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Illustrate the electrophysiology and ion transport of cornea?
Electrophysiology and ion transport of cornea:
The trans-epithelial potential is 25-35 mV. It is almost 50 per cent of short circuit current and is due to C1-ion efflux in tear film, Na-K ATPase at the basolateral membrane with a chloride co-transport and Na-H exchanger and lactate-proton exchanger. These regulate intracellular pH by extrusion of lactate and H ions. Process is regulated by sympathetic corneal nerves. The in vivo epithelial ion transport has a minimal role, when any in corneal deturgescence, when it compared to the endothelium.
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