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Physiological Changes - Consequences of Aging
Various physiological regulatory mechanisms show decreased efficiency due to aging. For instance, normally the glucose level in the blood shows very little change with age, but if glucose is injected into the blood the rate of restoration to normal level depicts a marked dependence on age: it is far slower in old people as compared to in young. It has been concluded from many physiological studies that the highest change is found in functions that involve the coordinated activity of a number of organ systems. Those that include only a single organ or system show little change kith age.
Whenever a chromosome is replicated the replication machinery passes by the nucleosomes without deleting the histones from the DNA. How this happens is since not fully understood.
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