Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Calculation of seismic response loads, Q. Calculation of seismic response l...

Q. Calculation of seismic response loads? The seismic design requirements and the specification of criteria variables for the calculation of seismic response loads for the desi

Calculate the normal force, Problem You are playing tetherball because ...

Problem You are playing tetherball because you are seven years old and you have nothing better to do.  If the tetherball has a mass of 1 kg and the rope is 1.5 m long and can w

If crankshaft oil seal seating area found ok, If crankshaft oil seal seatin...

If crankshaft oil seal seating area found ok : Replace with a new oil seal and ensure the seal seats in the stator plate properly and while fixing the stator plate ensure using sta

#mechanics of materials, What is maximum shear stress in mechanics of mater...

What is maximum shear stress in mechanics of materials ? Derivation for maximum and minimum shear stress seperately.

Represent moment graphically - mechanics, Represent moment Graphically: ...

Represent moment Graphically: How you represent moment Graphically? Sol.: Consider force F which is represented in magnitude and direction, by   line AB . L

Plant layout and equipment spacing, Q. Plant layout and equipment spacing? ...

Q. Plant layout and equipment spacing? Layout refers to the location of plants (and process/power units within the plants and associated utilities (or balance of plant)) as wel

Superheated steam - thermodynamics, Superheate d Steam: When the dry ...

Superheate d Steam: When the dry saturated steam is heated further at constant pressure, the temperature of it rises up above the saturation temperature. This rise in tempera

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd