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In infant botulism, viable botulinal spores are ingested and upon germination in the intestinal tract, toxin is synthesized. It is confined to infants under a year of age. High number of spores is found in the faeces of infants during the acute phase of the disease. It appears that ingested endospores, which maybe present in honey or other baby foods, germinate in the infant's intestine. C. botulinum then multiplies and produces the exotoxin. The infant becomes constipated, listless, generally weak and eats poorly. Death may result from respiratory failure.
Foot-and-mouth disease Foot-and-mouth disease (FMD) is an extremely contagious viral disease of cloven footed animals most notably cattle, pig and sheep. It is well known for
1. Describe what effects epigenetic modifications such as methylation and acetylation can have in eukaryotic cells, and how these modifications are added or removed from chromatin.
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