Permissive interaction - pancreas development, Biology

Assignment Help:

Permissive Interaction - Pancreas Development

Figure describes the development of pancreas in a mammal. In an organism like mouse the pancreas is first seen as a diverticulum of embryonic gut approximately 9th day of development. As the diverticulum grows it pushes into mesenchyme and branches making blind pockets called acini. The cells of these pancreatic acini distinguish into exocrine cells that produce digestive enzymes-the peptidases, proteases, amylase, lipase etc. Also, certain cells that separate out from pancreatic epithelium make clusters of cells surrounded by mesoderm.

1665_Permissive Interaction - Pancreas Development.png

Figure: Permissive Interaction

These cells are the endocrine cells, the islets of Langerhans, generating hormones such as insulin, glucagon and somatostatin. So the exocrine and endocrine cells arise from epithelium of embryonic gut. Growth of pancreas depends on the associated mesoderm. If in a 9-day old embryo, the pancreatic mesoderm and ectoderm are separated from one other, there will not be any additional development. But if they are recombined in a culture medium, both exocrine and endocrine cells differentiate normally. As well, instead of the pancreatic mesenchyme, if the mesenchyme from other regions like mesenchyme from salivary gland region is, substituted general pancreatic cells still differentiate. Somites which produce muscles and cartilage cells can as well induce pancreatic endoderm to develop normally. Even extracts of embryo can induce the pancreatic endoderm. All these results suggest that by 9th day of embryonic life of mouse, the pancreatic endoderm is already determined or committed and just only a non-specific signal from mesoderm is enough for it to complete the development. The mesoderm can be from any region but have to be in proximity to the endoderm.


Related Discussions:- Permissive interaction - pancreas development

Preet, what is microbiology

what is microbiology

What are examples of nematodes, What are examples of nematodes? Ascaris...

What are examples of nematodes? Ascaris, hookworm and filaria, all parasites of humans, are instance of nematodes (also called as roundworms).

Cell Division, What is the difference between Mitosis and Meosis?

What is the difference between Mitosis and Meosis?

Tropical seasonal forests - ecosystem, Tropical seasonal forests - Ecosyste...

Tropical seasonal forests - Ecosystem Tropical seasonal forests occur in regions where total annual rainfall is very high but segregated into pronounced wet and dry periods. T

How can you describe pleural effusion, Q. How can you describe Pleural Effu...

Q. How can you describe Pleural Effusion? Fluid has a density indistinguishable from soft tissue on a radiograph. Pleural fluid tends to accumulate in the deepest part of the

Explain working of cerebral cortex, Q. Explain working of Cerebral Cortex? ...

Q. Explain working of Cerebral Cortex? Cerebral Cortex/Cerebrum: The cerebrum or the cortex is the large part of the brain and is associated with the cognitive functions of the

Determine the foos sources of cyanocobalamin, Determine the Foos Sources of...

Determine the Foos Sources of cyanocobalamin? Vitamin B I2 is unique among vitamins in the sense that it is mostly found in foods of animal origin but is not generally present

What are the cytoplasmic structures present in animal cells, Q. What are th...

Q. What are the main cytoplasmic structures present in animal cells? The main cytoplasmic structures of the cell are the centrioles, the cytoskeleton, mitochondria, peroxisomes

Locomotion in earthworm, LOCOMOTION IN EARTHWORM - By contrection & rel...

LOCOMOTION IN EARTHWORM - By contrection & relaxation of muscles waves are formed in body, generally from posterior to anterior. Setae are helpfull in locomotion. Rate of lo

Factors limiting the productivity of aquatic habitats, Factors Limiting the...

Factors Limiting the Productivity of Aquatic Habitats Sunlight and oxygen are the two most important limiting factors of the aquatic ecosystems. This distinguishes them from t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd