Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Juxtaglomerular Apparatus
The autoregulation of renal blood flow involves a neuroendocrine mechanism related to the juxtaglomerular apparatus in the kidney.
Figure: Structure of the juxtaglomerular apparatus in mammals
When the afferent arterial blood pressure is low, the stretch sensitive receptors of the arterioles initiate nerve impulses which induce the secretion of a proteolytic enzyme called renin by the juxtaglomerular cells into the blood. This enzyme causes the release of a decapeptide called angiotensin-I from a large globular plasma protein known as angiotensinogen. Another proteolytic enzyme from the plasma, the converting enzyme, removes two amino acids from angiotensin-I to form an octapeptide called angiotensin-II. Angiotensin-II is about 200 times more powerful than norepinephrine in its lasopressor activity. It increases the blood pressure by two mechanisms. Firstly, it acts on the smooth muscle of the arterioles and causes strong vasoconstriction. Secondly, it stimulates the secretion of aldosterone by the adrenal cortex. Aldosterone enhances the uptake of Na+ by the kidney tubules and hence causes a rise in the plasma Na+ level. This results in an increase in the extracellular fluid volume and consequently an elevation in blood pressure. Angiotensin-II is degraded by an enzyme called Angiotensinase, present in plasma.
IMPLAN TA TIO N - Attachement of blastocyst on the endometrium of the uterus is called implantation. Generally it occurs 7th day after fertilisation. (6-10 days). Blas
Metabolic Significance of HMP Pathway Having gone through the HMP pathway, you would have got some idea about the significance of this alternative oxidative pathway for t
In diabetes mellitus counsellor help the diabetic patient to cope up with the stress and take own decision for their treatment and life style changes. Decision making capacity of
Q. What is the ecological role of earthworms? Earthworms have an important ecological role as they eat decomposing organic material. They also dig tunnels in the subsoil allowi
What is phosphorylation? What are some biological processes in which phosphorylation plays a critical role? Phosphorylation is the name given to processes of the addition of ph
Galactose Metabolism Galactose goes to the liver via portal blood and is phosphorylated by galactokinase togalactose- 1 -phosphate (GIP) using ATP as a phosphate donor as s
Elaborate Proteins? Proteins: Proteins are the primary constituents of most living cells. Proteins are important components of cell membranes, and they form structures such
Q. Illustrate Physiological Evidence ? Physiological and biochemical evidence is providing data of increasing importance to plant systematic. Recently, it has become apparent t
Why doesn't a long lasting vaccine against common cold exist yet? Viruses that show a high mutation rate like the virus that causes the common cold escape simply from the actio
Which of the following is true for the epithelial cells of the kidney proximal tubule? A. The sodium-glucose co-transporter in the luminal membrane is responsible for the net f
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd