Illustrate pathology, Biology

Assignment Help:

Q. Illustrate Pathology?

Following rheumatic fever, over next few years to decades, the typical funnel shaped mitral valve assumes a fish mouth appearance. During rheumatic fever endocardium of the leaflets gets inflamed, edematous and develops pin head vegetations at the tips or along the line of closure. These heal with fibrosis resulting in thickening of the leaflets with limited mobility. Some times there may be calcific deposits over the leaflets. The commissures get fused and in diastole the larger anterior leaflet pulls the posterior leaflet anteriorly. This decreases the valve opening in diastole. Thickened and fused chordae further limit the opening of the valve. Subvalvular apparatus, i.e., the chordae may fuse to such an extent that a secondary orifice may develop below the mitral valve limiting the diastolic blood flow. The abnormal valvular flows due to initial valvulitis may further worsen the thickening and fibrosis of the leaflets progressively. The progression may be rapid in some patients due to repeated attacks of rheumatic carditis, genetic or hormonal factors or due to increased hemodynamic load as seen in manual laborers.


Related Discussions:- Illustrate pathology

What is the significance of pronephric, What is the significance of Proneph...

What is the significance of Pronephric? The first, or ancestral, kidney that appears in the anterior part of the coelomic cavity and is connected to the archinephric duct. In a

Explain about the electrophoresis, Explain about the Electrophoresis? E...

Explain about the Electrophoresis? Electrophoresis refers to the movement of charged particles because of an external electric field. Because charged molecules can be made to m

Why do roots of many swamp plants have a special morphology, Why do roots o...

Why do roots of many swamp plants have a special morphology? Swamp and marsh plants usually present supporting roots that ramify from portions of the stem above the ground help

The final concentration of the solution, Assume that you have 1 ml of a sol...

Assume that you have 1 ml of a solution of amylase (an enzyme) at a concentration of 15 mg protein/ml. Calculate the volume of diluting buffer that you would have to add to 1.0 ml

Define the recommended dietary allowances of vitamin k, Define the Recommen...

Define the Recommended Dietary Allowances of Vitamin K? Recommended dietary intakes have not been suggested for different age groups or gentler. The safe levels of intake have

Define amylopectin - carbohydrates, Define Amylopectin - carbohydrates? ...

Define Amylopectin - carbohydrates? Amylopectin differs from amylose in being highly branched. Short side chains of about 30 glucose units are attached with α (1-6) linkages ap

Determine about the open head injuries, Open Head Injuries Open head in...

Open Head Injuries Open head injuries are TBIs in which the skull is penetrated, as in gun shot or missile wounds, or in which fragment of bone penetrate the brain substance. O

Long lasting vaccine against common cold, Q. Why does not a long lasting va...

Q. Why does not a long lasting vaccine against common cold exist yet? Viruses that present a high mutation rate like the virus that causes the common cold escape easily from th

Determine the physiological effects phytoestrogens, Determine the Physiolog...

Determine the Physiological Effects phytoestrogens? Little is known about the biologic and physiologic effect of phytoestrogens in humans. Animal studies suggest the following

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd