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Q. How is hemophilia treated? Why is hemophilia rare in females?
Hemophilia is medically treated with administration of factor VIII in case of hemophilia A or of factor IX in case of hemophilia B by means of blood or fresh frozen plasma transfusions.
A girl with only one affected chromosome does not present the disease since the normal gene of the unaffected other X chromosome produces the clotting factor, Hemophilia A or B is an X-linked recessive inheritance and for a girl to be hemophilic it is necessary for both of her X chromosomes to be affected while boys that have only one X chromosome are more easily affected.
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