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• Cyclins accumulate during the G1, S, and G2 phases of the cell cycle. • By the G2 checkpoint (the red bar in the figure), enough Cyclin is available to form MPF complexes (aggregations of Cdk and Cyclin) which initiate mitosis.
o MPF apparently functions by phosphorylating key proteins in the mitotic sequence.
• Later in mitosis, MPF switches itself off by initiating a process which leads to the destruction of Cyclin
o Cdk, the non-Cyclin part of MPF, persists in the cell as an inactive form until it associates with new Cyclin molecules synthesized during Interphase of the next round of the cell cycle.
Medical status of the patient Conditions like osteoporosis, history of radiotherapy, use of bisphosphonates which can affect the success of the treatment should be considered b
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what is the biological significance of the skeleton and supporting system in animals
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Dextran is a glucose polymer where the glucose residues are mainly related by α1-6 bonds. Moreover, a few branches also happen. These are classically formed by α1-2, α1-3 or α1-4 b
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why uracil is present in rna and thymine in dna?
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