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By introducing their model of neural excitability in 1952, Alan Lloyd Hodgkin and Andrew Huxley not only shed light on the mechanism underlying a very important phenomenon in Physiology (i.e. the generation and propagation of electrical signals in neurones), but they also introduced a mathematical formalism for modeling similar phenomena in a large variety of excitable cells. Therefore, it is only natural that there is a large number of neural models that are built on the basic concepts introduced by the two aforementioned researchers. One such model is the following:
where IL, INa, IK, IA and ICaT are leakage, transient sodium, persistent potassium, transient potassium and transient calcium currents, respectively, and I(t) is any time-dependent externally injected current. The dynamic activation and inactivation variables x, where x 2 fm; h; n; a; b;M;Hg follow rst order relaxation kinetics:
Find out ratio of upper end area to lower end area of bar of uniform strength Sol : The figure given to us shows a bar subjected to external tensile load P. If bar had be
Butt joints- formed by placing the plates edge to edge and welding them. Grooves are sometimes cut (For thick plates) on the edges before welding. According to the shape of the gro
Compute the coefficient of friction at block: The frame shown in Figure rotates about a vertical axis. The coefficient of friction under block A is 0.4. Compute the coefficien
case study for factors affecting process design decisions
in the spiral or helical gears- have meshing gear different helix angle?
Explain the Tool Signature The tool angles have been standardized by the American standards association. The seven important elements comprise the signature of the cutting tool
What do you understand by straight line mechanism ? Describe with a neat sketch the working and construction of any three types of straight line mechanism. Derive a mathematical
1. I have a data for displacement versus time ( graph) then I want to get the velocity and acceleration graphs from the displacement.How can I get it?
how do we solve circuits using the mesh current method
Kennedy’s Theorem: According to this theorem the relative instantaneous centres on whichever three bodies that contain motion relative to each other are collinear. Higher Pa
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