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Megaloblastic Anaemia
Megaloblastic anaemia refers to the abnormal development of red cells i.e. megaloblasts in the bone marrow.
Etiology
It is due to lack of folic acid and/or vitamin B12 in the diet. The other associated factor are, protein deficiency states, chronic or recurrent diarrhoea, malabsorption syndrome, chronic hepatic disease, anticonvulscent drugs and hemolytic anaemias.
What is Iodoacetate inhibitor Iodoacetate is the inhibitor of glyceraldehyde-3-phosphate dehydrogenase.
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