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Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting joint null hypothesis.
The fraction of the observed significances at the given α-level is compared to the expected fraction under the joint null and the difference between the two quantities is standardized and this standardized value then maximized over the range of significance levels to provide the higher criticism statistic. This statistic is efficient in assessing whether n normal means are all zero against the alternative that the small fraction is nonzero.
Markers of disease progression : Quantities which form a general monotonic series throughout the course of the disease and assist with its modelling. In uasual such quantities are
calculate absorbance value from concentration
Chebyshev's inequality: A statement about the proportion of the observations which fall within some number of the standard deviations of the mean for any of the probability distri
Chernoff's faces : A method or technique for representing the multivariate data graphically. Each observation is represented by the computer-created face, the features of which are
Weighted least squares is the method of estimation in which the estimates arise from minimizing the weighted sum of squares of the differences between response variable and its pr
Compound symmetry : The property possessed by the variance-covariance matrix of the set of multivariate data when its chief diagonal elements are equal to each other, and in additi
An investor with a stock portfolio sued his broker, claiming that a lack of diversification in his portfolio had led to poor performance. The data, shown below, are the rates of re
Literature controls : The patients with the disease of interest who have received, in the past, one of two treatments under the investigation, and for whom the results have been pu
Advantages and disadvantages of Integrated Economic Statistics
regression line drawn as Y=C+1075x, when x was 2, and y was 239, given that y intercept was 11. calculate the residual
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