Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Juxtaglomerular Apparatus
The autoregulation of renal blood flow involves a neuroendocrine mechanism related to the juxtaglomerular apparatus in the kidney.
Figure: Structure of the juxtaglomerular apparatus in mammals
When the afferent arterial blood pressure is low, the stretch sensitive receptors of the arterioles initiate nerve impulses which induce the secretion of a proteolytic enzyme called renin by the juxtaglomerular cells into the blood. This enzyme causes the release of a decapeptide called angiotensin-I from a large globular plasma protein known as angiotensinogen. Another proteolytic enzyme from the plasma, the converting enzyme, removes two amino acids from angiotensin-I to form an octapeptide called angiotensin-II. Angiotensin-II is about 200 times more powerful than norepinephrine in its lasopressor activity. It increases the blood pressure by two mechanisms. Firstly, it acts on the smooth muscle of the arterioles and causes strong vasoconstriction. Secondly, it stimulates the secretion of aldosterone by the adrenal cortex. Aldosterone enhances the uptake of Na+ by the kidney tubules and hence causes a rise in the plasma Na+ level. This results in an increase in the extracellular fluid volume and consequently an elevation in blood pressure. Angiotensin-II is degraded by an enzyme called Angiotensinase, present in plasma.
SOMATOFORM DISORDERS: The term 'Neurosis' was first introduced in 1769 by William Cullen (1710- 1790). Till later part of nineteenth century, anxiety disorders were conspicu
What is Respiratory System explain their functionality ? The respiratory system is responsible for the transport of oxygen and carbon dioxide from outside the body to and from
Q. Explain about Coping mechanism? Coping mechanism is defined as the skill used to reduce stress. In other words, these are consciously used skills. Overuse of coping mecha
Explain about the Ascomycota - Fungi? Ascomycota - Ascomycetes or sac-like fungi have septate mycelium. These are called so because sexual reproduction involves the formation o
Q. Pathophysiology of Cardiac tamponade? Progressive increase in pericardial fluid results in progressive increase in intrapericardial pressure, till a critical volume is reach
What is hemoglobin F? Why does the fetus need a different hemoglobin? Hemoglobin F is the hemoglobin found in the mammalian fetus and hemoglobin A is the normal hemoglobin. Hem
How might stem cells and other tools of "regenerative medicine" be used to treat brain diseases? Fuelled by the hope which stem cells may have the capacity to rebuild virtually
how autophagy help in converting a tadpole larva into adult amphibian
Is monoculture a system that contributes to great biological diversity of an ecosystem? Monoculture means that in a large area a single crop (only single species of plant) is c
What are quantitative data? Give two examples of quantitative data. Quantitative data are data that can be calculated in numbers. Examples contain the dimensions of an objec
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd