Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
The interactions between the human host and selected microorganisms that culminate in IE involve the vascular endothelium, hemostatic mechanisms, the host immune system, gross anatomic abnormalities in the heart, surface properties of microorganisms, and peripheral events that initiate bacteremia. Endothelial damage results in platelet-fibrin deposition, which in turn is more receptive to colonization by bacteria than is the intact endothelium. It is hypothesized that platelet-fibrin deposition occurs spontaneously in persons vulnerable to endocarditis and that these deposits, called nonbacterial thrombotic endocarditis (NBTE) are the sites at which micro organisms adhere during bacteremia to initiate IE. Bacteremia is the initiating event that ultimately converts NBTE to IE. Bacteremia rates are highest for events that traumatize the oral mucosa, particularly the gingiva, and progressively decrease with procedures involving the genitourinary tract and the gastrointestinal tract.
The platelet-thrombin deposits are found at the valve closure-contact line on the atrial surfaces of the mitral and tricuspid valves and on the ventricular surfaces of the aortic and pulmonic valves, the sites of infected vegetations in patients with IE. Three hemodynamic circumstances may injure the endothelium, initiating NBTE: (1) a high velocity jet impacting endothelium (2) flow from a high to a low pressure chamber and (3) flow across a narrow orifice at high velocity. Flow through a narrowed orifice, as a consequence of venturi's effect, deposits bacteria maximally at the low-pressure sink immediately beyond an orifice or at the site where a jet stream impacts a surface.
To cause IE, the organism must be able to persist and propagate on the endothelium. This requires resistance to host defenses. The complement-mediated bactericidal activity of serum limits the ability of susceptible aerobic gram-negative bacilli to cause IE. Those organisms that most frequently cause endocarditis adhere more vigorously in vitro to cardiac valves than do organisms that rarely cause IE.
Explain Preparation of burette for Estimation of Reducing Sugar by Fehling Soxhlet? Preparation of burette - Take a 50 ml burette. 1. Fix the burette into the burette holder
Phylum Coelentrat a : (9,000 'species) The body is radial and made up of two cell layers. Gastro-Vascular cavity is saclike, tentacles and stinging cells are present. They may
OXIDATION OF PYRUVATE TO ACETYL CoA The oxidation of pyruvate to acetyl CoA is the irreversible route from glycolysis to the citric acid cycle. What is citric acid cycle?
Particulates: These are suspended droplets, solid particles or mixture of two. So all the atmospheric substances that are not gases are called particulates. A number of term
Q.How is it produced and what is the function of gastrin in the digestive process? The existence of food in the stomach stimulates the secretion of gastrin that in its turn tri
sir i want standard protocol to extract dna from banana leaves
State the term in brief -Asconoid sponge? Of the three different sponge architectures, it is the simplest. It comrpsies a central choanocyte lined spongocoel which opens to the
(1) It should have high "calorific value" or heat content. (2) It should have "moderate ignition temperature". (lgnition temperature is the minimum temperature at which it s
Tall (T) plants are dominant and short (t) plants are recessive. Two heterozygous tall plants are crossed. What percentage of the offspring will be tall?
Ribavirin (Copegus, Rebetol, and others) Combination treatment of HCV with peginterferon alfa and oral ribavirin has produced higher sustained response rates than peginterfero
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd