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Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting joint null hypothesis.
The fraction of the observed significances at the given α-level is compared to the expected fraction under the joint null and the difference between the two quantities is standardized and this standardized value then maximized over the range of significance levels to provide the higher criticism statistic. This statistic is efficient in assessing whether n normal means are all zero against the alternative that the small fraction is nonzero.
The computer programs designed to mimic the role of the expert human consultant. This type of systems are capable to cope with the complex problems of the medical decision makin
Informed consent: The consent needed from each potential participant former to random assignment in the clinical trial as speci?ed in the year 1996 version of Helsinki declaration
Martingale: In the gambling context the term at first referred to a system for recouping losses by doubling the stake after each loss has occured. The modern mathematical concept
Genetic algorithms: The optimization events motivated by the biological analogies. The prime idea is to try to mimic the 'survival of the fittest' rule of the genetic mutation in
This term is sometimes used for the data collected in those longitudinal studies in which more than the single response variable is recorded for each subject on each occasion. For
Regression dilution is the term which is applied when a covariate in the model cannot be measured directly and instead of that a related observed value must be used in analysis. I
how does it work exactly
Case-cohort study : The research design in epidemiology which involves the sampling of controls at the outset of the study that is to be compared with the cases from the cohort. Th
Longini Koopman model : In epidemiology the model for primary and secondary infection, based on the classification of the extra-binomial variation in an infection rate which might
Build-Rite construction has received favorable publicity from guest appearances on a public TV home improvement program. Public TV programming decisions seem to be unpredictable, s
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