Mixed aortic stenosis and regurgitation, Biology

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Mixed Aortic Stenosis and Regurgitation :  The combined aortic valve stenosis and regurgitation may be of congenital or acquired aetiology, as in aortic stenosis. Most commonly in our country it is due to rheumatic heart disease. An episode of infective endocarditis on a previously stenotic valve may precipitate acute regurgitation.

Many patients with severe aortic stenosis may have mild regurgitation. Those with severe regurgitation may have mild aortic stenosis also. A few may have balanced lesions. Symptoms of one or the other may dominate. They have a particularly unfavourable outlook as" there is both pressure and volume overload on the ventricle.

When indicated, the operation is valve replacement as valve repair procedures are usually unsuccessful.

 


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