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Mendelian randomization is the term applied to the random assortment of alleles at the time of gamete formation, a process which results in the population distributions of genetic variants which are generally independent of the behavioural and environmental factors which typically confound epidemiologically derived associations between the putative risk factors and disease. In some of the circumstances taking the advantage of Mendelian randomization might provide an epidemiological study with properties of a randomized comparison, for instance, a randomized clinical trial. In particular, the use of the Mendelian randomization might allow causal inferences to be drawn from epidemiological studies, typically using the instrumental variable estimator.
The phrase first spoken by one of the witches in Macbeth. Now this is used to describe the exponential rise in the number of possible locations in the multivariate space as dimensi
Case-cohort study : The research design in epidemiology which involves the sampling of controls at the outset of the study that is to be compared with the cases from the cohort. Th
An oil company is considering whether or not to bid for an offshore drilling contract. If they bid, the value would be $600m with a 65% chance of gaining the contract. The company
Common cause failures (CCF): Simultaneous failures of the number of components due to a same reason. A reason can be external to the components, or it can be the single failure wh
Misspecification is the term is applied to describe the assumed statistical models which are incorrect for one of the several of reasons, for instance, using the wrong probability
A mixture of benzene, toluene, and xylene enters a two-stage distillation process where some of the componentsare recovered. The distillation process operates at steady-state condi
Quasi-experiment is a term taken in use for studies which resemble experiments but are weak on some of the characteristics, particularly that allocation of the subjects to groups
The graphic representation of the alternatives in a decision making problem which summarizes all the possibilities foreseen by the decision maker. For instance, suppose we are give
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The function of a variable t which, when extended formally as a power series in t, yields factorial moments as the coefficients of the respective powers. If the P(t) is probability
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