Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Fluid Mechanics, I would like a help for my fluid mechanics assignment

I would like a help for my fluid mechanics assignment

Polar modulus , Pola r Modulus(Z p ):   It is the ratio of polar m...

Pola r Modulus(Z p ):   It is the ratio of polar moment of the inertia to outer radius. Z p = J / R Polar Modulus of solid body ( Z p ) =[  ?/32. D 4 ]/ D

Tropical geometric information of solids, Tropical geometric information of...

Tropical geometric information of solids A face is surrounded by a set of vertices. Using the right-handed rule, the ordering of these vertices for describing a particular face

Bolt Group Bending Moment, What is the Maximum bolt bending moment in a gro...

What is the Maximum bolt bending moment in a group for four equally spaced bolts?

Electrodes- stainless steel electrodes, Stainless Steel Electrodes A vari...

Stainless Steel Electrodes A variety of stainless steel electrodes are now being manufactured to produce weld metal similar to composition of most base metals. However, the analy

Product engineering, what is part proliferation and how to reduce it ?

what is part proliferation and how to reduce it ?

Process of alloy materials sampling, Q. Process of Alloy Materials Sampling...

Q. Process of Alloy Materials Sampling? The following alloy-materials require a minimum of 10% per lot representative PMI sampling. If any incorrect material is found in repres

Discover the fixing torques set up at the ends of the shaft, Discover the f...

Discover the fixing torques set up at the ends of the shaft: A solid shaft 6.5 m long is securely fixed at each of the end. A torque of 91 Nm is applied to the shaft at a sect

Dimension styles-autocad, Dimension Styles Dimension styles are the bas...

Dimension Styles Dimension styles are the basic method used to control the way dimensions look . Using Dimension styles you can change the text font, arrow head style,relativ

Determine reactions at supports of loaded beam, Determine reactions at supp...

Determine reactions at supports of loaded beam: Determine reactions at supports A and B of loaded beam as shown in the figure given below.     Sol.: First co

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd