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The potassium-sparing agents spironolactone, triamterene, and amiloride are often useful in combination with the loop diuretics and thiazides. Triamterene and amiloride act on the distal tubule to reduce potassium secretion. Their diuretic potency is only mild and not adequate for most patients with heart failure, but they may minimize the hypokalemia induced by more potent agents.
Side effects: Hyperkalemia, gastrointestinal symptoms, renal dysfunction and gynecomastia.
Plasma Proteins - Circulation The total protein concentration of the plasma is around 7% only. The plasma proteins are of three types - serum albumin (4%), serum globulin (2.7
Pathophysiology If the ductus arteriosus does not close after birth, the higher pressure in the aorta than in the pulmonary artery causes the blood to flow from the aorta, t
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