Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Metals and Melting practices - alloy, Metals and Melting Practices - Alloy,...

Metals and Melting Practices - Alloy,Blowing,Carbon Monoxide Normal 0 false false false EN-IN X-NONE X-NONE Microsoft

Magnesium and its alloys, Magnesium And Its Alloys Magnesium is a light...

Magnesium And Its Alloys Magnesium is a light metal along with density of 1.74 g/cm 3 . Magnesium is more costly than aluminium as density 2.74 g/cm 3 along with which it comp

Evaluate the absolute velocity of jet, A jet of water moving at 8 m/sec. im...

A jet of water moving at 8 m/sec. impinges on a concave-shaped vane to deflect the jet through 120 o when stationary. If the vane is moving at 5 m/sec., calculate the angle of jet

Plate clutch pressure-clutch slipping, Plate clutch pressure:  Check plate...

Plate clutch pressure:  Check plate clutch pressure for any step using a straight edge.

Measurement of river water levels, Q. Measurement of river water levels? ...

Q. Measurement of river water levels? In designing bridges and other engineering structures on rivers, maximum discharge and highest flood level form essential data for design

ESSENTIALS OF PROJECT MANAGEMENT, Ask qu1. A small maintenance project cons...

Ask qu1. A small maintenance project consists of the following 10 jobs, whose precedence relationships are identified by their node numbers: JOB NODE NUMBERS ESTIMATED DURATION (DA

Determine controllability matrix – open loop control system, An open-loop c...

An open-loop control system has the following state-space model: (a)  Determine the characteristic equation for the open-loop control system. (b)  Determine the characte

Theory of production process, In Grey Cast Iron, carbon is present in -----...

In Grey Cast Iron, carbon is present in ------------form while in white cast iron, it is found in ----------- form.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd