Proximal convoluted, Biology

Assignment Help:

Proximal Convoluted

Tubule The glomerular filtrate, which is isosmotic to plasma, enters the proximal convoluted tubule where its volume is reduced by about 80%. This reduction in fluid v6lume is 'accomplished by the active reabsorption of NaCl, glucose, amino acids, etc. from the tubular fluid. As these solutes are removed, the tubular fluid becomes hypoosmotic and the interstitial fluid surrounding the tubular wall becomes hyperosmotic. This causes passive diffusion of water out of the tubule to restore isosmotic condition between the tubular fluid and the surrounding cortical interstitium.

This reabsorption of water is secondary to solute transport and occurs inevitably irrespective of the water requirements of the body. Hence, it is called the obligatory reabsorption of water. Thus, in the proximal convoluted tubule, there is a drastic reduction in fluid volume without any change in its osmolarity. At the normal plasma glucose concentration of 100 mg per 100 ml, glucose is totally reabsorbed from the ultrafiltrate in the proximal convoluted tubule. If the plasma glucose concentration increases above the .normal level, its concentration in the ultrafiltrate also increases correspondingly. If it exceeds, the capacity of the transport mechanism to reabsorb, some glucose appears in the urine as happens in diabetic patients.


Related Discussions:- Proximal convoluted

Explain about chronic gastritis, Q. Explain about Chronic Gastritis? It...

Q. Explain about Chronic Gastritis? It precedes development of organic gastric lesion, or tissue damage. Recurrent inflammation leads to changes in enzyme activity of gastric m

Explain the law of segregation, Explain how the events of meiosis account f...

Explain how the events of meiosis account for the law of segregation and the law of independent assortment. In meiosis, the two alleles of every gene are segregated when the tw

Biochemical methods of detecting tumors, Based on your knowledge of neoplas...

Based on your knowledge of neoplasia, discuss biochemical methods of detecting tumors, and imaging characteristics (in your particular imaging modality) that suggest malignancy. Ex

Myocardial ischemia, In patients with coronary artery disease an acute coro...

In patients with coronary artery disease an acute coronary syndrome event can precipitate heart failure. Mitral regurgitation occurring as a result of papillary muscle ischemia con

Which is an isotope of pgisphorous, The most abundant from of phosphorous h...

The most abundant from of phosphorous has 15 protos, 16 neutrons and 15 electrons. Which of the following is an isotope of pgisphorous? (make all correct choices) A. an atom wit

Movement of body parts, MOVEMENT OF BODY PARTS - Movement of appenda...

MOVEMENT OF BODY PARTS - Movement of appendages bring about locomotion. Perapodia, setae in Annelida, jointed legs in Arthropoda, flat foot in mollusca, tube feat in sta

How establish a pure-breeding population of brown pigs, Would it be possibl...

Would it be possible to establish a pure-breeding population of brown pigs with a few black spots?

Process of determination of vitamin B12, Determination of vitamin B 12 ...

Determination of vitamin B 12 Spectrophotometric determination of the characteristic ultraviolet absorption is suitable for the determination of pure vitamin B 12 or of pure

What is the chemical nature of carbohydrates, What is the chemical nature o...

What is the chemical nature of carbohydrates? The name carbohydrate owes its origin to the fact that most substances of this class have empirical formulae suggesting that they

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd