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Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting joint null hypothesis.
The fraction of the observed significances at the given α-level is compared to the expected fraction under the joint null and the difference between the two quantities is standardized and this standardized value then maximized over the range of significance levels to provide the higher criticism statistic. This statistic is efficient in assessing whether n normal means are all zero against the alternative that the small fraction is nonzero.
Bioinformatics : Essentially the application of the information theory to biology to deal with the deluge of the information resulting from the advances in molecular biology. The m
when there is tie in sequencing then what we do
Data theory is anxious with how observations are transformed into data which can be analyzed. Data are thus viewed as the theory laden in the sense that the observations can be giv
It is the art of attempting to exchange something quite small and certain, for something which are large and uncertain. Gambling is big business; in the US, for instance, it is at
Grade of membership model: This is the general distribution free method for the clustering of the multivariate data in which only categorical variables are included. The model ass
Computer-aided diagnosis : The computer programs which are designed to support clinical decision making. In common, such systems are based on the repeated application of the Bay
Cluster sampling : A method or technique of sampling in which the members of the population are arranged in groups (called as 'clusters'). A number of clusters are selected at the
The method of displaying the geographical variability of the disease on maps using different colors, shading, etc. The logic is not new, but the arrival of computers and computer g
The generalization of the normal distribution used for the characterization of functions. It is known as a Gaussian process because it has Gaussian distributed finite dimensional m
An auditor for a government agency needs to evaluate payments for doctors' office visits paid by Medicare in a small regional town during the month of June. A total of 25,056 visit
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