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In infant botulism, viable botulinal spores are ingested and upon germination in the intestinal tract, toxin is synthesized. It is confined to infants under a year of age. High number of spores is found in the faeces of infants during the acute phase of the disease. It appears that ingested endospores, which maybe present in honey or other baby foods, germinate in the infant's intestine. C. botulinum then multiplies and produces the exotoxin. The infant becomes constipated, listless, generally weak and eats poorly. Death may result from respiratory failure.
Timing and number of doses It has been common practice to give antibiotics at the time of anesthesia induction, which results in adequate serum and tissue levels of the drugs;
HUMA N RESPIRATORY SYSTEM -
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