Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Pressure and temperature in unfired pressure vessels, Q. Pressure and Tempe...

Q. Pressure and Temperature in Unfired pressure vessels? The design pressures and coincident maximum and minimum metal temperature, shall be determined by carefully considering

Define maximum allowable working pressure, Q. Define Maximum Allowable Work...

Q. Define Maximum Allowable Working Pressure? The MAWP to be marked on the Section VIII nameplate is defined as the maximum gauge pressure permissible at the top of a completed

Computational fluid dynamics package , Cooling of storage tanks: A res...

Cooling of storage tanks: A research involving using a bench top scale wind tunnel to investigate heat losses from storage tanks. A series of small scale model tanks have bee

Logistics - inbound and outbound, Logistics - Inbound and Outbound: Lo...

Logistics - Inbound and Outbound: Logistics plays a vital role in designing and shaping of SCM in a firm. Without an effective logistics system the effectiveness of the firms

Two wheeler industry growth, TWO WHEELER INDUSTRY GROWTH:  In world repres...

TWO WHEELER INDUSTRY GROWTH:  In world represents one of the largest two wheeler markets in the world with an estimated size of 5.4 million units a year. Two wheelers are used ext

Monitoring system in gas metal arc welding, WHICH IS THE BEST ONLINE MONITO...

WHICH IS THE BEST ONLINE MONITORING SYSTEM FOR GAS METAL ARC WELDING

Loosening a part with multiple fasteners services tips, Loosening a Part wi...

Loosening a Part with Multiple Fasteners: Loosening a part with multiple fasteners should be done from the outside to inside in a criss-cross pattern, loosening the small fastener

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd