Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Theory of machine, Kleines contruction for slider mechanism

Kleines contruction for slider mechanism

Basic elements of flashbutt welding, Basic elements of flashbutt welding ...

Basic elements of flashbutt welding A flash butt welding machine is mainly comprised of a Main frame Stationary Platen Moving Platen Clamping mechanism Transf

Globular transfer, Globular Transfer Globular transfer  is characterise...

Globular Transfer Globular transfer  is characterised by a drop size of greater diameter than that of the electrode wire. The large drop is easily acted on by gravity, generall

Draw the shear force diagram of beam, Draw the shear force diagram of beam:...

Draw the shear force diagram of beam: Draw the shear force diagram (SFD) & bending moment diagram (BMD) for the beam illustrated in Figure . Solution Reaction at the s

Change in gravitational force, prove that the weight of a body at an elevat...

prove that the weight of a body at an elevation of h from sea level is expressd by the equation

Hill roads - road under special conditions, Hill Roads: Alignment ...

Hill Roads: Alignment Selection and Geometric Design Standards Here, you have already learnt how an alignment of a hill road has to be selected. The selection of a g

Computerized scheduling and control manufacturing systems, Characteristics...

Characteristics Computerized Scheduling And Control Manufacturing Systems Introduction This section illustrates the unique characteristics of CCS or Computer Controlled Sc

Write importance of molliers diagram, Describe the key terms i. Write t...

Describe the key terms i. Write two differences between boiler and turbine. ii. Compare the rankine cycle with carnot cycle in terms of efficiency and work ratio iii.

Zeroth law - thermodynamics, Equalit y of Temperature: Two systems ar...

Equalit y of Temperature: Two systems are having equal temperature if there are no changes in their properties when they are kept in thermal contact with each other. Zer

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd