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According to the Nernst equation, the equilibrium potential for any ion (Eion) distributed across a membrane is dependent on the internal (Ionin) and external (Ionout) concentrations of the ion (in moles or grams/liter), the valence of the ion, z (an integer), the absolute temperature (°K), Faraday's constant (96,500 coulombs/mole) and the universal gas constant R according to the following relationship: Eion = (RK/zF)2.303 log ([Ion]out/[Ion]in) Assuming that the equilibrium potential for sodium ion across a skeletal muscle is +66 mv at a temperature of 37°C when the external concentration is 145 mM and the internal concentration is 12 mM, evaluate both the magnitude and appropriate units for the universal gas constant, R.
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