Prevention of malaria

No drug for malaria prevention is 100% effective. Travelers to countries that have malaria should seek prompt medical attention for febrile illness whereas traveling and after return, especially in the first 2 months. Chloroquine is the drug of choice for prevention of malaria in the few places that still have chloroquine-sensitive malaria: Central America west of the Panama Canal Zone, Paraguay, northern Argentina, Mexico, Haiti, the Dominican Republic and most of the Middle East (chloro- quine resistance has been reported in Iran, Yemen, Oman, and Saudi Arabia). In rural areas of China where malaria occurs, it is generally chloroquine sensitive. Only Hainin and Yunnan provinces have chloroquine resistance.