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To synthesize glycogen two enzymes are needed:
1. UDP-glucose pyrophosphorylase catalyzes the synthesis of UDP-glucose from UTP and glucose 1-phosphate:
The pyrophosphate (PPi) is right away hydrolyzed by inorganic pyrophosphatase, releasing energy. Thus the whole reaction is very exergonic and essentially irreversible.
2. Glycogen synthase now transfers the glucosyl residue from UDP-glucose to the C4 OH group at the nonreducing end of a glycogen molecule, forming a α1-4 glycosidic bond. Amusingly, glycogen synthase can only extend an existing chain. Thus it needs a primer; this is a protein called as glycogenin. Glycogenin holds eight glucosyl units linked via α1-4 link- ages, which are added to the protein by itself for instance Autocatalysis. It is this molecule which glycogen synthase then extends. Each glycogen granule have only a single glycogenin molecule at its core. The reality that glycogen synthase is fully active only when in contact with glycogenin limits the size of the glycogen granule.
Explain the energy flow of ecology? Energy flow: As you can see, energy flow is one way in an ecosystem. Energy is not recycled. The ultimate source of energy that powers eco
Mitral Valve Replacement : When mitral valve replacement for a calcified, stenotic valve is done, usually it is a classical procedure removing leaflets, their chordae an
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Amylase The presence of pancreatic amylase brings about the breakdown of starch and glycogen and its action is similar to salivary amylase. The hydrolysis of starch and gl
difference btn massflow and pressure law
Q. Saturated Fatty Acids required for dyslipidemia? Saturated Fatty Acids (SFA): These are found mostly in animal fats as white marble-like solid at room temperature. Red meats
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