O-linked oligosaccharides , Biology

Assignment Help:

Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:

?   O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.

?   N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2   where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.

 


Related Discussions:- O-linked oligosaccharides

Explain the role of dietitian''s in feeding dilemmas, Explain the role of d...

Explain the role of dietitian's in feeding dilemmas Usually, the dietitian's role in  feeding dilemmas is seen as secondary and the physician's role  is the  focus. In reality,

Protein of animal origin - meat, Protein of Animal Origin - Meat Meat:...

Protein of Animal Origin - Meat Meat: Skeletal or striated muscles are used for food purposes. Flesh of cattle, sheep and swine comprise most of the meat contents. Edible mea

Consumers-biotic components , Consumers Heterotrophs (other nourishing...

Consumers Heterotrophs (other nourishing) are incapable of photosynthesis and depend on organic food derived from animals, plants or both. Consumers can be divided into two br

What are genotypes and phenotypes, The agouti locus in mice has three allel...

The agouti locus in mice has three alleles: A is recessive and confers a black coat, A is dominant to a and confers an agouti coat, and AY is dominant to both and confers a yellow

What do you mean by astigmatism and presbyopia, Q. What are astigmatism and...

Q. What are astigmatism and presbyopia? Presbyopia is the visual impairment in which there is loss of the cililary muscle strength thus reducing the ability of the crystalline

What is chylomicrons , Chylomicrons, the widest of the lipoproteins, are...

Chylomicrons, the widest of the lipoproteins, are synthesized in the intestine. They including ingested triacylglycerols to other tissues, mainly skeletal muscle and adipose tissue

What do you understand by pharynx, What do you understand by Pharynx? T...

What do you understand by Pharynx? The region of digestive tract between the mouth and esophagus. In most animals it's muscular and forces food into the digestive tract which l

What is the group of the phylum chordata, What is the group of the phylum C...

What is the group of the phylum Chordata that first colonized the terrestrial environment? From which habitat did they come? Amphibians, partially aquatic partially terrestrial

What is the chemical content of those organelles, Q. On which organelle of ...

Q. On which organelle of the cell structure does intracellular digestion depend? What is the chemical content of those organelles? Intracellular digestion take place by the act

How do the sodium and potassium ions maintain the neuron, How do the sodium...

How do the sodium and potassium ions maintain the resting potential of the neuron? The plasma membrane of the neuron when at rest maintains an electric potential difference amo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd