Illustrate pathology, Biology

Assignment Help:

Q. Illustrate Pathology?

Following rheumatic fever, over next few years to decades, the typical funnel shaped mitral valve assumes a fish mouth appearance. During rheumatic fever endocardium of the leaflets gets inflamed, edematous and develops pin head vegetations at the tips or along the line of closure. These heal with fibrosis resulting in thickening of the leaflets with limited mobility. Some times there may be calcific deposits over the leaflets. The commissures get fused and in diastole the larger anterior leaflet pulls the posterior leaflet anteriorly. This decreases the valve opening in diastole. Thickened and fused chordae further limit the opening of the valve. Subvalvular apparatus, i.e., the chordae may fuse to such an extent that a secondary orifice may develop below the mitral valve limiting the diastolic blood flow. The abnormal valvular flows due to initial valvulitis may further worsen the thickening and fibrosis of the leaflets progressively. The progression may be rapid in some patients due to repeated attacks of rheumatic carditis, genetic or hormonal factors or due to increased hemodynamic load as seen in manual laborers.


Related Discussions:- Illustrate pathology

Hypothalamus and pituitary, Hypothalamus and Pituitary The most obviou...

Hypothalamus and Pituitary The most obvious neuroendocrine link is between the hypothalamus and pituitary. The hypothalamus is a part of the brain which is connected to the pi

Pituitary disorders, PITUITARY DISORDERS - (a) Pituitary Dwarfism . It...

PITUITARY DISORDERS - (a) Pituitary Dwarfism . It is caused by the deficiency of growth hormones (GH) from childhood. It is characterised by small but well porportioned body a

Species diversity-structure of community, Species diversity An importan...

Species diversity An important attribute of a community is its species diversity. The diversity is calculated both by the number of species (richness) and the relative abundanc

Cytoplasmic matrix, Cytoplasmic Matrix ( = cytosol  or Hyaloplasm ) Thi...

Cytoplasmic Matrix ( = cytosol  or Hyaloplasm ) This is the actual protoplasmic  part of the cytoplasm, containing dissolved proteins, electrolytes, glucose, etc. And forming

Offspring, #q1. If offspring exhibit a 3:1 phenotypic ratio, what are the g...

#q1. If offspring exhibit a 3:1 phenotypic ratio, what are the genotypes of a parent?uestion..

Explain about carrier proteins transport substances, How do carrier protein...

How do carrier proteins transport substances across cell membranes? Carrier proteins bind to a molecule of the substance on single side of the membrane, change shape, transpor

Effects of flow limiting stenosis on blood flow, 1) The presence of epicar...

1) The presence of epicardial coronary artery stenosis caused by artherosclerotic plaques is by far the most frequent angiographic finding in any cardiac ischaemic syndrome. 2)

Nerve impulse, NE R VE IMPULSE (IT'S GENERATION) - It is an electr...

NE R VE IMPULSE (IT'S GENERATION) - It is an electro chemical phenomenon manifested through ionic movement across cell membrane. It was discovered by A. L. Hodykin & A

What is resective therapy, Resective therapy Is used to reduce pockets,...

Resective therapy Is used to reduce pockets, correct negative osseous architecture and rough implant surfaces and increase the area of keratinized gingival if needed. Apical

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd