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How can the concept of recombination frequency be used in genetic mapping?
The Genetic mapping is the determination of the location of the genes in a chromosome. Besides determining the recombination frequency between numerous different linked genes it is possible to estimate the distance between them in the chromosome. For instance, if a gene A has a recombination frequency of 20% with the gene B, this gene B has recombination frequency of 5% with the gene C and this gene C has recombination frequency of 15% with the gene A, it is possible to assert that the gene A is 20 centimorgans distant from the gene B and that between them lies the gene C at 15 centimorgans of distance from the gene A.
The cystic fibrosis allele occurs in European populations with q=0.02, what fraction of this population can be expected to have cystic fibrosis?
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