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Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.
How to Planning the Daily Diet for Underweight Patients? As mentioned above you need to add calories gradually to the diet. A practical way of doing so is to take the present i
Unsaturated fatty acids show different types of isomerisms. We have already learnt about the.concept of isomerism in the last unit. You would realize that fatty acids with s
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Q. Which kind of chemical bond maintains the pairing of each chain in the DNA molecule? To form the DNA molecule, purine bases bind to pyrimidine bases by intermolecular bonds
Categorisation of Major Brain Functions As a framework, the major brain functions typically divided into modalities and domains. The major modalities are motor function and th
Fine Structure of Pollen Tubes Grown in Vitro The growth in pollen tubes is exclusively restricted to the tip. Cytochemical analysis reveals the pollen tip zone to be rich in
Beginning with the entry of fatty acid into target cells, describe in detail how inactivation of carnitine can lead to a high level of fatty acids in the blood.
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What is Atrial Switches Operations (Senning or Mustard Operation) ? In transposition of the great arteries there is ventriculo arterial discordance whereby aorta arises from ri
Explain Doxycycline Doxycycline, which frequently causes gastrointestinal disturbances and can cause photosensitivity and vaginitis, offers an inexpensive once-daily alternative
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