Mendelian randomization, Advanced Statistics

Assignment Help:

Mendelian randomization is the term applied to the random assortment of alleles at the time of gamete formation, a process which results in the population distributions of genetic variants which are generally independent of the behavioural and environmental factors which typically confound epidemiologically derived associations between the putative risk factors and disease. In some of the circumstances taking the advantage of Mendelian randomization might provide an epidemiological study with properties of a randomized comparison, for instance, a randomized clinical trial. In particular, the use of the Mendelian randomization might allow causal inferences to be drawn from epidemiological studies, typically using the instrumental variable estimator.


Related Discussions:- Mendelian randomization

Multimodal distribution, what is pdf,mean & variance for multimodal distrib...

what is pdf,mean & variance for multimodal distribution?

Rates of return, An investor with a stock portfolio sued his broker, claimi...

An investor with a stock portfolio sued his broker, claiming that a lack of diversification in his portfolio had led to poor performance. The data, shown below, are the rates of re

Describe law of likelihood, Law of likelihood : Within framework of the sta...

Law of likelihood : Within framework of the statistical model, a particular set of data supports one statistical hypothesis or assumption better than another if the likelihood of t

Describe multiple imputation, Multiple imputation : The Monte Carlo techniq...

Multiple imputation : The Monte Carlo technique in which missing values in the data set are replaced by m> 1 simulated versions, where m is usually small (say 3-10). Each of simula

Explain interim analyses, Interim analyses : An analysis made before the pl...

Interim analyses : An analysis made before the planned end of a clinical trial, typically with the aim of detecting the treatment differences at the early stage and thus preventing

Factor scores, The values assigned to factors for the individual sample uni...

The values assigned to factors for the individual sample units in a factor analysis. The most common approach is "regression method". When the factors are seen as the random variab

Deviance, The measure of the degree to which the particular model differs f...

The measure of the degree to which the particular model differs from the saturated model for the data set. Explicitly in terms of the likelihoods of the two models can be defined a

Missing data - reasons for screening data, Missing Data - Reasons for scree...

Missing Data - Reasons for screening data In case of any missing data, the researcher needs to conduct tests to ascertain that the pattern of these missing cases is random.

Explain influence statistics, Influence statistics: The range of statistic...

Influence statistics: The range of statistics designed to assess the effect or the in?uence of an observation in determining results of the regression analysis. The general approa

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd