Pyruvate carboxylase activation, Biology

Assignment Help:

Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function.  Intended for the latter reason the  activity  of  pyruvate  carboxylase   depends  absolutely  on  the  presence  of acetyl  CoA; the biotin  prosthetic  set  of the enzyme  cannot  be carboxylated unless acetyl  CoA is bound  to the enzyme.  This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.

 


Related Discussions:- Pyruvate carboxylase activation

How does epistasis affect proportion of phenotypical form, In the hybridiza...

In the hybridization of 2 genes (4 different alleles, 2 of each pair) how does epistasis affect the proportion of phenotypical forms in the F2 generation? In the dihybridism wi

What do you mean by tubular secretion, Q. What is tubular secretion? What a...

Q. What is tubular secretion? What are some examples of substances secreted through the renal tubules? Uric acid, Ammonia, potassium bicarbonate and hydrogen ions, bases and me

Why is genetic homozygosity dangerous, Why is genetic homozygosity dangerou...

Why is genetic homozygosity dangerous to a nearly extinct species? Genetic homozygosity leaves no variation for natural selection to act on. Thus, a new disease could wipe

Cholesterol, CHOLESTEROL Other name is parental steroid. It is ...

CHOLESTEROL Other name is parental steroid. It is present all over the body but absent in cerebrospinal fluid. Cholesterol is found exclusively in animal food. It

Explain the protection of erythrocytes and cell membrane, Explain the Prote...

Explain the Protection of erythrocytes and cell membrane? Protection of erythrocytes: Vitamin E protects erythrocytes from haemolysis by the production of oxidizing agents

Solubility, Solubility You are aware that gases are soluble in liquid...

Solubility You are aware that gases are soluble in liquid. Solubility of a gas in a liquid depends on the partial pressure, temperature and presence of other solutes. Table

Nicotinic acid or niacin, Niacin affects all lipid parameters favorably. It...

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of freq

Define briefly the enzymatic proteins, Define Briefly the Enzymatic Protein...

Define Briefly the Enzymatic Proteins? The most varied and very highly specialized proteins are those along with catalytic activity - the enzymes. Virtually all the chemical re

What is trophic levels and food webs, What is Trophic Levels and Food Webs?...

What is Trophic Levels and Food Webs? Trophic Levels and Food Webs : Energy flows and nutrients are cycled through an ecosystem via organisms that feed on one another. When c

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd