Maximal conductances and reversal potentials, Mechanical Engineering

Assignment Help:

By introducing their model of neural excitability in 1952, Alan Lloyd Hodgkin and Andrew Huxley not only shed light on the mechanism underlying a very important phenomenon in Physiology (i.e. the generation and propagation of electrical signals in neurones), but they also introduced a mathematical formalism for modeling similar phenomena in a large variety of excitable cells. Therefore, it is only natural that there is a large number of neural models that are built on the basic concepts introduced by the two aforementioned researchers. One such model is the following:

2005_Membrane capacitance.png

where IL, INa, IK, IA and ICaT are leakage, transient sodium, persistent potassium, transient potassium and transient calcium currents, respectively, and I(t) is any time-dependent externally injected current. The dynamic activation and inactivation variables x, where x 2 fm; h; n; a; b;M;Hg follow rst order relaxation kinetics:

1139_Membrane capacitance1.png


Related Discussions:- Maximal conductances and reversal potentials

Explain the difference between si and ci engines, Difference between SI and...

Difference between SI and CI engines SI engine stands for spark ignition engine while CI engine stands for compression ignition engine. SI engine works on the principle of w

Determine the number of cycles - crack propagation, Determine the number of...

Determine the number of cycles - crack propagation: The plate of above Example  contained a crack of 50 mm length in the centre before it was subjected to cyclic stress. Deter

[email protected], how i can know moulair plant calculation?

how i can know moulair plant calculation?

Determine the heat rejection, In an engine working on Diesel cycle inlet pr...

In an engine working on Diesel cycle inlet pressure and tem are 1 bar and 17 o c respectively. Pressure at the end of adiabatic compression is 35 bar. He ratio of expansion i.e. af

Engineering mechanics, difference between coplanar and noncoplanar force sy...

difference between coplanar and noncoplanar force system

Project quality plan, Project Quality Plan Design verification require...

Project Quality Plan Design verification requirements for a project are to be established in the Quality Plan sub-section of the Project Execution Plan. The Lead Mechanical E

Air transportation, AIR TRANSPORTATION: Air transportation has grown r...

AIR TRANSPORTATION: Air transportation has grown rapidly all over the world and in India too. Its main advantages are speed, good safety record, military use, ability to serve

Illustrate the electromagnetic clutch, Illustrate the Centrifugal Clutch in...

Illustrate the Centrifugal Clutch in Detail with neat sketch ? Illustrate the Electromagnetic Clutch in Detail with neat sketch ? Illustrate the Diaphragm spring Clutch in

Sleepers - permanent way, Sleepers: The sleeper is the part of the tr...

Sleepers: The sleeper is the part of the track on which the rails rest. Its functions are : (a) To hold the rails to the correct gauge. (b) To transmit and distribute t

Mechanical vibrations, The suspension system of a car is modelled as having...

The suspension system of a car is modelled as having an effective stiffness of 5x10 6 (N/m) and an effective mass of 750 (kg). The car is travelling over a road with bumps that ca

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd