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PITUITARY DISORDERS -
(a) Pituitary Dwarfism. It is caused by the deficiency of growth hormones (GH) from childhood. It is characterised by small but well porportioned body and sexual immaturity. The dwarfs produced by the deficiency of growth hormone are different from those which are formed from the deficiency of thyroid hormone in having normal intelligence. (b) Gigantism. It is caused by excess of growth hormone from early age. It is characterised by large and well proportioned body. If size of pituitary gland increases, it affects (supresses) optic chiasma and ultimately affects vision.
(c) Acromegaly (Acro- extremity. megaly-Iarge). It is caused by excess of growth hormone after adult size is reached. It is characterised by disproportionate increase in size of bones of face, hands and feet.
(d) Kyphosis - In old age by extra secretion of GH.
(e) Diabetes insipidus. It is caused by the deficiency of ADH. It is characterised by excessive excretion of dilute urine.
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It is IgG mediated cytotoxic hypersensitivity. Typical manifestations contain erythroblastosis fetalis, hemolytic anemia, blood transfusion reactions etc.
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