How would you confirm this disease, Biology

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Question 1 A patient is admitted to the hospital with suspected pulmonary tuberculosis. How would you confirm this disease? Answer the following questions

                  a) Which is the most preferable sample to collect from the patient for diagnosis
                  b) How would you differentiate this disease from other diseases that resemble pulmonary tuberculosis
                  c) Do you think culture is useful in immediate diagnosis of pulmonary tuberculosis? Explain your answer

Question 2 Discuss the role of beta lactamases in bacterial drug resistance. Add a note on identification of multidrug resistant bacterial pathogens in clinical samples


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