Physiology of excretion, Biology

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PHYSIOLOGY OF EXCRETION -

1.      FORMATION OF UREA -

It takes place in liver.

(i) Deamination

799_formation of urea.png

(ii) Ornithine cycle or urea cycle -

  • Explained by H. Kreb and Hansleit. 2 mol of NH3, 1 CO2, 2H2O combine to form urea as byproduct.
  • 3 A.T.P. are consumed.
  • Process takes place in five steps -

Enzyme used in five steps are -

1. Carbamyl phosphate synthatase                       

2. Ornithine carbamyl transferase.

3. Argino-succinic acid synthetase                       

4. Argio-succinase                                

5. Arginase

1438_formation of urea1.png


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