Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Promotion - Stages of carcinogenesis
The second stage or promotion is reversible and does not include changes in structure of DNA but rather in the expression of the genome of the initiated cell. This results from an interaction among the changed DNA structure and some environmental factors termed 'promoting agents'. The stage of promotion needs extended interaction with the promoting agent, if the third stage of progression is to be teached. Figure describes the process of promotion in a simplified way. A single application of an initiator to the skin of a mouse produces initiated cells but no tumor
Figure: The concept of initiation and promotion
(a) However, if the initiator is applied to the skin first then subsequent application of the promoter results in tumor
(b) If the promoter is withdrawn the tumor regresses leaving behind initiated cells and continued application of promoter on tumor bearing skin lends to invasive carcinoma.
(c) The application of a promoter alone to the skin also does not produce tumor
(d) If the promoter is applied before the initiator is applied even then no tumor is formed.
GIRDLES - (i ) PECTORAL GIRDLE - 4 bones. It is located on posterolateral part of upper region of the throax. It consists of scapula & clavicle. Scapula is placed
Bud Dormancy - Plant Growth Substances Environmental Factors The most important factor inducing dormancy appears to be photoperiod. Short days induce dormancy in many w
The adaptive mechanisms may be short term ones which come into play within minutes or hours of the onset of myocardial dysfunction. These are: Frank-Starling Mechanism In
Peste des petits ruminants (PPR) is an acute, highly contagious viral disease of goats and sheep caused by peste des petits ruminants (PPR) virus which belongs to the genus Morbil
Absence of Passive Fit of the Prosthesis A passive fit of the prosthesis reduces long term stresses in the superstructure, implant components and the bone adjacent to the impla
Explain the factors that led to the decline of Science in Europe during iron age
The technical term used for the androecium in a flower of China rose (Hibiscus rosasinensis) is: 1. Monadelphous 2. Diadelphous 3. Polyandrous 4. Polyadelphous
What group did reproduction via sexual exchange of genetic information originate in?
Explain Keshan disease caused by Selenium deficiency? It is a cardiomyopathy (disease of the myocardium, involving heart muscle) that was identified to affect children and wome
Q. Managing diarrhoea in children? Managing diarrhoea in children is of great concern. The guidelines for the same are as follows: 1. The first objective is to rehydrate the
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd