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The potassium-sparing agents spironolactone, triamterene, and amiloride are often useful in combination with the loop diuretics and thiazides. Triamterene and amiloride act on the distal tubule to reduce potassium secretion. Their diuretic potency is only mild and not adequate for most patients with heart failure, but they may minimize the hypokalemia induced by more potent agents.
Side effects: Hyperkalemia, gastrointestinal symptoms, renal dysfunction and gynecomastia.
Genetic Defect in Pyruvate Dehydrogenase A defed in any of the protein subunits of PDH can result in decrease or complete loss of activity. Severe cases are usually fatal. Sy
Differentiation of Tissues - Root Apex New cells generated from the divisions of meristematic cells start expanding and differentiating further. Epidermis, cortex and stele a
Chemistry of Living Matter All living things including ourselves, are made of protoplasm. Protoplasm is essentiallya colloidal suspension of proteins in a w&ery solution. It is c
Theor y of Epigenesis (i) It was proposed by C.F. Wolff & supported by Von Baer. (ii) Wolff proposed that germ cells contain definite but undifferentiated
Endothelium - Ovule In plants bearing unitegmic ovules, the nucellus degenerates during early stages of ovule development and the embryo sac comes in contact with the innermos
Another important genus of mycotoxin producers is Fusarium, many species of which produce members of the trichothecene family of mold metabolites like deoxynivalenol, neosolaniol a
Canine distemper Canine distemper, a highly contagious disease of dogs, is caused primarily by air- borne virus which belongs to the genus Morbillivirus in family Paramyxoviri
Thiamine deficiency (hypothiaminosis) Thiamine deficiency is characterized by signs of nervous system. The primary thiamine deficiency is not common in animals. However, seco
Diabetes Mellitus Management after Open Heart Surgery : Diabetic patients undergoing coronary artery bypass surgery who are on oral hypoglycemic drugs are pre operatively s
Induction of Defensive Barriers in Plants Several polymers deposited near surface of plants form an effective barrier against invasion or stress. Cuticle (which consists of a
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