro
Explain about the term- Therapeutic Therapeutic approaches that scientists are pursuing include transplanting cells to replace those which are damaged or using growth factors
Explain about the Ocular Haemodynamics. The pressure in the ocular arteries can be measured by optical ophthalmodynamometer. The intraocular pressure is raised to the level tha
Iron Deficiency Anaemia This is the most common nutritional and haematologic disorder in infancy and chhildhood in developing countries. It is caused by lack of sufficient i
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