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Integral plasma membrane proteins are also synthesized by ribosomes on the RER, but become inserted in the rough endoplasmic reticulum membrane rather than transported into the lumen. In During transport to the Golgi and then to the cell surface these proteins stay anchored in the membrane, the last vesicles that fuse with the plasma membrane then becoming latest plasma membrane that is given in the below figure. Note that, after insertion
Figure: A simplified version of the signal hypothesis
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What happens when the ovum is fertilized? If the ovum is fertilized, there is no breakdown of endometrium and no menstrual flow. The fertilized ovum travels through uterine tub
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