Pathophysiology of bronchial asthma, Biology

Assignment Help:

Pathophysiology

Asthma result from several physiological alterations, including altered immunologic response, increased airways resistance, increased lung-compliance, impaired mucociliary function. Asthma resulting from the antigen-antibody reaction in which chemical mediators such as histamine, eosinophilic factor etc. caused constriction of smooth muscles of both the large and small airways resulting in bronchospasm, increased capillary permeability resulting in mucosal oedema and increased mucus production.

Bronchospams causes increased airway resistance and obstruction to air flow in and out of lungs. The lung become hyperinflated resulting in increased lung compliance. The increased mucus production can cause formation of mucus plugged which can further block the airway. Impaired mucocilliary function, hypertrophy of mucus-secreting glands, thickened mucus and slowed ciliary movement are common findings in persons with asthma. During an attack, increased mucus production combined with slowed clearance of mucus due to decreased ciliary movement results in increased water loss from mucus. Mucus becomes viscous, forming a mucus plug which may block airways.

Increased airway resistance and hyperinflation can increase the work of respiratory muscles resulting in muscle fatigue and exhaustion. Resulting hypoventilation in severe cases lead to respiratory acidosis, and even death.


Related Discussions:- Pathophysiology of bronchial asthma

What are the major representatives of the pteridophytes, Q. What are the ma...

Q. What are the major representatives of the pteridophytes? Is this plant group phanerogamic or cryptogamic? The better known pteridophytes are the ferns and the maidenhairs, f

Define limitations for underwater weighing method, Define Limitations for u...

Define Limitations for underwater weighing method? This method is expensive, time consuming and usually requires a lot of equipment and space. The subject needs to be

What are the main events of the final mitotic period, What are the main eve...

What are the main events of the final mitotic period? The final mitotic phase is telophase. In telophase the following events happens: decondensation of chromosomes, every set

In which area dietitians works, In which area Dietitians works Dietitia...

In which area Dietitians works Dietitians can work in a variety of areas, as already mentioned earlier, many of these are in the  Hospitals or in  the community  as  'Clinical

What are important terms in accommodation and convergence, What are importa...

What are important terms in accommodation and convergence? Accommodation and Convergence In this section some important terms are included: a. How a person is able to foc

Explain the vitamin k dependent proteins, Explain the Vitamin K dependent p...

Explain the Vitamin K dependent proteins? The four vitamin K-dependent procoagulants (factor II or prothrombin, and factors VII, IX, and X), about which we studied above, are s

Who was charles darwin, Who was Charles Darwin? The Charles Darwin was ...

Who was Charles Darwin? The Charles Darwin was an English naturalist born in 1809 and considered the father of the theory of evolution. By the end of the year 1831, before turn

Joints, JOINTS - The structural arrangement of tissues which connect 2 ...

JOINTS - The structural arrangement of tissues which connect 2 or more bones together at their place of meeting is called a joint. Study of joint is arthrology. Joint make the

Thermal properties-specific heat-water properties, Thermal Properties ...

Thermal Properties The range of temperature variatidn in the aquatic environment is smaller in comparison to air. This means the rate of change of temperature is slower in the

Amphioxus, elementatr cannal and feeding mechenism

elementatr cannal and feeding mechenism

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd