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Maturation Phase
The Maturation phase characterizes he transformation of diploid primary spermatocytes into haploid spermatids. The primary spermatocyte divides meiotically to produce two secondary spermatocytes each with a haploid nucleus. Each of the secondary spermatocytes undergoes second meiotic division to produce two haploid spermatids. Each spermatid undergoes an intracellular differentiation to produce spermatozoa. The process of intracellular differentiation of a spermatid into spermatozoa is known as spermiogenesis. We shall now describe the spermiogenesis process in detail.
Figure: Section of seminiferous tubules in a human testis showing different stages of spermatogenesis
Maintenance Therapy A complete remission implies a clinical, haematological and bone marrow remission. For remission therapy drugs like, methotrexate cyclophospharnide and 6-
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