Proximal convoluted, Biology

Assignment Help:

Proximal Convoluted

Tubule The glomerular filtrate, which is isosmotic to plasma, enters the proximal convoluted tubule where its volume is reduced by about 80%. This reduction in fluid v6lume is 'accomplished by the active reabsorption of NaCl, glucose, amino acids, etc. from the tubular fluid. As these solutes are removed, the tubular fluid becomes hypoosmotic and the interstitial fluid surrounding the tubular wall becomes hyperosmotic. This causes passive diffusion of water out of the tubule to restore isosmotic condition between the tubular fluid and the surrounding cortical interstitium.

This reabsorption of water is secondary to solute transport and occurs inevitably irrespective of the water requirements of the body. Hence, it is called the obligatory reabsorption of water. Thus, in the proximal convoluted tubule, there is a drastic reduction in fluid volume without any change in its osmolarity. At the normal plasma glucose concentration of 100 mg per 100 ml, glucose is totally reabsorbed from the ultrafiltrate in the proximal convoluted tubule. If the plasma glucose concentration increases above the .normal level, its concentration in the ultrafiltrate also increases correspondingly. If it exceeds, the capacity of the transport mechanism to reabsorb, some glucose appears in the urine as happens in diabetic patients.


Related Discussions:- Proximal convoluted

Endoplasmic reticulum (er), Endoplasmic reticulum (ER) is the network of m...

Endoplasmic reticulum (ER) is the network of membranous tubules in the cytoplasm of a cell; involved in production of the phospholipids, proteins, and the other functions. Rough E

Define the term - lateralisation and localisation, Define the term - latera...

Define the term - lateralisation and localisation Discriminative validity studies including lateralisation and localisation achieved satisfactory results, but the localisation

Meal planning and nutrient needs of fast-growing infants, Define meal plann...

Define meal planning and nutrient needs of fast-growing infants? We just got to know the meal planning and nutrient needs of fast-growing infants and preschoolers in the previo

Non-modifiable risk factors for coronaru heart diseases, Q. Non-Modifiable ...

Q. Non-Modifiable Risk Factors for coronaru heart diseases? Non-Modifiable Risk Factors 1. Age 2. Sex 3. Heredity 4. Endomorphic Body Build Family history: Pe

Why is aids difficult to prevent by vaccination, Q. Why is AIDS difficult t...

Q. Why is AIDS difficult to prevent by vaccination? It is not easy to produce a vaccine against AIDS because the HIV is a highly mutant virus. In approximately every replicatio

Prevention and control of water pollution, Various ways/techniques suggeste...

Various ways/techniques suggested for control of water pollution are as follows: 1. Pollutants (radio active, chemical, biological) present in water bodies can be removed by app

Explain the metabolic rate of aerobic organisms, Why can the consumption of...

Why can the consumption of molecular oxygen indicate the metabolic rate of aerobic organisms? Molecular oxygen (O2) consumption has direct relation to the cell metabolic rate i

Define briefly about the conjugated proteins, Define briefly about the Conj...

Define briefly about the Conjugated Proteins? Conjugated proteins are made up of simple proteins combined with a non- proteinous substance. The non-proteinous substance is know

Show the effect of left ventricular hypertrophy, Q. Show the Effect of Left...

Q. Show the Effect of Left Ventricular Hypertrophy? The increase in coronary flow has been termed flow reserve and its magnitude is important in providing adequate perfusion t

Explain acute mr murmur in heart dieases, Explain Acute MR Murmur in heart ...

Explain Acute MR Murmur in heart dieases? MR due to ruptured papillary muscle, ruptured chordae tendinae, or due to Infective Endocarditis/Myocardial infarction. Characteri

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd