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Probit analysis is the technique most commonly employed in the bioassay, specifically toxicological experiments where the group of animals is subjected to known levels of a toxin and a model is needed to relate the proportion surviving at the particular dose, to the dose. In this kind of evaluation the probit transformation of a proportion is modeled as a linear function of the dose or more frequently, the logarithm of the dose. Estimates of the parameters in the model are found by the maximum likelihood estimation.
The distribution free or technique which is the analogue of the analysis of variance for the design with two factors. It can be applied to data sets which do not meet the assumptio
Minimization is the method or technique for allocating patients to the treatments in clinical trials which is usually the acceptable alternative to random allocation. The procedur
Auto correlation : The correlation of the internal observations in the time series, generally expressed as a function of the time lag between the observations. It is also used for
McNemar's test is the test for comparing proportions in data involving the paired samples. The test statistic can be given by it is most useful when the data have a symmetri
Non-randomized clinical trial is the clinical trial in which the series of consecutive patients receive a new treatment and those which respond (according to some of the pre-defin
Multi-hit model is the model for a toxic response which results from the random occurrence of one or the more fundamental biological events. A response is supposed to be induced o
Causality: The relating of the reasons to the effects they produce. Several investigations in medicine seek to establish the causal relations between the events, for instance, whi
National lotteries : Games of chance held to heave money for particular causes. The first held in the UK took place in the year 1569 principally to raise money for repair of the Ci
1. The production manager of Koulder Refrigerators must decide how many refrigerators to produce in each of the next four months to meet demand at the lowest overall cost. There i
A metal fabrication process uses a die-cast metal fastener at a uniform rate of 300 units per year. Currently, this item is currently purchased from an external supplier at a unit
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